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Insider · CIK 0001522780

Edward M. Kaye MD

ceoofficerdirector

Files at CYTK (CYTOKINETICS INC), RNA (Avidity Biosciences, Inc.), STOK (Stoke Therapeutics, Inc.). First filing Dec 10, 2024, latest Dec 2, 2025.

Track record
Not enough history
Fewer than three past buys with six months of prices.
Median 6-month excess
-
after past buys, n = 0
Hit rate
-
past buys that beat the index over 6 months
Open-market trades
0 / 11
$0 bought, $5.2M sold

Where the trades landed

Last year at the 2 companies this insider has traded most, with each buy and sell on the bar it happened.

CYTK: CYTOKINETICS INC

CYTKOct 9, 2026 · close 62.91

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

STOK: Stoke Therapeutics, Inc.

STOKOct 9, 2026 · close 24.74

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

Signals

This insider’s open-market buys and sells, scored.

ScoreCompanyValueHoldingsPrice contextFiled
40Moderate
CYTKsell 610b5-1
CYTOKINETICS INC
$1.9M
28,064 shares
-74%+121% from low-3% from high
20Weak
CYTKsell 410b5-1
CYTOKINETICS INC
$337k
5,175 shares
-34%+123% from low0% from high
36Weak
CYTKsell 310b5-1
CYTOKINETICS INC
$405k
6,757 shares
-41%+103% from low0% from high
35Weak
CYTKsell 310b5-1
CYTOKINETICS INC
$369k
6,695 shares
-29%+84% from low-6% from high
45Moderate
STOKsell 310b5-1
Stoke Therapeutics, Inc.
$1.2M
61,885 shares
-40%+235% from low-0% from high
30Weak
CYTKsell 410b5-1
CYTOKINETICS INC
$338k
6,756 shares
-23%+66% from low-15% from high
42Moderate
STOKsell 3
Stoke Therapeutics, Inc.
$221k
12,126 shares
-7%+214% from low0% from high
25Weak
CYTKsell 410b5-1
CYTOKINETICS INC
$117k
3,636 shares
-11%+8% from low-45% from high
39Weak
STOKsell 2
Stoke Therapeutics, Inc.
$164k
19,289 shares
-12%+20% from low-42% from high
49Moderate
STOKsell 4
Stoke Therapeutics, Inc.
$88k
6,786 shares
-10%+22% from low-10% from high
49Moderate
STOKsell 3
Stoke Therapeutics, Inc.
$79k
6,170 shares
-8%+18% from low-13% from high

Transactions

Every row this insider has filed, newest first.

