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Nasdaq · CIK 0002042347

SPTX Seaport Therapeutics, Inc.

Insider trading from SEC Form 4. Last filing Jun 24, 2026. Close $18.15 on Oct 9, 2026, +19% from the 52-week low and -35% from the high.

In brief

Seaport Therapeutics, Inc. (SPTX) has 15 SEC Form 4 filings on file from 14 insiders, the latest filed on Jun 24, 2026. No insider bought or sold on the open market in the last 90 days; rows filed in that time are grants, exercises, tax withholding and other transactions that carry no view on the price.

2 open-market trades have been scored at SPTX. The newest: Robert J. Hombach (director) bought $236k of stock on Jun 22, 2026, filed Jun 24, 2026, scored 36 (weak). The largest of the 2 shown: ARCH Venture Partners XII, LLC (10% owner) bought $20M on May 4, 2026, scored 38 (weak).

Last 90 days

Net insider value
$0
no open-market trades
Buys
0
$0 by 0 insiders
Sells
0
$0 by 0 insiders
Insiders on file
14
with a Form 4 at this company

Price and insider trades, last year

SPTXOct 9, 2026 · close 18.15

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

Signals

Open-market buys and sells at Seaport Therapeutics, Inc., scored.

ScoreInsiderValueHoldingsPrice contextFiled
36WeakRobert J. Hombach
director
buy
$236k
13,000 shares
-+18% from low-9% from high
38WeakARCH Venture Partners XII, LLC
owner
buy
$20M
1,100,000 shares
+21%-

Transactions

Every row filed, 41 in all.

