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Insider · CIK 0001564926

Patrick R. O'Neil

officer

Files at IONS (IONIS PHARMACEUTICALS INC). First filing Jan 17, 2025, latest Jun 30, 2026.

In brief

Patrick R. O'Neil files SEC Form 4 as officer at IONS (IONIS PHARMACEUTICALS INC). Since Jan 17, 2025, Patrick R. O'Neil has reported 0 open-market buys worth $0 and 14 open-market sells worth $17M, the latest filed on Jun 30, 2026.

A track record needs three past buys with six months of prices behind them; Patrick R. O'Neil has 0, so none is measured yet.

The newest scored trade: sold $246k of IONS on Jun 26, 2026, filed Jun 30, 2026, scored 23 (weak), under a 10b5-1 plan. In the last 12 months: 0 buys worth $0 and 4 sells worth $2.2M.

Track record
Not enough history
Fewer than three past buys with six months of prices.
Median 6-month excess
-
after past buys, n = 0
Hit rate
-
past buys that beat the index over 6 months
Open-market trades
0 / 14
$0 bought, $17M sold

Where the trades landed

Last year at the company this insider has traded most, with each buy and sell on the bar it happened.

IONS: IONIS PHARMACEUTICALS INC

IONSOct 9, 2026 · close 45.28

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

Signals

This insider’s open-market buys and sells, scored.

ScoreCompanyValueHoldingsPrice contextFiled
23Weak
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
$246k
3,069 shares
-5%+105% from low-6% from high
37Weak
IONSsell 1110b5-1
IONIS PHARMACEUTICALS INC
$764k
10,148 shares
-14%+195% from low-13% from high
48Moderate
IONSsell 12
IONIS PHARMACEUTICALS INC
$516k
6,179 shares
-8%+224% from low-1% from high
41Moderate
IONSsell 11
IONIS PHARMACEUTICALS INC
$697k
9,191 shares
-12%+199% from low-8% from high
24Weak
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
$937k
13,441 shares
-20%+171% from low-0% from high
40Moderate
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
$4.4M
64,664 shares
-74%+168% from low0% from high
30Weak
IONSsell 710b5-1
IONIS PHARMACEUTICALS INC
$1.6M
25,300 shares
-37%+151% from low-0% from high
5Weak
IONSsell 1210b5-1
IONIS PHARMACEUTICALS INC
$110k
1,700 shares
-3%+148% from low-2% from high
30Weak
IONSsell 1210b5-1
IONIS PHARMACEUTICALS INC
$1.4M
21,000 shares
-27%+152% from low0% from high
40Moderate
IONSsell 1310b5-1
IONIS PHARMACEUTICALS INC
$5.4M
89,900 shares
-128%+125% from low0% from high
1Weak
IONSsell10b5-1
IONIS PHARMACEUTICALS INC
$39k
1,207 shares
-2%-
22Weak
IONSsell 710b5-1
IONIS PHARMACEUTICALS INC
$195k
6,165 shares
-10%-
36Weak
IONSsell 7
IONIS PHARMACEUTICALS INC
$46k
1,406 shares
-2%-
33Weak
IONSsell 10
IONIS PHARMACEUTICALS INC
$242k
7,360 shares
-11%-

Planned sales

Form 144 notices this insider filed before selling restricted or control stock, newest first.

FiledCompanySharesValueSale datePast 3 months
Jun 26, 2026 IONS
IONIS PHARMACEUTICALS INC
3,069
0.00% of outstanding
$246kJun 26, 2026none
Mar 9, 2026 IONS
IONIS PHARMACEUTICALS INC
13,217
0.01% of outstanding
$995kMar 9, 2026$1.2M
Jan 30, 2026 IONS
IONIS PHARMACEUTICALS INC
6,179
0.00% of outstanding
$513kJan 30, 2026$697k
Jan 16, 2026 IONS
IONIS PHARMACEUTICALS INC
9,191
0.01% of outstanding
$701kJan 16, 2026none
Oct 2, 2025 IONS
IONIS PHARMACEUTICALS INC
78,105
0.05% of outstanding
$5.3MOct 2, 2025$8.5M
Sep 3, 2025 IONS
IONIS PHARMACEUTICALS INC
124,850
0.08% of outstanding
$7.6MSep 3, 2025$711k
Sep 2, 2025 IONS
IONIS PHARMACEUTICALS INC
13,050
0.01% of outstanding
$711kSep 2, 2025none
Feb 4, 2025 IONS
IONIS PHARMACEUTICALS INC
7,372
0.00% of outstanding
$237kFeb 4, 2025$67k
Jan 31, 2025 IONS
IONIS PHARMACEUTICALS INC
1,910
0.00% of outstanding
$67kJan 31, 2025$242k
Jan 16, 2025 IONS
IONIS PHARMACEUTICALS INC
7,360
0.00% of outstanding
$241kJan 16, 2025none
Dec 27, 2023 IONS
IONIS PHARMACEUTICALS INC
20,825
0.01% of outstanding
$1.1MDec 26, 2023none

Transactions

The newest 50 of 60 rows this insider has filed.

