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sellModerate cluster of 710b5-1 plan

Dennis A Ausiello sold $14M of ALNY

director at ALNYLAM PHARMACEUTICALS, INC.. 31,448 shares at an average of $436.58, traded Aug 14, 2025, filed Aug 15, 2025.

Warning score
40
Value
$14M
31,448 shares
Holdings after
911
-97% from before
From 52-week low
+97%
low $224.32, close $442.73
From 52-week high
0%
high $442.73, as of Aug 14, 2025

Score components

  • Role
    Director
    +15
  • Trade size
    $13.7M at market
    +25
  • Share of holdings sold
    Sold 97% of holdings
    +20
  • Cluster
    7 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ALNYOct 9, 2026 · close 232.68
Since filing Aug 15, 2025: -48.2%SPY +22.6% · excess -70.8%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001735276-25-000079, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Aug 14, 2025MOption exercise
Common Stock10b5-1
+9,000$72.01$648k9,911Aug 15, 2025
Aug 14, 2025MOption exercise
Common Stock10b5-1
+5,153$128.31$661k15,064Aug 15, 2025
Aug 14, 2025MOption exercise
Common Stock10b5-1
+4,581$148.77$682k19,645Aug 15, 2025
Aug 14, 2025MOption exercise
Common Stock10b5-1
+5,228$151.22$791k24,873Aug 15, 2025
Aug 14, 2025MOption exercise
Common Stock10b5-1
+4,032$171.95$693k28,905Aug 15, 2025
Aug 14, 2025MOption exercise
Common Stock10b5-1
+3,454$189.87$656k32,359Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-1,985$430.81$855k30,374Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-1,938$432.94$839k28,436Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-2,098$434.50$912k26,338Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-7,675$435.40$3.3M18,663Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-5,358$436.00$2.3M13,305Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-1,922$437.56$841k11,383Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-2,086$438.34$914k9,297Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-5,302$439.27$2.3M3,995Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-1,238$440.54$545k2,757Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-1,205$441.88$532k1,552Aug 15, 2025
Aug 14, 2025SOpen-market sale
Common Stock10b5-1
-641$442.66$284k911Aug 15, 2025
Aug 14, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-9,000$0.00$00Aug 15, 2025
Aug 14, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-5,153$0.00$00Aug 15, 2025
Aug 14, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-4,581$0.00$00Aug 15, 2025
Aug 14, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-5,228$0.00$00Aug 15, 2025
Aug 14, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-4,032$0.00$00Aug 15, 2025
Aug 14, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-3,454$0.00$00Aug 15, 2025

Related signals

Other insiders at ALNYLAM PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
36Weak
ALNYsell
ALNYLAM PHARMACEUTICALS, INC.
Bryan Supran
EVP, CLO and Secretary
$399k
1,758 shares
-12%
26Weak
ALNYsell 510b5-1
ALNYLAM PHARMACEUTICALS, INC.
Kevin Joseph Fitzgerald
CSO & EVP, Head of Research
$418k
1,291 shares
-6%
51Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Tolga Tanguler
EVP, Chief Commercial Officer
$746k
2,309 shares
-6%
59Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Jeffrey V. Poulton
EVP, Chief Financial Officer
$797k
2,468 shares
-4%
64Notable
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Yvonne Greenstreet
Chief Executive Officer
$948k
2,933 shares
-3%
40Moderate
ALNYsell 510b5-1
ALNYLAM PHARMACEUTICALS, INC.
Pushkal Garg
EVP Chief R&D
$1.5M
4,713 shares
-20%
65Notable
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Yvonne Greenstreet
Chief Executive Officer
$2.2M
6,799 shares
-6%
48Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Tolga Tanguler
EVP, Chief Commercial Officer
$524k
1,598 shares
-4%
40Moderate
ALNYsell 510b5-1
ALNYLAM PHARMACEUTICALS, INC.
Kevin Joseph Fitzgerald
CSO & EVP, Head of Research
$1.1M
3,250 shares
-13%
40Moderate
ALNYsell 510b5-1
ALNYLAM PHARMACEUTICALS, INC.
Pushkal Garg
EVP Chief R&D
$1.1M
3,492 shares
-13%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Dennis A Ausiello sold $14M of ALNY | InsiderTell