DateInsiderTransactionSharesPriceValueHoldings afterFiled
Jun 22, 2026Robert J. Hombach
director
POpen-market purchase
Common Stockindirect: By Robert Joseph Hombach Revocable Trust
+13,000$18.14$236k13,000Jun 24, 2026
May 4, 2026PureTech Health plc
owner
CConversion
Common Stockindirect: See footnote
+12,736,014--13,038,493May 6, 2026
May 4, 2026PureTech Health plc
owner
CConversion
Common Stockindirect: See footnote
+2,681,265--15,719,758May 6, 2026
May 4, 2026PureTech Health plc
owner
CConversion
Common Stockindirect: See footnote
+965,255--16,685,013May 6, 2026
May 4, 2026PureTech Health plc
owner
CConversion
Series A-1 Preferred Stockderivativeindirect: See footnote
-40,000,000$0.00$00May 6, 2026
May 4, 2026PureTech Health plc
owner
CConversion
Series A-2 Preferred Stockderivativeindirect: See footnote
-8,421,052$0.00$00May 6, 2026
May 4, 2026PureTech Health plc
owner
CConversion
Series B Preferred Stockderivativeindirect: See footnote
-3,031,578$0.00$00May 6, 2026
May 4, 2026ARCH Venture Partners XII, LLC
owner
CConversion
Common Stockindirect: By ARCH Venture Fund XII, L.P.
+2,513,686--2,513,686May 4, 2026
Apr 30, 2026Daphne Zohar
Chief Executive Officer
AGrant or award
Stock Option (Right to Buy)derivative
+271,813$0.00$0271,813May 4, 2026
Apr 30, 2026David E. Wheadon
director
AGrant or award
Stock Option (Right to Buy)derivative
+12,258$0.00$012,258May 4, 2026
Apr 30, 2026Sandra E Peterson
director
AGrant or award
Stock Option (Right to Buy)derivative
+12,258$0.00$012,258May 4, 2026
Apr 30, 2026Sharon Mates
director
AGrant or award
Stock Option (Right to Buy)derivative
+49,033$0.00$049,033May 4, 2026
Apr 30, 2026Robert J. Hombach
director
AGrant or award
Stock Option (Right to Buy)derivative
+12,258$0.00$012,258May 4, 2026
May 4, 2026Lauren White
Chief Financial Officer
CConversion
Common Stockindirect: By Lauren Anne White Living Trust, dated January 30, 2020
+6,702--6,702May 4, 2026
May 4, 2026Denice Torres
director
CConversion
Common Stockindirect: By Denice M. Torres Revocable Trust
+13,406--13,406May 4, 2026
May 4, 2026Steven M Paul
director
CConversion
Common Stock
+67,031--863,031May 4, 2026
May 4, 2026Antony Loebel
Chief Medical Officer
CConversion
Common Stock
+20,109--20,109May 4, 2026
May 4, 2026James Healy
director
CConversion
Common Stockindirect: By Sofinnova Venture Partners XI, L.P.
+1,927,159--1,927,159May 4, 2026
May 4, 2026Lana Gladstein
General Counsel
CConversion
Common Stock
+33,515--33,515May 4, 2026
May 4, 2026Michael Cunyuan Chen
Chief Scientific Officer
CConversion
Common Stock
+3,351--3,351May 4, 2026
Apr 30, 2026Michael Cunyuan Chen
Chief Scientific Officer
AGrant or award
Stock Option (Right to Buy)derivative
+63,680$0.00$063,680May 4, 2026
Apr 30, 2026Daphne Zohar
Chief Executive Officer
AGrant or award
Stock Option (Right to Buy)derivative
+1,486,786$0.00$01,486,786May 4, 2026
May 4, 2026ARCH Venture Partners XII, LLC
owner
CConversion
Common Stockindirect: By ARCH Venture Fund XII, L.P.
+2,681,265--5,194,951May 4, 2026
Apr 30, 2026Lauren White
Chief Financial Officer
AGrant or award
Stock Option (Right to Buy)derivative
+63,680$0.00$063,680May 4, 2026
Apr 30, 2026Denice Torres
director
AGrant or award
Stock Option (Right to Buy)derivative
+12,258$0.00$012,258May 4, 2026
Apr 30, 2026Steven M Paul
director
AGrant or award
Stock Option (Right to Buy)derivative
+12,258$0.00$012,258May 4, 2026
Apr 30, 2026Antony Loebel
Chief Medical Officer
AGrant or award
Stock Option (Right to Buy)derivative
+63,680$0.00$063,680May 4, 2026
Apr 30, 2026Lana Gladstein
General Counsel
AGrant or award
Stock Option (Right to Buy)derivative
+63,680$0.00$063,680May 4, 2026
May 4, 2026James Healy
director
CConversion
Common Stockindirect: By Sofinnova Venture Partners XI, L.P.
+804,379--2,731,538May 4, 2026
May 4, 2026Antony Loebel
Chief Medical Officer
CConversion
Series B Preferred Stockderivative
-63,157$0.00$00May 4, 2026
May 4, 2026Lauren White
Chief Financial Officer
CConversion
Series B Preferred Stockderivativeindirect: By Lauren Anne White Living Trust, dated January 30, 2020
-21,052$0.00$00May 4, 2026
May 4, 2026Michael Cunyuan Chen
Chief Scientific Officer
CConversion
Series B Preferred Stockderivative
-10,526$0.00$00May 4, 2026
May 4, 2026Denice Torres
director
CConversion
Series B Preferred Stockderivativeindirect: By Denice M. Torres Revocable Trust
-42,105$0.00$00May 4, 2026
May 4, 2026Lana Gladstein
General Counsel
CConversion
Series B Preferred Stockderivative
-105,263$0.00$00May 4, 2026
Apr 30, 2026Steven M Paul
director
AGrant or award
Stock Option (Right to Buy)derivative
+991,192$0.00$0991,192May 4, 2026
May 4, 2026ARCH Venture Partners XII, LLC
owner
POpen-market purchase
Common Stockindirect: By ARCH Venture Fund XII, L.P.
+1,100,000$18.00$20M6,294,951May 4, 2026
May 4, 2026James Healy
director
CConversion
Series A-2 Preferred Stockderivativeindirect: By Sofinnova Venture Partners XI, L.P.
-6,052,631$0.00$00May 4, 2026
May 4, 2026ARCH Venture Partners XII, LLC
owner
CConversion
Series A-2 Preferred Stockderivativeindirect: By ARCH Venture Fund XII, L.P.
-2,513,686$0.00$00May 4, 2026
May 4, 2026James Healy
director
CConversion
Series B Preferred Stockderivativeindirect: By Sofinnova Venture Partners XI, L.P.
-2,526,315$0.00$00May 4, 2026
May 4, 2026Steven M Paul
director
CConversion
Series B Preferred Stockderivative
-210,526$0.00$00May 4, 2026
May 4, 2026ARCH Venture Partners XII, LLC
owner
CConversion
Series B Preferred Stockderivativeindirect: By ARCH Venture Fund XII, L.P.
-2,681,265$0.00$00May 4, 2026

Insiders

Everyone who has filed a Form 4 here.

Questions about SPTX

Answered from the filings on this page, as of the latest one.

Are insiders buying SPTX?

No. In the last 90 days no insider at Seaport Therapeutics, Inc. bought or sold shares on the open market according to SEC Form 4 filings. The rows on file from that period are grants, exercises, tax withholding or other transactions, which carry no view on the price.

Who was the last insider to trade SPTX on the open market?

Robert J. Hombach (director) bought $236k of SPTX on Jun 22, 2026 and filed the Form 4 on Jun 24, 2026. InsiderTell scored 36 (weak).

How many insiders file Form 4 at Seaport Therapeutics, Inc.?

14 people have filed a Form 4 at Seaport Therapeutics, Inc., among them ARCH Venture Partners XII, LLC (10% owner and director), Michael Cunyuan Chen (Chief Scientific Officer), Lana Gladstein (General Counsel). Officers, directors and holders of more than 10% of a share class must report their trades within two business days.

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

SPTX insider trading: Seaport Therapeutics, Inc. | InsiderTell