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sellModerate cluster of 410b5-1 plan

Emily M. Leproust sold $56M of TWST

Chief Executive Officer at Twist Bioscience Corp. 356,546 shares at an average of $157.99, traded Sep 17, 2026, filed Sep 21, 2026.

Warning score
40
Value
$56M
356,546 shares
Holdings after
620,589
-36% from before
From 52-week low
+511%
low $25.45, close $155.56
From 52-week high
0%
high $155.56, as of Sep 17, 2026

Score components

  • Role
    CEO
    +25
  • Trade size
    $56.3M at market
    +25
  • Share of holdings sold
    Sold 36% of holdings
    +10
  • Cluster
    4 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

TWSTOct 9, 2026 · close 159.78
Since filing Sep 21, 2026: -3.6%SPY +0.7% · excess -4.3%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001214659-26-011832, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 17, 2026MOption exercise
Common Stock10b5-1
+133,269$26.66$3.6M901,69621 d ago
Sep 17, 2026MOption exercise
Common Stock10b5-1
+75,439$8.82$665k977,13521 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-2,440$151.46$370k974,69521 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-6,644$152.21$1.0M968,05121 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-3,399$153.40$521k964,65221 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-4,175$154.17$644k960,47721 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-13,378$155.46$2.1M947,09921 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-9,097$156.47$1.4M938,00221 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-32,260$157.49$5.1M905,74221 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-232,173$158.09$37M673,56921 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-23,884$159.53$3.8M649,68521 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-14,493$160.44$2.3M635,19221 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-11,169$161.49$1.8M624,02321 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-2,565$162.31$416k621,45821 d ago
Sep 17, 2026SOpen-market sale
Common Stock10b5-1
-869$163.39$142k620,58921 d ago
Sep 17, 2026MOption exercise
Employee Stock Option (right to buy)derivative10b5-1
-75,439$0.00$0021 d ago
Sep 17, 2026MOption exercise
Employee Stock Option (right to buy)derivative10b5-1
-133,269$0.00$0021 d ago

Related signals

Other insiders at Twist Bioscience Corp and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
44Moderate
TWSTsell 610b5-1
Twist Bioscience Corp
Emily M. Leproust
Chief Executive Officer
$919k
4,548 shares
-1%
60Notable
TWSTsell 6
Twist Bioscience Corp
Dennis Cho
See Remarks
$1.8M
9,514 shares
-13%
65Notable
TWSTsell 6
Twist Bioscience Corp
Patrick John Finn
President and COO
$4.9M
25,714 shares
-12%
55Moderate
TWSTsell 6
Twist Bioscience Corp
Paula Green
SVP of Human Resources
$1.9M
10,088 shares
-9%
62Notable
TWSTsell 6
Twist Bioscience Corp
Adam Laponis
Chief Financial Officer
$1.5M
8,057 shares
-7%
45Moderate
TWSTsell 610b5-1
Twist Bioscience Corp
Emily M. Leproust
Chief Executive Officer
$8.8M
46,391 shares
-8%
44Moderate
TWSTsell 6
Twist Bioscience Corp
Robert F. Werner
Chief Accounting Officer
$280k
1,482 shares
-3%
44Moderate
TWSTsell 610b5-1
Twist Bioscience Corp
Emily M. Leproust
Chief Executive Officer
$923k
5,203 shares
-1%
37Weak
TWSTsell 6
Twist Bioscience Corp
Dennis Cho
See Remarks
$58k
348 shares
-0%
37Weak
TWSTsell 6
Twist Bioscience Corp
Paula Green
SVP of Human Resources
$49k
294 shares
-0%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Emily M. Leproust sold $56M of TWST | InsiderTell