DateCompanyTransactionSharesPriceValueHoldings afterFiled
Aug 31, 2026IONS
IONIS PHARMACEUTICALS INC
JOther
Common Stock
+63$51.31$3,23259,20541 d ago
Jun 26, 2026IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-3,069$80.00$246k61,470Jun 30, 2026
Mar 9, 2026IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-10,148$75.25$764k62,211Mar 11, 2026
Feb 27, 2026IONS
IONIS PHARMACEUTICALS INC
JOther
Common Stock
+376$48.87$18k72,359Mar 3, 2026
Jan 29, 2026IONS
IONIS PHARMACEUTICALS INC
AGrant or award
Common Stock
+11,991$0.00$078,162Feb 2, 2026
Jan 30, 2026IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock
-6,179$83.53$516k71,983Feb 2, 2026
Jan 15, 2026IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock
+21,473$0.00$075,362Jan 20, 2026
Jan 16, 2026IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock
-9,191$75.84$697k66,171Jan 20, 2026
Jan 15, 2026IONS
IONIS PHARMACEUTICALS INC
AGrant or award
Performance Restricted Stock Unitsderivative
+25,800$0.00$090,601Jan 20, 2026
Jan 15, 2026IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Restricted Stock Unitderivative
-21,473$0.00$039,251Jan 20, 2026
Jan 15, 2026IONS
IONIS PHARMACEUTICALS INC
AGrant or award
Restricted Stock Unitderivative
+9,675$0.00$048,926Jan 20, 2026
Jan 2, 2026IONS
IONIS PHARMACEUTICALS INC
AGrant or award
Non-Qualified Stock Option (right to buy)derivative
+19,350$0.00$019,350Jan 6, 2026
Oct 6, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+10,200$52.87$539k67,330Oct 8, 2025
Oct 6, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-10,200$69.89$713k57,130Oct 8, 2025
Oct 6, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-3,241$69.27$224k53,889Oct 8, 2025
Oct 6, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-10,200$0.00$017,000Oct 8, 2025
Oct 2, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+30,203$56.78$1.7M87,333Oct 2, 2025
Oct 2, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-30,203$67.69$2.0M57,130Oct 2, 2025
Oct 2, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+34,461$60.89$2.1M91,591Oct 2, 2025
Oct 2, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-34,461$67.69$2.3M57,130Oct 2, 2025
Oct 2, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-30,203$0.00$00Oct 2, 2025
Oct 2, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-34,461$0.00$00Oct 2, 2025
Sep 29, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+10,473$56.78$595k67,603Oct 1, 2025
Sep 29, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-10,473$64.54$676k57,130Oct 1, 2025
Sep 30, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+14,827$56.78$842k71,957Oct 1, 2025
Sep 30, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-14,827$64.68$959k57,130Oct 1, 2025
Sep 29, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-10,473$0.00$045,030Oct 1, 2025
Sep 30, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-14,827$0.00$030,203Oct 1, 2025
Sep 12, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+1,700$56.78$97k58,830Sep 16, 2025
Sep 12, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-1,700$64.58$110k57,130Sep 16, 2025
Sep 12, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-1,700$0.00$055,503Sep 16, 2025
Sep 9, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+20,000$60.89$1.2M77,130Sep 11, 2025
Sep 9, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-20,000$64.56$1.3M57,130Sep 11, 2025
Sep 9, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+1,000$56.78$57k58,130Sep 11, 2025
Sep 9, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-1,000$64.56$65k57,130Sep 11, 2025
Sep 9, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-1,000$0.00$057,203Sep 11, 2025
Sep 9, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-20,000$0.00$034,461Sep 11, 2025
Sep 2, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+13,050$32.60$425k70,180Sep 4, 2025
Sep 2, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-13,050$54.51$711k57,130Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+14,000$37.58$526k71,130Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-65,475$60.89$4.0M5,655Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+13,050$32.60$425k18,705Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
SOpen-market sale
Common Stock10b5-1
-11,375$61.42$699k7,330Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Common Stock10b5-1
+49,800$53.77$2.7M57,130Sep 4, 2025
Sep 2, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-13,050$0.00$017,517Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-13,050$0.00$04,467Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-14,000$0.00$08,942Sep 4, 2025
Sep 3, 2025IONS
IONIS PHARMACEUTICALS INC
MOption exercise
Non-Qualified Stock Option (right to buy)derivative10b5-1
-49,800$0.00$00Sep 4, 2025
Aug 29, 2025IONS
IONIS PHARMACEUTICALS INC
JOther
Common Stock
+331$27.71$9,17257,130Sep 3, 2025
Feb 28, 2025IONS
IONIS PHARMACEUTICALS INC
JOther
Common Stock
+554$28.21$16k56,799Mar 4, 2025
50 of 60 rows shown.

Questions about Patrick R. O'Neil

Answered from the filings on this page, as of the latest one.

Is Patrick R. O'Neil buying or selling?

In the last 12 months Patrick R. O'Neil reported 0 open-market buys worth $0 and 4 open-market sells worth $2.2M on SEC Form 4; the latest was sold $246k of IONS on Jun 26, 2026. Grants, option exercises and tax withholding are not counted.

How did Patrick R. O'Neil's past buys perform?

Not measured yet. InsiderTell needs three past buys with six months of prices to publish a track record, and Patrick R. O'Neil has 0.

Where does Patrick R. O'Neil file Form 4?

Patrick R. O'Neil has filed Form 4 at IONS (IONIS PHARMACEUTICALS INC) as EVP CLO & General Counsel. A Form 4 is required of officers, directors and holders of more than 10% of a share class within two business days of a trade.

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.