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sellWeak cluster of 410b5-1 plan

Mark E Saad sold $1.1M of AXSM

director at Axsome Therapeutics, Inc.. 9,127 shares at an average of $125.07, traded Sep 5, 2025, filed Sep 5, 2025.

Warning score
30
Value
$1.1M
9,127 shares
Holdings after
10,002
-48% from before
From 52-week low
+56%
low $80.05, close $125.17
From 52-week high
-9%
high $137.75, as of Sep 5, 2025

Score components

  • Role
    Director
    +15
  • Trade size
    $1.1M at market
    +25
  • Share of holdings sold
    Sold 48% of holdings
    +10
  • Cluster
    4 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -3.9%, 3m +19.2%, 6m +29.7%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

AXSMOct 9, 2026 · close 168.35
Since filing Sep 5, 2025: +34.5%SPY +21.9% · excess +12.6%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000950170-25-113311, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 5, 2025MOption exercise
Common Stock10b5-1
+9,127$9.00$82k19,129Sep 5, 2025
Sep 5, 2025SOpen-market sale
Common Stock10b5-1
-9,127$125.07$1.1M10,002Sep 5, 2025
Sep 5, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-9,127$0.00$00Sep 5, 2025

Related signals

Other insiders at Axsome Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
30Weak
AXSMsell10b5-1
Axsome Therapeutics, Inc.
Mark L. Jacobson
Chief Operating Officer
$2.1M
10,000 shares
-100%
21Weak
AXSMsell 510b5-1
Axsome Therapeutics, Inc.
Roger Jeffs
director
$142k
572 shares
-1%
6Weak
AXSMsell 510b5-1
Axsome Therapeutics, Inc.
Mark Coleman
director
$160k
643 shares
-2%
16Weak
AXSMsell 510b5-1
Axsome Therapeutics, Inc.
Susan Mahony
director
$145k
600 shares
-42%
37Weak
AXSMsell 510b5-1
Axsome Therapeutics, Inc.
Nick Pizzie
Chief Financial Officer
$7.9M
33,000 shares
-43%
50Moderate
AXSMsell 510b5-1
Axsome Therapeutics, Inc.
Herriot Tabuteau
Chief Executive Officer
$12M
49,670 shares
-87%
45Moderate
AXSMsell 510b5-1
Axsome Therapeutics, Inc.
Mark Coleman
director
$4.0M
17,537 shares
-37%
38Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Mark L. Jacobson
Chief Operating Officer
$1.1M
4,750 shares
-105%
33Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Ari Maizel
Chief Commercial Officer
$1.4M
7,500 shares
-100%
38Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Mark L. Jacobson
Chief Operating Officer
$5.7M
35,378 shares
-100%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Mark E Saad sold $1.1M of AXSM | InsiderTell