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Nasdaq · CIK 0001701108

SPRO Spero Therapeutics, Inc.

Insider trading from SEC Form 4. Last filing Sep 3, 2025. Close $1.20 on Oct 9, 2026, +8% from the 52-week low and -60% from the high.

Last 90 days

Net insider value
$0
no open-market trades
Buys
0
$0 by 0 insiders
Sells
0
$0 by 0 insiders
Insiders on file
10
with a Form 4 at this company

Price and insider trades, last year

SPROOct 9, 2026 · close 1.20

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

Signals

Open-market buys and sells at Spero Therapeutics, Inc., scored.

ScoreInsiderValueHoldingsPrice contextFiled
28WeakTimothy Keutzer
Chief Operating Officer
sell
$3,339
1,695 shares
-0%+257% from low-34% from high
23WeakAnkit Mahadevia
director
sell
$13k
6,572 shares
-1%+257% from low-34% from high
26WeakTimothy Keutzer
Chief Operating Officer
sell
$44k
56,537 shares
-7%-
29WeakEsther Rajavelu
CFO & CBO
sell
$53k
40,596 shares
-10%-

Transactions

The last 17 rows filed, every code.

DateInsiderTransactionSharesPriceValueHoldings afterFiled
Aug 28, 2025Ankit Mahadevia
director
SOpen-market sale
Common Stock
-6,572$1.97$13k703,294Sep 3, 2025
Aug 28, 2025Timothy Keutzer
Chief Operating Officer
SOpen-market sale
Common Stock
-1,695$1.97$3,339739,744Sep 3, 2025
Jun 12, 2025Frank E Thomas
director
AGrant or award
Common Stock
+20,000$0.00$075,000Jun 16, 2025
Jun 12, 2025Patrick V.j.j. Vink
director
AGrant or award
Common Stock
+20,000$0.00$075,000Jun 16, 2025
Jun 12, 2025Kathleen Tregoning
director
AGrant or award
Common Stock
+20,000$0.00$075,000Jun 16, 2025
Jun 12, 2025Cynthia Smith
director
AGrant or award
Common Stock
+20,000$0.00$075,000Jun 16, 2025
Jun 12, 2025John C Pottage Jr
director
AGrant or award
Common Stock
+20,000$0.00$075,000Jun 16, 2025
Jun 12, 2025Ankit Mahadevia
director
AGrant or award
Common Stock
+20,000$0.00$0709,866Jun 16, 2025
Jun 12, 2025Scott Thomas Jackson
director
AGrant or award
Common Stock
+20,000$0.00$075,000Jun 16, 2025
Jun 12, 2025Milind Deshpande
director
AGrant or award
Common Stock
+20,000$0.00$091,454Jun 16, 2025
May 2, 2025Esther Rajavelu
See Remarks
AGrant or award
Common Stock
+185,000$0.00$0909,720May 6, 2025
Feb 3, 2025Timothy Keutzer
Chief Operating Officer
AGrant or award
Common Stock
+266,139$0.00$0797,976Feb 5, 2025
Feb 5, 2025Timothy Keutzer
Chief Operating Officer
SOpen-market sale
Common Stock
-3,974$0.78$3,100794,002Feb 5, 2025
Feb 5, 2025Timothy Keutzer
Chief Operating Officer
SOpen-market sale
Common Stock
-27,643$0.78$22k766,359Feb 5, 2025
Feb 5, 2025Timothy Keutzer
Chief Operating Officer
SOpen-market sale
Common Stock
-24,920$0.78$19k741,439Feb 5, 2025
Nov 7, 2024Esther Rajavelu
CFO & CBO
SOpen-market sale
Common Stock
-23,351$1.31$31k396,515Nov 12, 2024
Nov 8, 2024Esther Rajavelu
CFO & CBO
SOpen-market sale
Common Stock
-17,245$1.30$22k379,270Nov 12, 2024

Insiders

Everyone who has filed a Form 4 here.

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

SPRO insider trading: Spero Therapeutics, Inc. | InsiderTell