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sellModerate cluster of 510b5-1 plan

Martina Flammer M.D. sold $27M of INSM

Chief Medical Officer at INSMED Inc. 186,648 shares at an average of $144.34, traded Sep 2, 2025, filed Sep 4, 2025.

Warning score
40
Value
$27M
186,648 shares
Holdings after
83,111
-69% from before
From 52-week low
+124%
low $64.81, close $145.30
From 52-week high
0%
high $145.30, as of Sep 2, 2025

Score components

  • Role
    Officer
    +15
  • Trade size
    $26.9M at market
    +25
  • Share of holdings sold
    Sold 69% of holdings
    +20
  • Cluster
    5 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m +10.3%, 3m +43.9%, 6m +0.7%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

INSMOct 12, 2026 · close 98.56
Since filing Sep 4, 2025: -30.8%SPY +21.5% · excess -52.3%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001796960-25-000004, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 2, 2025MOption exercise
Common Stock10b5-1
+13,680$34.03$466k96,791Sep 4, 2025
Sep 2, 2025MOption exercise
Common Stock10b5-1
+17,160$26.46$454k113,951Sep 4, 2025
Sep 2, 2025MOption exercise
Common Stock10b5-1
+25,710$26.43$680k139,661Sep 4, 2025
Sep 2, 2025MOption exercise
Common Stock10b5-1
+38,846$17.07$663k178,507Sep 4, 2025
Sep 2, 2025MOption exercise
Common Stock10b5-1
+13,072$19.74$258k191,579Sep 4, 2025
Sep 2, 2025MOption exercise
Common Stock10b5-1
+36,555$18.95$693k228,134Sep 4, 2025
Sep 2, 2025MOption exercise
Common Stock10b5-1
+23,835$29.13$694k251,969Sep 4, 2025
Sep 2, 2025MOption exercise
Common Stock10b5-1
+17,790$25.83$460k269,759Sep 4, 2025
Sep 2, 2025SOpen-market sale
Common Stock10b5-1
-19,066$141.27$2.7M250,693Sep 4, 2025
Sep 2, 2025SOpen-market sale
Common Stock10b5-1
-5,877$142.03$835k244,816Sep 4, 2025
Sep 2, 2025SOpen-market sale
Common Stock10b5-1
-35,245$143.16$5.0M209,571Sep 4, 2025
Sep 2, 2025SOpen-market sale
Common Stock10b5-1
-28,063$144.05$4.0M181,508Sep 4, 2025
Sep 2, 2025SOpen-market sale
Common Stock10b5-1
-63,782$145.33$9.3M117,726Sep 4, 2025
Sep 2, 2025SOpen-market sale
Common Stock10b5-1
-34,615$146.05$5.1M83,111Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-13,680$0.00$00Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-17,160$0.00$00Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-25,710$0.00$08,570Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-38,846$0.00$025,898Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-13,072$0.00$013,073Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-36,555$0.00$073,110Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-23,835$0.00$039,725Sep 4, 2025
Sep 2, 2025MOption exercise
Stock Option (right to buy)derivative10b5-1
-17,790$0.00$053,370Sep 4, 2025

Related signals

Other insiders at INSMED Inc and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
50Moderate
INSMsell
INSMED Inc
David R Brennan
director
$3.1M
25,000 shares
-39%
70Notable
INSMsell 3
INSMED Inc
Melvin Sharoky Md
director
$638k
5,000 shares
-100%
65Notable
INSMsell 3
INSMED Inc
Roger Adsett
Chief Operating Officer
$32M
239,850 shares
-71%
30Weak
INSMsell 410b5-1
INSMED Inc
Martina Flammer M.D.
Chief Medical Officer
$3.5M
27,173 shares
-31%
23Weak
INSMsell 210b5-1
INSMED Inc
William Lewis
Chair and CEO
$1.1M
10,700 shares
-4%
23Weak
INSMsell 210b5-1
INSMED Inc
William Lewis
Chair and CEO
$1.3M
10,699 shares
-4%
25Weak
INSMsell 310b5-1
INSMED Inc
Martina Flammer M.D.
Chief Medical Officer
$1.4M
12,302 shares
-17%
30Weak
INSMsell 310b5-1
INSMED Inc
William Lewis
Chair and CEO
$2.2M
21,398 shares
-8%
21Weak
INSMsell 310b5-1
INSMED Inc
Michael Alexander Smith
Chief Legal Officer
$173k
1,806 shares
-5%
40Moderate
INSMsell 510b5-1
INSMED Inc
William Lewis
Chair and CEO
$613k
6,515 shares
-2%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Martina Flammer M.D. sold $27M of INSM | InsiderTell