DateCompanyTransactionSharesPriceValueHoldings afterFiled
Dec 1, 2025CYTK
CYTOKINETICS INC
MOption exercise
Common Stock10b5-1
+8,064$12.40$100k18,041Dec 2, 2025
Dec 1, 2025CYTK
CYTOKINETICS INC
MOption exercise
Common Stock10b5-1
+20,000$14.25$285k38,041Dec 2, 2025
Dec 1, 2025CYTK
CYTOKINETICS INC
SOpen-market sale
Common Stock10b5-1
-28,064$66.72$1.9M9,977Dec 2, 2025
Dec 1, 2025CYTK
CYTOKINETICS INC
MOption exercise
Non-Qualified Stock Option (Right to Buy)derivative10b5-1
-8,064$0.00$00Dec 2, 2025
Dec 1, 2025CYTK
CYTOKINETICS INC
MOption exercise
Non-Qualified Stock Option (Right to Buy)derivative10b5-1
-20,000$0.00$00Dec 2, 2025
Nov 11, 2025CYTK
CYTOKINETICS INC
MOption exercise
Common Stock10b5-1
+5,175$9.66$50k15,152Nov 12, 2025
Nov 11, 2025CYTK
CYTOKINETICS INC
SOpen-market sale
Common Stock10b5-1
-5,175$65.08$337k9,977Nov 12, 2025
Nov 11, 2025CYTK
CYTOKINETICS INC
MOption exercise
Non-Qualified Stock Option (Right to Buy)derivative10b5-1
-5,175$0.00$00Nov 12, 2025
Oct 15, 2025CYTK
CYTOKINETICS INC
AGrant or award
Common Stock
+199$62.80$12k9,977Oct 16, 2025
Oct 6, 2025CYTK
CYTOKINETICS INC
SOpen-market sale
Common Stock10b5-1
-6,757$60.00$405k9,778Oct 6, 2025
Sep 30, 2025CYTK
CYTOKINETICS INC
SOpen-market sale
Common Stock10b5-1
-6,695$55.08$369k16,535Sep 30, 2025
Sep 4, 2025STOK
Stoke Therapeutics, Inc.
DDisposition to issuer
Employee Stock Option (Right to Buy)derivative
-178,500$0.00$037,500Sep 5, 2025
Sep 4, 2025STOK
Stoke Therapeutics, Inc.
DDisposition to issuer
Restricted Stock Unitsderivative
-144,000$0.00$00Sep 5, 2025
Aug 29, 2025STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-1,029$20.00$21k152,441Sep 3, 2025
Sep 2, 2025STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-14,860$20.14$299k137,581Sep 3, 2025
Sep 3, 2025STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-45,996$20.13$926k91,585Sep 3, 2025
Sep 2, 2025CYTK
CYTOKINETICS INC
SOpen-market sale
Common Stock10b5-1
-6,756$50.00$338k23,230Sep 2, 2025
Aug 18, 2025STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock
-12,126$18.24$221k153,470Aug 20, 2025
Aug 14, 2025STOK
Stoke Therapeutics, Inc.
MOption exercise
Common Stock
+26,250$0.00$0165,596Aug 18, 2025
Aug 14, 2025STOK
Stoke Therapeutics, Inc.
AGrant or award
Performance Stock Unitsderivative
+52,500$0.00$052,500Aug 18, 2025
Aug 14, 2025STOK
Stoke Therapeutics, Inc.
MOption exercise
Performance Stock Unitsderivative
-26,250$0.00$026,250Aug 18, 2025
Jul 15, 2025CYTK
CYTOKINETICS INC
AGrant or award
Common Stock
+328$38.01$12k29,986Jul 16, 2025
Jun 10, 2025RNA
Avidity Biosciences, Inc.
AGrant or award
Common Stock
+6,692$0.00$06,692Jun 12, 2025
Jun 10, 2025RNA
Avidity Biosciences, Inc.
AGrant or award
Stock Option (Right to Buy)derivative
+10,034$0.00$010,034Jun 12, 2025
Jun 5, 2025CYTK
CYTOKINETICS INC
SOpen-market sale
Common Stock10b5-1
-3,636$32.10$117k29,658Jun 5, 2025
May 14, 2025CYTK
CYTOKINETICS INC
AGrant or award
Common Stock
+7,333$0.00$033,294May 14, 2025
May 14, 2025CYTK
CYTOKINETICS INC
AGrant or award
Non-Qualified Stock Option (Right to Buy)derivative
+10,880$0.00$010,880May 14, 2025
Apr 15, 2025CYTK
CYTOKINETICS INC
AGrant or award
Common Stock
+324$38.56$12k25,961Apr 16, 2025
Mar 18, 2025STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock
-10,382$8.67$90k148,253Mar 20, 2025
Mar 19, 2025STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock
-8,907$8.27$74k139,346Mar 20, 2025
Mar 20, 2025STOK
Stoke Therapeutics, Inc.
AGrant or award
Employee Stock Option (Right to Buy)derivative
+216,000$0.00$0216,000Mar 20, 2025
Mar 20, 2025STOK
Stoke Therapeutics, Inc.
AGrant or award
Restricted Stock Unitsderivative
+144,000$0.00$0144,000Mar 20, 2025
Mar 15, 2025STOK
Stoke Therapeutics, Inc.
MOption exercise
Common Stock
+35,500$0.00$0132,385Mar 18, 2025
Mar 15, 2025STOK
Stoke Therapeutics, Inc.
MOption exercise
Common Stock
+26,250$0.00$0158,635Mar 18, 2025
Mar 15, 2025STOK
Stoke Therapeutics, Inc.
MOption exercise
Restricted Stock Unitsderivative
-35,500$0.00$071,000Mar 18, 2025
Mar 15, 2025STOK
Stoke Therapeutics, Inc.
MOption exercise
Restricted Stock Unitsderivative
-26,250$0.00$078,750Mar 18, 2025
Jan 2, 2025CYTK
CYTOKINETICS INC
AGrant or award
Common Stock
+255$48.93$12k25,637Jan 6, 2025
Dec 30, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Common Stock
+35,000$0.60$21k96,885Jan 2, 2025
Dec 30, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Employee Stock Option (Right to Buy)derivative
-35,000$0.00$0567,801Jan 2, 2025
Dec 9, 2024STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock
-6,786$12.99$88k61,885Dec 11, 2024
Dec 6, 2024STOK
Stoke Therapeutics, Inc.
SOpen-market sale
Common Stock
-6,170$12.78$79k68,671Dec 10, 2024
Dec 3, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Common Stock
+26,250$0.00$074,841Dec 10, 2024
Dec 3, 2024STOK
Stoke Therapeutics, Inc.
AGrant or award
Performance Stock Unitsderivative
+52,500$0.00$052,500Dec 10, 2024
Dec 3, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Performance Stock Unitsderivative
-26,250$0.00$026,250Dec 10, 2024
Dec 3, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Common Stock
+26,500$0.00$075,091Dec 5, 2024
Dec 3, 2024STOK
Stoke Therapeutics, Inc.
AGrant or award
Performance Stock Unitsderivative
+53,000$0.00$053,000Dec 5, 2024
Dec 3, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Performance Stock Unitsderivative
-26,500$0.00$026,500Dec 5, 2024
Dec 1, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Common Stock
+21,591$0.00$048,591Dec 3, 2024
Dec 1, 2024STOK
Stoke Therapeutics, Inc.
MOption exercise
Restricted Stock Unit (RSU)derivative
-21,591$0.00$04,317Dec 3, 2024

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.