Insider · CIK 0001595855
Opaleye Management Inc.
owner
Files at CDXS (CODEXIS, INC.), HROW (HARROW, INC.), SNWV (SANUWAVE Health, Inc.), GRCE (Grace Therapeutics, Inc.), ACOG (Alpha Cognition Inc.), SLGL (Sol-Gel Technologies Ltd.), ETON (Eton Pharmaceuticals, Inc.). First filing Oct 25, 2024, latest Oct 5, 2026.
Track record
Strong
Past buys beat the index by more than 10% over six months, median.
Median 6-month excess
+95.1%
after past buys, n = 3
Hit rate
67%
past buys that beat the index over 6 months
Open-market trades
54 / 14
$19M bought, $11M sold
Where the trades landed
Last year at the 3 companies this insider has traded most, with each buy and sell on the bar it happened.
CDXS: CODEXIS, INC.
CDXSOct 9, 2026 · close 1.41
Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™
ACOG: Alpha Cognition Inc.
ACOGOct 9, 2026 · close 9.04
Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™
SLGL: Sol-Gel Technologies Ltd.
SLGLOct 9, 2026 · close 71.77
Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™
Signals
This insider’s open-market buys and sells, scored.
| Score | Company | Value | Holdings | Price context | Filed |
|---|---|---|---|---|---|
| 40Moderate | GRCEbuy Grace Therapeutics, Inc. | $124k 60,490 shares | +2% | 0% from low-60% from high | |
| 18Weak | ACOGbuy Alpha Cognition Inc. | $166k 19,050 shares | +1% | +93% from low-11% from high | |
| 25Weak | GRCEbuy Grace Therapeutics, Inc. | $16k 7,849 shares | +0% | +2% from low-59% from high | |
| 38Weak | Grace Therapeutics, Inc. | $32k 15,089 shares | +1% | +1% from low-59% from high | |
| 25Weak | ACOGbuy Alpha Cognition Inc. | $271k 31,763 shares | +1% | +90% from low-12% from high | |
| 38Weak | Grace Therapeutics, Inc. | $32k 15,089 shares | +1% | +1% from low-59% from high | |
| 32Weak | ACOGbuy Alpha Cognition Inc. | $1.1M 123,918 shares | +4% | +94% from low-11% from high | |
| 19Weak | SLGLbuy Sol-Gel Technologies Ltd. | $207k 3,124 shares | +1% | - | |
| 33Weak | Grace Therapeutics, Inc. | $32k 15,229 shares | +1% | +2% from low-59% from high | |
| 33Weak | SLGLbuy Sol-Gel Technologies Ltd. | $687k 9,976 shares | +2% | - | |
| 12Weak | SLGLbuy Sol-Gel Technologies Ltd. | $116k 1,683 shares | +0% | - | |
| 32Weak | ACOGbuy Alpha Cognition Inc. | $60k 11,850 shares | +0% | +35% from low-55% from high | |
| 35Weak | ACOGbuy Alpha Cognition Inc. | $109k 20,082 shares | +1% | +49% from low-50% from high | |
| 30Weak | ACOGbuy Alpha Cognition Inc. | $26k 4,575 shares | +0% | +53% from low-49% from high | |
| 25Weak | ACOGbuy Alpha Cognition Inc. | $7,696 1,331 shares | +0% | +54% from low-48% from high | |
| 33Weak | ACOGbuy Alpha Cognition Inc. | $76k 13,066 shares | +1% | +56% from low-48% from high | |
| 25Weak | ACOGbuy Alpha Cognition Inc. | $24k 4,079 shares | +0% | +54% from low-48% from high | |
| 46Moderate | ACOGbuy Alpha Cognition Inc. | $388k 66,818 shares | +3% | +56% from low-48% from high | |
| 46Moderate | ACOGbuy Alpha Cognition Inc. | $412k 71,411 shares | +3% | +55% from low-48% from high | |
| 30Weak | ACOGbuy Alpha Cognition Inc. | $25k 4,228 shares | +0% | +60% from low-47% from high | |
| 53Moderate | ACOGbuy Alpha Cognition Inc. | $1.0M 171,410 shares | +8% | +56% from low-48% from high | |
| 50Moderate | SLGLbuy Sol-Gel Technologies Ltd. | $2.8M 66,304 shares | +18% | +986% from low0% from high | |
| 27Weak | SLGLbuy Sol-Gel Technologies Ltd. | $121k 2,905 shares | +1% | +928% from low-2% from high | |
| 27Weak | SLGLbuy Sol-Gel Technologies Ltd. | $110k 2,735 shares | +1% | +904% from low-4% from high | |
| 17Weak | SLGLbuy Sol-Gel Technologies Ltd. | $3,480 87 shares | +0% | +851% from low-9% from high | |
