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sellWeak cluster of 6

Stuart Poulton sold $2,578 of KPTI

EVP, Chief Development Officer at Karyopharm Therapeutics Inc.. 401 shares at an average of $6.43, traded Sep 15, 2025, filed Sep 16, 2025.

Warning score
30
Value
$2,578
401 shares
Holdings after
27,710
-1% from before
From 52-week low
+77%
low $3.54, close $6.26
From 52-week high
-58%
high $14.85, as of Sep 15, 2025

Score components

  • Role
    Officer
    +15
  • Trade size
    $3k at market
    0
  • Share of holdings sold
    Sold 1.4% of holdings
    0
  • Cluster
    6 insiders selling within 14 days
    +15

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -3.7%, 3m +1.1%, 6m +33.9%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

KPTIOct 12, 2026 · close 0.50
Since filing Sep 16, 2025: -91.9%SPY +19.5% · excess -111.4%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-205046, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 12, 2025AGrant or award
Common Stock
+888$0.00$028,111Sep 16, 2025
Sep 15, 2025SOpen-market sale
Common Stock
-401$6.43$2,57827,710Sep 16, 2025

Related signals

Other insiders at Karyopharm Therapeutics Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
KPTIsell
Karyopharm Therapeutics Inc.
Kristin Abate
Chief Accounting Officer
$450
378 shares
-2%
15Weak
KPTIsell
Karyopharm Therapeutics Inc.
Kristin Abate
Chief Accounting Officer
$38
19 shares
-0%
15Weak
KPTIsell
Karyopharm Therapeutics Inc.
Stuart Poulton
EVP, Chief Development Officer
$1,342
189 shares
-0%
30Weak
KPTIsell 6
Karyopharm Therapeutics Inc.
Kristin Abate
Chief Accounting Officer
$504
53 shares
-0%
30Weak
KPTIsell 6
Karyopharm Therapeutics Inc.
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
$3,078
324 shares
-0%
30Weak
KPTIsell 6
Karyopharm Therapeutics Inc.
Michael Mano
EVP, CLO&Secretary
$2,527
266 shares
-0%
40Moderate
KPTIsell 6
Karyopharm Therapeutics Inc.
Richard A. Paulson
President and CEO
$21k
2,203 shares
-1%
30Weak
KPTIsell 6
Karyopharm Therapeutics Inc.
Reshma Rangwala
EVP & Chief Medical Officer
$3,876
408 shares
-1%
30Weak
KPTIsell 6
Karyopharm Therapeutics Inc.
Stuart Poulton
EVP, Chief Development Officer
$3,829
403 shares
-0%
15Weak
KPTIsell
Karyopharm Therapeutics Inc.
Reshma Rangwala
EVP & Chief Medical Officer
$4,014
449 shares
-1%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Stuart Poulton sold $2,578 of KPTI | InsiderTell