Insider · CIK 0001276128
Joseph Loscalzo
Files at IONS (IONIS PHARMACEUTICALS INC), CYPH (CYPHERPUNK TECHNOLOGIES INC.). First filing Nov 14, 2024, latest May 6, 2026.
Joseph Loscalzo files SEC Form 4 as director at IONS (IONIS PHARMACEUTICALS INC), and also at CYPH (CYPHERPUNK TECHNOLOGIES INC.). Since Nov 14, 2024, Joseph Loscalzo has reported 0 open-market buys worth $0 and 5 open-market sells worth $8.6M, the latest filed on May 6, 2026.
A track record needs three past buys with six months of prices behind them; Joseph Loscalzo has 0, so none is measured yet.
The newest scored trade: sold $5.8M of IONS on May 4, 2026, filed May 6, 2026, scored 40 (moderate), under a 10b5-1 plan. In the last 12 months: 0 buys worth $0 and 3 sells worth $7.1M.
Where the trades landed
Last year at the company this insider has traded most, with each buy and sell on the bar it happened.
IONS: IONIS PHARMACEUTICALS INC
Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™
Signals
This insider’s open-market buys and sells, scored.
| Score | Company | Value | Holdings | Price context | Filed |
|---|---|---|---|---|---|
| 40Moderate | IONIS PHARMACEUTICALS INC | $5.8M 77,289 shares | -68% | +137% from low-13% from high | |
| 4Weak | IONIS PHARMACEUTICALS INC | $83k 1,032 shares | -3% | +208% from low-9% from high | |
| 30Weak | IONIS PHARMACEUTICALS INC | $1.2M 16,000 shares | -31% | +191% from low0% from high | |
| 29Weak | IONIS PHARMACEUTICALS INC | $962k 16,000 shares | -31% | +137% from low0% from high | |
| 38Weak | IONIS PHARMACEUTICALS INC | $511k 13,508 shares | -30% | - |
Planned sales
Form 144 notices this insider filed before selling restricted or control stock, newest first.
| Filed | Company | Shares | Value | Sale date | Past 3 months |
|---|---|---|---|---|---|
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | 54,321 0.03% of outstanding | $4.3M | May 4, 2026 | $83k |
| Mar 3, 2026 | IONS IONIS PHARMACEUTICALS INC | 24,000 0.01% of outstanding | $1.9M | Mar 3, 2026 | none |
| Oct 31, 2025 | IONS IONIS PHARMACEUTICALS INC | 16,000 0.01% of outstanding | $1.2M | Oct 31, 2025 | $962k |
| Sep 3, 2025 | IONS IONIS PHARMACEUTICALS INC | 16,000 0.01% of outstanding | $962k | Sep 3, 2025 | none |
| Nov 12, 2024 | IONS IONIS PHARMACEUTICALS INC | 13,508 0.01% of outstanding | $525k | Nov 12, 2024 | none |
Transactions
Every row this insider has filed, 39 in all, newest first.
| Date | Company | Transaction | Shares | Price | Value | Holdings after | Filed |
|---|---|---|---|---|---|---|---|
| Jul 1, 2026 | IONS IONIS PHARMACEUTICALS INC | AGrant or award Non-Qualified Stock Option (right to buy)derivative | +5,369 | $0.00 | $0 | 5,369 | Jul 6, 2026 |
| Jul 1, 2026 | IONS IONIS PHARMACEUTICALS INC | AGrant or award Restricted Stock Unitderivative | +2,301 | $0.00 | $0 | 7,521 | Jul 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +10,968 | $38.06 | $417k | 47,298 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +12,000 | $40.05 | $481k | 59,298 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +10,321 | $41.08 | $424k | 69,619 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +16,000 | $42.88 | $686k | 85,619 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +12,000 | $60.20 | $722k | 97,619 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +16,000 | $64.80 | $1.0M | 113,619 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | SOpen-market sale Common Stock10b5-1 | -59,508 | $74.90 | $4.5M | 54,111 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | SOpen-market sale Common Stock10b5-1 | -17,781 | $75.58 | $1.3M | 36,330 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -10,968 | $0.00 | $0 | 0 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -12,000 | $0.00 | $0 | 0 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -10,321 | $0.00 | $0 | 0 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -16,000 | $0.00 | $0 | 0 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -12,000 | $0.00 | $0 | 0 | May 6, 2026 |