| 52Moderate | CODEXIS, INC. | $1.9M 1,063,211 shares | -8% | 0% from low-71% from high | |
| 43Moderate | CODEXIS, INC. | $878k 514,341 shares | -5% | +13% from low-70% from high | |
| 22Weak | SLGLbuy Sol-Gel Technologies Ltd. | $29k 744 shares | +0% | +888% from low-6% from high | |
| 35Weak | SLGLbuy Sol-Gel Technologies Ltd. | $258k 6,864 shares | +2% | +843% from low-10% from high | |
| 43Moderate | CODEXIS, INC. | $878k 514,341 shares | -5% | +13% from low-70% from high | |
| 23Weak | SLGLbuy Sol-Gel Technologies Ltd. | $38k 949 shares | +0% | +919% from low-3% from high | |
| 33Weak | SLGLbuy Sol-Gel Technologies Ltd. | $207k 5,784 shares | +2% | +772% from low-17% from high | |
| 52Moderate | CODEXIS, INC. | $2.1M 1,082,459 shares | -9% | +14% from low-67% from high | |
| 52Moderate | CODEXIS, INC. | $1.9M 1,063,211 shares | -8% | 0% from low-71% from high | |
| 18Weak | SNWVbuy SANUWAVE Health, Inc. | $38k 1,267 shares | +0% | +213% from low-9% from high | |
| 38Weak | CDXSbuy CODEXIS, INC. | $228k 85,000 shares | +1% | +36% from low-54% from high | |
| 30Weak | CDXSbuy CODEXIS, INC. | $28k 10,000 shares | +0% | +43% from low-51% from high | |
| 39Weak | CDXSbuy CODEXIS, INC. | $282k 100,000 shares | +1% | +43% from low-51% from high | |
| 38Weak | CDXSbuy CODEXIS, INC. | $239k 100,000 shares | +1% | +21% from low-59% from high | |
| 49Moderate | CDXSbuy CODEXIS, INC. | $560k 250,000 shares | +2% | +14% from low-61% from high | |
| 27Weak | ETONbuy Eton Pharmaceuticals, Inc. | $125k 7,930 shares | +0% | +228% from low-22% from high | |
| 46Moderate | HROWsell HARROW, INC. | $924k 30,204 shares | -25% | +36% from low-48% from high | |
| 23Weak | HROWsell HARROW, INC. | $144k 4,796 shares | -4% | +32% from low-49% from high | |
| 61Notable | CDXSbuy CODEXIS, INC. | $5.5M 2,325,000 shares | +24% | +22% from low-59% from high | |
| 33Weak | HROWsell HARROW, INC. | $392k 15,000 shares | -11% | +20% from low-54% from high | |
| 23Weak | HROWsell HARROW, INC. | $150k 5,000 shares | -3% | +35% from low-48% from high | |
| 23Weak | HROWsell HARROW, INC. | $148k 5,000 shares | -3% | +21% from low-53% from high | |
| 35Weak | CDXSbuy CODEXIS, INC. | $104k 45,000 shares | +0% | +17% from low-60% from high | |
| 32Weak | SNWVbuy SANUWAVE Health, Inc. | $204k 7,998 shares | +1% | +98% from low-33% from high | |
| 32Weak | CDXSbuy CODEXIS, INC. | $56k 25,000 shares | +0% | +15% from low-61% from high | |
| 44Moderate | CDXSbuy CODEXIS, INC. | $299k 140,000 shares | +1% | +14% from low-61% from high | |
| 52Moderate | CDXSbuy CODEXIS, INC. | $198k 100,000 shares | +1% | 0% from low-66% from high | |
| 53Moderate | CDXSbuy CODEXIS, INC. | $272k 115,000 shares | +1% | 0% from low-57% from high | |
| 23Weak | HROWsell HARROW, INC. | $150k 5,000 shares | -3% | +21% from low-53% from high | |
| 43Moderate | CDXSbuy CODEXIS, INC. | $236k 92,930 shares | +1% | +1% from low-56% from high | |
| 23Weak | HROWsell HARROW, INC. | $148k 5,000 shares | -3% | +21% from low-53% from high | |
| 19Weak | CDXSbuy CODEXIS, INC. | $216k 85,000 shares | +1% | - | |
| 25Weak | CDXSbuy CODEXIS, INC. | $261k 100,000 shares | +1% | - | |
| 18Weak | CDXSbuy CODEXIS, INC. | $172k 65,000 shares | +1% | - | |
| 31Weak | CDXSbuy CODEXIS, INC. | $574k 195,000 shares | +2% | - | |
| 23Weak | HROWsell HARROW, INC. | $140k 5,000 shares | -3% | - | |
| 19Weak | CDXSbuy CODEXIS, INC. | $205k 50,000 shares | +1% | - | |
| 21Weak | CDXSbuy CODEXIS, INC. | $283k 65,000 shares | +1% | - | |
| 38Weak | HROWsell HARROW, INC. | $712k 20,000 shares | -11% | - | |
| 19Weak | CDXSbuy CODEXIS, INC. | $211k 45,000 shares | +1% | - | |
| 32Weak | SANUWAVE Health, Inc. | $439k 27,868 shares | +3% | - | |
