Skip to content
sellWeak cluster of 2

Timothy Keutzer sold $101k of SPRO

Chief Operating Officer at Spero Therapeutics, Inc.. 46,586 shares at an average of $2.17, traded Feb 2, 2026, filed Feb 5, 2026.

Warning score
38
Value
$101k
46,586 shares
Holdings after
761,158
-6% from before
From 52-week low
+298%
low $0.56, close $2.23
From 52-week high
-27%
high $3.04, as of Feb 2, 2026

Score components

  • Role
    COO
    +20
  • Trade size
    $101k at market
    +10
  • Share of holdings sold
    Sold 5.8% of holdings
    0
  • Cluster
    2 insiders selling within 14 days
    +8

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m 0.0%, 3m +9.1%, 6m -44.8%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

SPROOct 9, 2026 · close 1.20
Since filing Feb 5, 2026: -47.8%SPY +15.8% · excess -63.6%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-26-038441, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Feb 2, 2026AGrant or award
Common Stock
+68,000$0.00$0807,744Feb 5, 2026
Feb 2, 2026SOpen-market sale
Common Stock
-18,891$2.20$42k788,853Feb 5, 2026
Feb 3, 2026SOpen-market sale
Common Stock
-24,224$2.14$52k764,629Feb 5, 2026
Feb 4, 2026SOpen-market sale
Common Stock
-3,471$2.24$7,775761,158Feb 5, 2026
Feb 2, 2026AGrant or award
Stock Option (Right to Buy)derivative
+137,000$0.00$0137,000Feb 5, 2026

Related signals

Other insiders at Spero Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
34Weak
SPROsell 2
Spero Therapeutics, Inc.
Timothy Keutzer
Chief Operating Officer
$44k
18,652 shares
-2%
35Weak
SPROsell 2
Spero Therapeutics, Inc.
Esther Rajavelu
See Remarks
$207k
87,917 shares
-8%
29Weak
SPROsell 2
Spero Therapeutics, Inc.
Esther Rajavelu
See Remarks
$41k
18,442 shares
-2%
25Weak
SPROsell
Spero Therapeutics, Inc.
Esther Rajavelu
See Remarks
$95k
40,270 shares
-4%
28Weak
SPROsell 2
Spero Therapeutics, Inc.
Timothy Keutzer
Chief Operating Officer
$3,339
1,695 shares
-0%
23Weak
SPROsell 2
Spero Therapeutics, Inc.
Ankit Mahadevia
director
$13k
6,572 shares
-1%
26Weak
SPROsell
Spero Therapeutics, Inc.
Timothy Keutzer
Chief Operating Officer
$44k
56,537 shares
-7%
29Weak
SPROsell
Spero Therapeutics, Inc.
Esther Rajavelu
CFO & CBO
$53k
40,596 shares
-10%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Timothy Keutzer sold $101k of SPRO | InsiderTell