| May 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -16,000 | $0.00 | $0 | 0 | May 6, 2026 |
| Mar 13, 2026 | CYPH CYPHERPUNK TECHNOLOGIES INC. | MOption exercise Common Stock | +74,700 | - | - | 74,700 | Mar 17, 2026 |
| Mar 13, 2026 | CYPH CYPHERPUNK TECHNOLOGIES INC. | MOption exercise Common Stock | +94,050 | - | - | 168,750 | Mar 17, 2026 |
| Mar 13, 2026 | CYPH CYPHERPUNK TECHNOLOGIES INC. | MOption exercise Restricted Stock Unitsderivative | -74,700 | $0.00 | $0 | 0 | Mar 17, 2026 |
| Mar 13, 2026 | CYPH CYPHERPUNK TECHNOLOGIES INC. | MOption exercise Restricted Stock Unitsderivative | -94,050 | $0.00 | $0 | 0 | Mar 17, 2026 |
| Mar 3, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +832 | $38.06 | $32k | 37,162 | Mar 5, 2026 |
| Mar 3, 2026 | IONS IONIS PHARMACEUTICALS INC | SOpen-market sale Common Stock10b5-1 | -832 | $80.33 | $67k | 36,330 | Mar 5, 2026 |
| Mar 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +200 | $38.06 | $7,612 | 36,530 | Mar 5, 2026 |
| Mar 4, 2026 | IONS IONIS PHARMACEUTICALS INC | SOpen-market sale Common Stock10b5-1 | -200 | $80.00 | $16k | 36,330 | Mar 5, 2026 |
| Mar 3, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -832 | $0.00 | $0 | 11,168 | Mar 5, 2026 |
| Mar 4, 2026 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -200 | $0.00 | $0 | 10,968 | Mar 5, 2026 |
| Dec 23, 2025 | CYPH CYPHERPUNK TECHNOLOGIES INC. | AGrant or award Restricted Stock Unitsderivative | +94,050 | $0.00 | $0 | 94,050 | Dec 30, 2025 |
| Nov 11, 2025 | CYPH CYPHERPUNK TECHNOLOGIES INC. | AGrant or award Restricted Stock Unitsderivative | +74,700 | $0.00 | $0 | 74,700 | Nov 13, 2025 |
| Oct 31, 2025 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock10b5-1 | +16,000 | $52.22 | $836k | 52,330 | Nov 3, 2025 |
| Oct 31, 2025 | IONS IONIS PHARMACEUTICALS INC | SOpen-market sale Common Stock10b5-1 | -16,000 | $75.10 | $1.2M | 36,330 | Nov 3, 2025 |
| Oct 31, 2025 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative10b5-1 | -16,000 | $0.00 | $0 | 0 | Nov 3, 2025 |
| Sep 3, 2025 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock | +16,000 | $24.42 | $391k | 52,330 | Sep 4, 2025 |
| Sep 3, 2025 | IONS IONIS PHARMACEUTICALS INC | SOpen-market sale Common Stock10b5-1 | -16,000 | $60.15 | $962k | 36,330 | Sep 4, 2025 |
| Sep 3, 2025 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Non-Qualified Stock Option (right to buy)derivative | -16,000 | $0.00 | $0 | 0 | Sep 4, 2025 |
| Jul 15, 2025 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Common Stock | +4,079 | $0.00 | $0 | 36,330 | Jul 17, 2025 |
| Jul 15, 2025 | IONS IONIS PHARMACEUTICALS INC | MOption exercise Restricted Stock Unitderivative | -4,079 | $0.00 | $0 | 5,220 | Jul 17, 2025 |
| Jul 1, 2025 | IONS IONIS PHARMACEUTICALS INC | AGrant or award Non-Qualified Stock Option (right to buy)derivative | +11,518 | $0.00 | $0 | 11,518 | Jul 2, 2025 |
| Jul 1, 2025 | IONS IONIS PHARMACEUTICALS INC | AGrant or award Restricted Stock Unitderivative | +5,220 | $0.00 | $0 | 9,299 | Jul 2, 2025 |
| Nov 12, 2024 | IONS IONIS PHARMACEUTICALS INC | SOpen-market sale Common Stock10b5-1 | -13,508 | $37.86 | $511k | 32,251 | Nov 14, 2024 |
Questions about Joseph Loscalzo
Answered from the filings on this page, as of the latest one.
Is Joseph Loscalzo buying or selling?
In the last 12 months Joseph Loscalzo reported 0 open-market buys worth $0 and 3 open-market sells worth $7.1M on SEC Form 4; the latest was sold $5.8M of IONS on May 4, 2026. Grants, option exercises and tax withholding are not counted.
How did Joseph Loscalzo's past buys perform?
Not measured yet. InsiderTell needs three past buys with six months of prices to publish a track record, and Joseph Loscalzo has 0.
Where does Joseph Loscalzo file Form 4?
Joseph Loscalzo has filed Form 4 at IONS (IONIS PHARMACEUTICALS INC); CYPH (CYPHERPUNK TECHNOLOGIES INC.). A Form 4 is required of officers, directors and holders of more than 10% of a share class within two business days of a trade.
Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.