| 10Weak | CDXSbuy CODEXIS, INC. | $73k 25,000 shares | +0% | - | |
| 11Weak | ETONbuy Eton Pharmaceuticals, Inc. | $80k 10,000 shares | +0% | - |
Transactions
Every row this insider has filed, newest first.
| Date | Company | Transaction | Shares | Price | Value | Holdings after | Filed |
|---|---|---|---|---|---|---|---|
| Oct 1, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +38,796 | $2.04 | $79k | 2,836,963 | 7 d ago |
| Oct 2, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +20,000 | $2.07 | $41k | 2,856,963 | 7 d ago |
| Oct 5, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +1,694 | $2.06 | $3,490 | 2,858,657 | 7 d ago |
| Oct 1, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +19,050 | $8.69 | $166k | 3,222,954 | 10 d ago |
| Sep 29, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +7,849 | $2.09 | $16k | 2,798,167 | 11 d ago |
| Sep 21, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +9,771 | $2.10 | $21k | 2,785,000 | 11 d ago |
| Sep 23, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +5,318 | $2.10 | $11k | 2,790,318 | 11 d ago |
| Sep 24, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +18,337 | $8.57 | $157k | 3,190,478 | 14 d ago |
| Sep 25, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +13,426 | $8.47 | $114k | 3,203,904 | 14 d ago |
| Sep 21, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +9,771 | $2.10 | $21k | 2,850,000 | 19 d ago |
| Sep 23, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +5,318 | $2.10 | $11k | 2,855,318 | 19 d ago |
| Sep 14, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +40,373 | $8.70 | $351k | 3,088,596 | 26 d ago |
| Sep 15, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +3,375 | $8.54 | $29k | 3,091,971 | 26 d ago |
| Sep 16, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +53,029 | $8.57 | $455k | 3,145,000 | 26 d ago |
| Sep 16, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +27,141 | $8.40 | $228k | 3,172,141 | 26 d ago |
| Sep 10, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +1,631 | $66.80 | $109k | 538,507 | 28 d ago |
| Sep 11, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +1,493 | $65.95 | $98k | 540,000 | 28 d ago |
| Sep 8, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +9,393 | $2.10 | $20k | 2,769,393 | 32 d ago |
| Sep 9, 2026 | GRCE Grace Therapeutics, Inc. | POpen-market purchase Common Stock, par value $0.0001 per shareindirect: By Opaleye, L.P. | +5,836 | $2.09 | $12k | 2,775,229 | 32 d ago |
| Sep 4, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +918 | $69.52 | $64k | 527,818 | 33 d ago |
| Sep 4, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +2,100 | $68.98 | $145k | 529,918 | 33 d ago |
| Sep 8, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +3,390 | $68.74 | $233k | 533,308 | 33 d ago |
| Sep 8, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +471 | $69.37 | $33k | 533,779 | 33 d ago |
| Sep 9, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +3,097 | $68.71 | $213k | 536,876 | 33 d ago |
| Sep 1, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +783 | $69.52 | $54k | 526,000 | 39 d ago |
| Sep 2, 2026 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per shareindirect: By Opaleye, L.P. | +900 | $68.95 | $62k | 526,900 | 39 d ago |
| Mar 27, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +10,000 | $5.08 | $51k | 2,470,000 | Mar 31, 2026 |
| Mar 30, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +1,850 | $4.99 | $9,227 | 2,471,850 | Mar 31, 2026 |
| Mar 24, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +4,182 | $5.59 | $23k | 2,444,100 | Mar 26, 2026 |
