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sellWeak cluster of 210b5-1 plan

Mark L. Jacobson sold $1.2M of AXSM

Chief Operating Officer at Axsome Therapeutics, Inc.. 10,000 shares at an average of $115.96, traded Sep 22, 2025, filed Sep 22, 2025.

Warning score
38
Value
$1.2M
10,000 shares
Holdings after
0
-100% from before
From 52-week low
+47%
low $80.05, close $117.49
From 52-week high
-15%
high $137.75, as of Sep 22, 2025

Score components

  • Role
    COO
    +20
  • Trade size
    $1.2M at market
    +25
  • Share of holdings sold
    Sold 100% of holdings
    +20
  • Cluster
    2 insiders selling within 14 days
    +8
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

AXSMOct 9, 2026 · close 168.35
Since filing Sep 22, 2025: +43.3%SPY +18.0% · excess +25.3%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-211788, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 22, 2025MOption exercise
Common Stock10b5-1
+10,000$2.85$29k10,000Sep 22, 2025
Sep 22, 2025SOpen-market sale
Common Stock10b5-1
-10,000$115.96$1.2M0Sep 22, 2025
Sep 22, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-10,000$0.00$035,378Sep 22, 2025

Related signals

Other insiders at Axsome Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
30Weak
AXSMsell10b5-1
Axsome Therapeutics, Inc.
Mark L. Jacobson
Chief Operating Officer
$2.1M
10,000 shares
-100%
45Moderate
AXSMsell 410b5-1
Axsome Therapeutics, Inc.
Mark L. Jacobson
Chief Operating Officer
$5.2M
45,783 shares
-792%
50Moderate
AXSMsell 410b5-1
Axsome Therapeutics, Inc.
Herriot Tabuteau
Chief Executive Officer
$7.4M
62,880 shares
-179%
27Weak
AXSMbuy
Axsome Therapeutics, Inc.
Mark Coleman
director
$200k
1,575 shares
+3%
30Weak
AXSMsell 410b5-1
Axsome Therapeutics, Inc.
Mark E Saad
director
$1.1M
9,127 shares
-48%
40Moderate
AXSMsell 410b5-1
Axsome Therapeutics, Inc.
Roger Jeffs
director
$1.7M
13,464 shares
-19%
38Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Roger Jeffs
director
$7.3M
60,000 shares
-46%
33Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Roger Jeffs
director
$4.4M
36,694 shares
-22%
33Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Hunter R. Murdock
General Counsel
$1.4M
13,514 shares
-180%
33Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Hunter R. Murdock
General Counsel
$2.3M
22,500 shares
-300%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Mark L. Jacobson sold $1.2M of AXSM | InsiderTell