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sellWeak10b5-1 plan

Yvonne Greenstreet sold $16M of ALNY

Chief Executive Officer at ALNYLAM PHARMACEUTICALS, INC.. 50,937 shares at an average of $305.00, traded May 30, 2025, filed Jun 3, 2025.

Warning score
35
Value
$16M
50,937 shares
Holdings after
48,948
-63% from before
From 52-week low
+36%
low $224.32, close $304.56
From 52-week high
0%
high $304.56, as of May 30, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $15.5M at market
    +25
  • Share of holdings sold
    Sold 63% of holdings
    +20
  • Cluster
    No other insider selling within 14 days
    0
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ALNYOct 9, 2026 · close 232.68
Since filing Jun 3, 2025: -23.4%SPY +32.8% · excess -56.2%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001735276-25-000075, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
May 30, 2025MOption exercise
Common Stock10b5-1
+12,081$119.13$1.4M61,029Jun 3, 2025
May 30, 2025MOption exercise
Common Stock10b5-1
+19,559$118.05$2.3M80,588Jun 3, 2025
May 30, 2025SOpen-market sale
Common Stock10b5-1
-25,469$304.00$7.7M55,119Jun 3, 2025
May 30, 2025SOpen-market sale
Common Stock10b5-1
-6,171$306.00$1.9M48,948Jun 3, 2025
Jun 2, 2025MOption exercise
Common Stock10b5-1
+12,080$119.13$1.4M61,028Jun 3, 2025
Jun 2, 2025MOption exercise
Common Stock10b5-1
+7,217$118.05$852k68,245Jun 3, 2025
Jun 2, 2025SOpen-market sale
Common Stock10b5-1
-19,297$306.00$5.9M48,948Jun 3, 2025
May 30, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-19,559$0.00$08,064Jun 3, 2025
Jun 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-7,217$0.00$0847Jun 3, 2025
May 30, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-12,081$0.00$012,919Jun 3, 2025
Jun 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-12,080$0.00$0839Jun 3, 2025

Related signals

Other insiders at ALNYLAM PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
36Weak
ALNYsell
ALNYLAM PHARMACEUTICALS, INC.
Bryan Supran
EVP, CLO and Secretary
$399k
1,758 shares
-12%
23Weak
ALNYsell 210b5-1
ALNYLAM PHARMACEUTICALS, INC.
Kevin Joseph Fitzgerald
CSO & EVP, Head of Research
$5.5M
12,128 shares
-36%
33Weak
ALNYsell 210b5-1
ALNYLAM PHARMACEUTICALS, INC.
Yvonne Greenstreet
Chief Executive Officer
$12M
25,650 shares
-32%
40Moderate
ALNYsell 510b5-1
ALNYLAM PHARMACEUTICALS, INC.
Pushkal Garg
EVP Chief R&D
$2.7M
5,959 shares
-23%
55Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Kevin Joseph Fitzgerald
CSO & EVP, Head of Research
$1.1M
2,441 shares
-9%
50Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Tolga Tanguler
EVP, Chief Commercial Officer
$635k
1,405 shares
-5%
70Notable
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Yvonne Greenstreet
Chief Executive Officer
$4.0M
8,924 shares
-12%
62Notable
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Jeffrey V. Poulton
EVP, Chief Financial Officer
$1.7M
3,821 shares
-7%
33Weak
ALNYsell 210b5-1
ALNYLAM PHARMACEUTICALS, INC.
Colleen F Reitan
director
$8.4M
18,000 shares
-96%
40Moderate
ALNYsell 710b5-1
ALNYLAM PHARMACEUTICALS, INC.
Tolga Tanguler
EVP, Chief Commercial Officer
$1.6M
3,474 shares
-12%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Yvonne Greenstreet sold $16M of ALNY | InsiderTell