| Mar 25, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +8,581 | $5.43 | $47k | 2,452,681 | Mar 26, 2026 |
| Mar 26, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +7,319 | $5.28 | $39k | 2,460,000 | Mar 26, 2026 |
| Mar 18, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +2,481 | $5.75 | $14k | 2,437,824 | Mar 20, 2026 |
| Mar 19, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +2,094 | $5.71 | $12k | 2,439,918 | Mar 20, 2026 |
| Mar 16, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +1,331 | $5.78 | $7,696 | 2,435,343 | Mar 18, 2026 |
| Mar 12, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +5,708 | $5.85 | $33k | 2,426,654 | Mar 13, 2026 |
| Mar 13, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +7,358 | $5.75 | $42k | 2,434,012 | Mar 13, 2026 |
| Mar 6, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +1,900 | $5.80 | $11k | 2,418,767 | Mar 10, 2026 |
| Mar 9, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +2,179 | $5.85 | $13k | 2,420,946 | Mar 10, 2026 |
| Mar 4, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +19,795 | $5.81 | $115k | 2,374,844 | Mar 6, 2026 |
| Mar 5, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +42,023 | $5.80 | $244k | 2,416,867 | Mar 6, 2026 |
| Mar 5, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Managed Account | +5,000 | $5.80 | $29k | 90,000 | Mar 6, 2026 |
| Mar 2, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +20,000 | $5.80 | $116k | 2,308,638 | Mar 4, 2026 |
| Mar 3, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +46,411 | $5.75 | $267k | 2,355,049 | Mar 4, 2026 |
| Mar 3, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Managed Account | +5,000 | $5.75 | $29k | 85,000 | Mar 4, 2026 |
| Feb 26, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +590 | $5.99 | $3,531 | 2,285,000 | Mar 2, 2026 |
| Feb 27, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +3,638 | $5.99 | $22k | 2,288,638 | Mar 2, 2026 |
| Feb 20, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +10,000 | $5.84 | $58k | 2,135,000 | Feb 24, 2026 |
| Feb 20, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Managed Account | +2,819 | $5.84 | $16k | 70,819 | Feb 24, 2026 |
| Feb 23, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +95,819 | $5.89 | $565k | 2,230,819 | Feb 24, 2026 |
| Feb 23, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Managed Account | +4,181 | $5.89 | $25k | 75,000 | Feb 24, 2026 |
| Feb 24, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Opaleye, L.P. | +53,591 | $5.80 | $311k | 2,284,410 | Feb 24, 2026 |
| Feb 24, 2026 | ACOG Alpha Cognition Inc. | POpen-market purchase Common Stock, no par valueindirect: By Managed Account | +5,000 | $5.80 | $29k | 80,000 | Feb 24, 2026 |
| Dec 29, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +8,638 | $41.85 | $362k | 386,073 | Dec 31, 2025 |
| Dec 30, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +35,169 | $41.99 | $1.5M | 421,242 | Dec 31, 2025 |
| Dec 31, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +22,497 | $41.99 | $945k | 443,739 | Dec 31, 2025 |
| Dec 22, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +1,019 | $41.15 | $42k | 375,549 | Dec 29, 2025 |
| Dec 23, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +260 | $41.66 | $11k | 375,809 | Dec 29, 2025 |
| Dec 26, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +1,626 | $41.68 | $68k | 377,435 | Dec 29, 2025 |
| Dec 17, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +2,735 | $40.37 | $110k | 374,530 | Dec 19, 2025 |
| Dec 12, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +87 | $40.00 | $3,480 | 371,795 | Dec 16, 2025 |
| Nov 7, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -296,682 | $1.70 | $503k | 12,248,318 | Dec 15, 2025 |
