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buyModerate cluster of 4

ARCH Venture Partners X, LLC bought $10.0M of PRME

owner at Prime Medicine, Inc.. 3,030,300 shares at an average of $3.30, traded Aug 1, 2025, filed Aug 1, 2025.

Conviction score
57
Value
$10.0M
3,030,300 shares
Holdings after
6,230,300
+95% from before
From 52-week low
-
no price yet
From 52-week high
-
no price yet

Score components

  • Role
    10% owner
    +12
  • Trade size
    $10.0M at market
    +25
  • Relative to holdings
    Holdings up 95%
    +10
  • Price context
    No price history yet
    0
  • Cluster
    4 insiders buying within 14 days
    +15
  • Repeat buying
    First buy in 90 days
    0
  • Track record
    Too few past buys to judge (0 with prices)
    0
  • Outside holder
    A 10% owner who is not an officer or director
    -5

What happened after comparable buys

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

PRMEOct 9, 2026 · close 3.99
Since filing Aug 1, 2025: -1.2%SPY +26.9% · excess -28.2%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001062993-25-013460, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Aug 1, 2025POpen-market purchase
Common Stockindirect: By ARCH Venture Fund XII, L.P.
+3,030,300$3.30$10.0M6,230,300Aug 1, 2025

Related signals

Other insiders at Prime Medicine, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
57Moderate
PRMEbuy 4
Prime Medicine, Inc.
Gv 2021 Gp, L.l.c.
owner
$5.0M
1,500,000 shares
+85%
57Moderate
PRMEbuy 4
Prime Medicine, Inc.
ARCH Venture Partners XII, LLC
owner
$10.0M
3,030,300 shares
+95%
65Notable
PRMEbuy 4
Prime Medicine, Inc.
Robert Nelsen
director, owner
$10.0M
3,030,300 shares
+95%
0Weak
PRMEbuy10b5-1
Prime Medicine, Inc.
David R. Liu
owner
$53k
21,000 shares
+0%
0Weak
PRMEbuy10b5-1
Prime Medicine, Inc.
David R. Liu
owner
$45k
21,000 shares
+0%
0Weak
PRMEbuy10b5-1
Prime Medicine, Inc.
David R. Liu
owner
$31k
21,000 shares
+0%
0Weak
PRMEbuy10b5-1
Prime Medicine, Inc.
David R. Liu
owner
$34k
21,000 shares
+0%
38Weak
PRMEbuy 3
Prime Medicine, Inc.
Richard Brudnick
Chief Business Officer
$24k
20,000 shares
-
48Moderate
PRMEbuy 3
Prime Medicine, Inc.
Ann L. Lee
Chief Technical Officer
$113k
100,000 shares
-
59Moderate
PRMEbuy 3
Prime Medicine, Inc.
Allan Reine
Chief Executive Officer
$147k
125,000 shares
-

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

ARCH Venture Partners X, LLC bought $10.0M of PRME | InsiderTell