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sellWeak cluster of 210b5-1 plan

Pamela J. Cramer sold $458k of RYTM

Chief Human Resources Officer at RHYTHM PHARMACEUTICALS, INC.. 7,031 shares at an average of $65.09, traded Apr 29, 2025, filed May 1, 2025.

Warning score
15
Value
$458k
7,031 shares
Holdings after
19,209
-27% from before
From 52-week low
+39%
low $46.95, close $65.22
From 52-week high
-3%
high $67.33, as of Apr 29, 2025

Score components

  • Role
    Officer
    +15
  • Trade size
    $458k at market
    +17
  • Share of holdings sold
    Sold 27% of holdings
    +10
  • Cluster
    2 insiders selling within 14 days
    +8
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

RYTMOct 9, 2026 · close 90.78
Since filing May 1, 2025: +42.3%SPY +41.7% · excess +0.6%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001104659-25-043557, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Apr 29, 2025MOption exercise
Common Stock10b5-1
+7,031$6.80$48k26,240May 1, 2025
Apr 29, 2025SOpen-market sale
Common Stock10b5-1
-7,031$65.09$458k19,209May 1, 2025
Apr 29, 2025MOption exercise
Stock Options (Right to Buy)derivative10b5-1
-7,031$0.00$035,159May 1, 2025

Related signals

Other insiders at RHYTHM PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
28Weak
RYTMsell 210b5-1
RHYTHM PHARMACEUTICALS, INC.
David P Meeker
President and CEO
$5.1M
50,000 shares
-17%
30Weak
RYTMsell 210b5-1
RHYTHM PHARMACEUTICALS, INC.
Hunter C Smith
Chief Financial Officer
$6.6M
62,774 shares
-36%
19Weak
RYTMsell 210b5-1
RHYTHM PHARMACEUTICALS, INC.
Christopher Paul German
Corporate Controller & CAO
$143k
1,500 shares
-62%
0Weak
RYTMsell 210b5-1
RHYTHM PHARMACEUTICALS, INC.
Pamela J. Cramer
Chief Human Resources Officer
$131k
1,520 shares
-7%
30Weak
RYTMsell 310b5-1
RHYTHM PHARMACEUTICALS, INC.
Pamela J. Cramer
Chief Human Resources Officer
$1.2M
15,572 shares
-45%
29Weak
RYTMsell 310b5-1
RHYTHM PHARMACEUTICALS, INC.
Christopher Paul German
Corporate Controller & CAO
$308k
3,817 shares
-81%
14Weak
RYTMsell 310b5-1
RHYTHM PHARMACEUTICALS, INC.
Alastair Garfield
Chief Scientific Officer
$85k
1,319 shares
-30%
26Weak
RYTMsell 510b5-1
RHYTHM PHARMACEUTICALS, INC.
Christopher Paul German
Corporate Controller & CAO
$139k
2,069 shares
-52%
23Weak
RYTMsell 510b5-1
RHYTHM PHARMACEUTICALS, INC.
Pamela J. Cramer
Chief Human Resources Officer
$478k
7,031 shares
-27%
40Moderate
RYTMsell 510b5-1
RHYTHM PHARMACEUTICALS, INC.
David W J McGirr
director
$4.3M
65,431 shares
-96%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Pamela J. Cramer sold $458k of RYTM | InsiderTell