| Nov 26, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -148,318 | $1.74 | $258k | 10,305,000 | Dec 15, 2025 |
| Nov 26, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $1.74 | $8,707 | 191,012 | Dec 15, 2025 |
| Nov 7, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -10,000 | $1.70 | $17k | 240,000 | Dec 15, 2025 |
| Nov 10, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -205,000 | $1.73 | $356k | 12,043,318 | Dec 15, 2025 |
| Nov 28, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -105,000 | $1.75 | $184k | 10,200,000 | Dec 15, 2025 |
| Nov 10, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -3,318 | $1.73 | $5,756 | 236,682 | Dec 15, 2025 |
| Nov 28, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -2,490 | $1.75 | $4,358 | 188,522 | Dec 15, 2025 |
| Nov 11, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -535,000 | $1.80 | $963k | 11,508,318 | Dec 15, 2025 |
| Dec 1, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -245,000 | $1.67 | $409k | 9,955,000 | Dec 15, 2025 |
| Dec 1, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -8,533 | $1.67 | $14k | 179,989 | Dec 15, 2025 |
| Nov 11, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -13,211 | $1.80 | $24k | 223,461 | Dec 15, 2025 |
| Dec 5, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +444 | $39.50 | $18k | 371,408 | Dec 9, 2025 |
| Dec 8, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +300 | $39.78 | $12k | 371,708 | Dec 9, 2025 |
| Dec 1, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +4,340 | $37.37 | $162k | 368,440 | Dec 3, 2025 |
| Dec 3, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +2,524 | $37.81 | $95k | 370,964 | Dec 3, 2025 |
| Nov 26, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +148,318 | $1.74 | $258k | 10,305,000 | Dec 1, 2025 |
| Nov 26, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $1.74 | $8,707 | 191,012 | Dec 1, 2025 |
| Nov 28, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -105,000 | $1.75 | $184k | 10,200,000 | Dec 1, 2025 |
| Nov 28, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -2,490 | $1.75 | $4,358 | 188,522 | Dec 1, 2025 |
| Dec 1, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -245,000 | $1.67 | $409k | 9,955,000 | Dec 1, 2025 |
| Dec 1, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -8,533 | $1.67 | $14k | 179,989 | Dec 1, 2025 |
| Nov 24, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +6 | $35.50 | $213 | 363,157 | Nov 26, 2025 |
| Nov 26, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +943 | $40.00 | $38k | 364,100 | Nov 26, 2025 |
| Nov 20, 2025 | SLGL Sol-Gel Technologies Ltd. | POpen-market purchase Ordinary Shares, par value NIS 1.00 per share.indirect: By Opaleye, L.P. | +5,784 | $35.83 | $207k | 363,151 | Nov 21, 2025 |
| Nov 12, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +890,000 | $1.94 | $1.7M | 10,618,318 | Nov 14, 2025 |
| Nov 12, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -27,459 | $1.94 | $53k | 196,012 | Nov 14, 2025 |
| Nov 12, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -165,000 | $1.96 | $324k | 10,453,318 | Nov 14, 2025 |
| Nov 7, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +296,682 | $1.70 | $503k | 12,248,318 | Nov 12, 2025 |
| Nov 7, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -10,000 | $1.70 | $17k | 240,000 | Nov 12, 2025 |
| Nov 10, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -205,000 | $1.73 | $356k | 12,043,318 | Nov 12, 2025 |
| Nov 10, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -3,318 | $1.73 | $5,756 | 236,682 | Nov 12, 2025 |
| Nov 11, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | -535,000 | $1.80 | $963k | 11,508,318 | Nov 12, 2025 |
