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buyNotable cluster of 2

Perceptive Advisors LLC bought $1.9M of OBIO

owner at Orchestra BioMed Holdings, Inc.. 700,000 shares at an average of $2.75, traded Aug 1, 2025, filed Aug 5, 2025.

Conviction score
61
Value
$1.9M
700,000 shares
Holdings after
5,292,556
+15% from before
From 52-week low
+1%
low $2.42, close $2.44
From 52-week high
-62%
high $6.36, as of Aug 1, 2025

Score components

  • Role
    10% owner
    +12
  • Trade size
    $1.9M at market
    +25
  • Relative to holdings
    Holdings up 15%
    +3
  • Price context
    1% above the 52-week low; 62% below the 52-week high
    +18
  • Cluster
    2 insiders buying within 14 days
    +8
  • Repeat buying
    First buy in 90 days
    0
  • Track record
    Too few past buys to judge (0 with prices)
    0
  • Outside holder
    A 10% owner who is not an officer or director
    -5

What happened after comparable buys

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m +2.6%, 3m +40.1%, 6m +52.8%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

OBIOOct 12, 2026 · close 5.91
Since filing Aug 5, 2025: +121.3%SPY +25.6% · excess +95.8%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000950170-25-102537, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Aug 1, 2025POpen-market purchase
Common Stockindirect: See Footnote
+700,000$2.75$1.9M5,292,556Aug 5, 2025
Aug 1, 2025POpen-market purchase
Pre-funded Warrants (right to buy)derivativeindirect: See footnote
+1,500,000$2.75$4.1M1,500,000Aug 5, 2025

Related signals

Other insiders at Orchestra BioMed Holdings, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
5Weak
OBIOsell10b5-1
Orchestra BioMed Holdings, Inc.
Darren Sherman
See Remarks
$95k
15,000 shares
-1%
34Weak
OBIObuy 2
Orchestra BioMed Holdings, Inc.
David P Hochman
See Remarks
$48k
10,000 shares
+1%
3Weak
OBIOsell10b5-1
Orchestra BioMed Holdings, Inc.
Darren Sherman
See Remarks
$74k
15,000 shares
-1%
31Weak
OBIObuy 2
Orchestra BioMed Holdings, Inc.
Darren Sherman
See Remarks
$11k
2,000 shares
-
2Weak
OBIOsell10b5-1
Orchestra BioMed Holdings, Inc.
Darren Sherman
See Remarks
$61k
15,000 shares
-1%
3Weak
OBIOsell10b5-1
Orchestra BioMed Holdings, Inc.
Darren Sherman
See Remarks
$64k
15,000 shares
-1%
32Weak
OBIObuy 2
Orchestra BioMed Holdings, Inc.
David P Hochman
See Remarks
$19k
5,000 shares
+0%
2Weak
OBIOsell10b5-1
Orchestra BioMed Holdings, Inc.
Darren Sherman
See Remarks
$58k
15,000 shares
-1%
34Weak
OBIObuy 3
Orchestra BioMed Holdings, Inc.
Jason Aryeh
director
$2,494
665 shares
+1%
47Moderate
OBIObuy 3
Orchestra BioMed Holdings, Inc.
Jason Aryeh
director
$35k
8,971 shares
+8%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Perceptive Advisors LLC bought $1.9M of OBIO | InsiderTell