| Nov 11, 2025 | CDXS CODEXIS, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -13,211 | $1.80 | $24k | 223,461 | Nov 12, 2025 |
| Oct 6, 2025 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +1,267 | $30.28 | $38k | 966,267 | Oct 9, 2025 |
| Jul 31, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +84,220 | $2.68 | $226k | 12,544,220 | Aug 4, 2025 |
| Aug 4, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +780 | $2.84 | $2,211 | 12,545,000 | Aug 4, 2025 |
| Jul 29, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +8,422 | $2.82 | $24k | 12,458,422 | Jul 31, 2025 |
| Jul 30, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +1,578 | $2.80 | $4,411 | 12,460,000 | Jul 31, 2025 |
| Jul 18, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +100,000 | $2.82 | $282k | 12,450,000 | Jul 22, 2025 |
| Jun 27, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +100,000 | $2.39 | $239k | 12,350,000 | Jul 1, 2025 |
| Jun 12, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +100,000 | $2.25 | $225k | 12,100,000 | Jun 16, 2025 |
| Jun 13, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +99,102 | $2.23 | $221k | 12,199,102 | Jun 16, 2025 |
| Jun 16, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +50,898 | $2.24 | $114k | 12,250,000 | Jun 16, 2025 |
| Jun 10, 2025 | ETON Eton Pharmaceuticals, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +5,000 | $15.82 | $79k | 2,770,000 | Jun 12, 2025 |
| Jun 10, 2025 | ETON Eton Pharmaceuticals, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: Managed Account | +2,930 | $15.82 | $46k | 85,000 | Jun 12, 2025 |
| Jun 9, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -15,204 | $30.37 | $462k | 105,000 | Jun 11, 2025 |
| Jun 10, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -15,000 | $30.80 | $462k | 90,000 | Jun 11, 2025 |
| Jun 3, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -3,000 | $30.04 | $90k | 122,000 | Jun 5, 2025 |
| Jun 4, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -1,796 | $30.02 | $54k | 120,204 | Jun 5, 2025 |
| May 23, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +2,320,000 | $2.36 | $5.5M | 11,995,000 | May 28, 2025 |
| May 28, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +5,000 | $2.36 | $12k | 12,000,000 | May 28, 2025 |
| Mar 24, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $30.01 | $150k | 140,000 | May 14, 2025 |
| Mar 18, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $29.64 | $148k | 145,000 | May 14, 2025 |
| May 12, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -10,000 | $25.90 | $259k | 130,000 | May 14, 2025 |
| May 13, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $26.59 | $133k | 125,000 | May 14, 2025 |
| Apr 30, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +25,000 | $2.31 | $58k | 9,655,000 | May 2, 2025 |
| May 1, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +20,000 | $2.32 | $46k | 9,675,000 | May 2, 2025 |
| Apr 29, 2025 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +5,000 | $25.49 | $127k | 965,000 | Apr 30, 2025 |
| Apr 29, 2025 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Managed account | +2,998 | $25.49 | $76k | 15,000 | Apr 30, 2025 |
| Apr 25, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +25,000 | $2.24 | $56k | 9,630,000 | Apr 29, 2025 |
| Apr 15, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +25,000 | $2.23 | $56k | 9,490,000 | Apr 17, 2025 |
| Apr 16, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +70,000 | $2.13 | $149k | 9,560,000 | Apr 17, 2025 |
| Apr 17, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +45,000 | $2.09 | $94k | 9,605,000 | Apr 17, 2025 |
| Apr 8, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +100,000 | $1.98 | $198k | 9,465,000 | Apr 9, 2025 |
| Apr 1, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +35,000 | $2.48 | $87k | 9,285,000 | Apr 3, 2025 |
| Apr 2, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +5,000 | $2.46 | $12k | 9,290,000 | Apr 3, 2025 |
| Apr 3, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +75,000 | $2.30 | $173k | 9,365,000 | Apr 3, 2025 |
| Mar 18, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $30.01 | $150k | 140,000 | Mar 26, 2025 |
| Mar 20, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +7 | $2.54 | $18 | 9,157,077 | Mar 24, 2025 |
| Mar 21, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +92,923 | $2.54 | $236k | 9,250,000 | Mar 24, 2025 |
| Mar 18, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $29.64 | $148k | 145,000 | Mar 20, 2025 |
| Mar 13, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +85,000 | $2.54 | $216k | 9,150,000 | Mar 14, 2025 |
| Mar 6, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +100,000 | $2.61 | $261k | 9,065,000 | Mar 10, 2025 |
| Mar 4, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +55,000 | $2.64 | $145k | 8,955,000 | Mar 6, 2025 |
| Mar 5, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +10,000 | $2.69 | $27k | 8,965,000 | Mar 6, 2025 |
| Feb 28, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -5,000 | $28.05 | $140k | 150,000 | Mar 4, 2025 |
| Feb 28, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +147,649 | $2.99 | $441k | 8,852,649 | Mar 4, 2025 |
| Mar 3, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +47,351 | $2.81 | $133k | 8,900,000 | Mar 4, 2025 |
| Feb 10, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +22,500 | $4.18 | $94k | 8,677,500 | Feb 12, 2025 |
| Feb 11, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +12,500 | $4.11 | $51k | 8,690,000 | Feb 12, 2025 |
| Feb 12, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +15,000 | $4.00 | $60k | 8,705,000 | Feb 12, 2025 |
| Jan 30, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +20,000 | $4.49 | $90k | 8,610,000 | Jan 31, 2025 |
| Jan 31, 2025 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +45,000 | $4.29 | $193k | 8,655,000 | Jan 31, 2025 |
| Jan 22, 2025 | HROW HARROW, INC. | SOpen-market sale Common Stock, par value $0.001 per shareindirect: By Managed Account | -20,000 | $35.59 | $712k | 155,000 | Jan 24, 2025 |
| Dec 30, 2024 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +35,000 | $4.70 | $164k | 8,580,000 | Jan 2, 2025 |
| Dec 31, 2024 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +10,000 | $4.66 | $47k | 8,590,000 | Jan 2, 2025 |
| Oct 30, 2024 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +2,000 | $17.50 | $35k | 946,134 | Nov 1, 2024 |
| Oct 31, 2024 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +5,868 | $16.29 | $96k | 952,002 | Nov 1, 2024 |
| Oct 31, 2024 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Managed account | +4,000 | $16.29 | $65k | 4,000 | Nov 1, 2024 |
| Nov 1, 2024 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +7,998 | $15.20 | $122k | 960,000 | Nov 1, 2024 |
| Nov 1, 2024 | SNWV SANUWAVE Health, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Managed account | +8,002 | $15.20 | $122k | 12,002 | Nov 1, 2024 |
| Oct 25, 2024 | CDXS CODEXIS, INC. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +25,000 | $2.91 | $73k | 8,545,000 | Oct 28, 2024 |
| Oct 23, 2024 | ETON Eton Pharmaceuticals, Inc. | POpen-market purchase Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P. | +10,000 | $7.98 | $80k | 2,770,000 | Oct 25, 2024 |
Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.