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buyNotable cluster of 2

Reshma Kewalramani bought $3.9M of VRTX

CEO & President at VERTEX PHARMACEUTICALS INC / MA. 10,000 shares at an average of $389.58, traded Aug 6, 2025, filed Aug 7, 2025.

Conviction score
75
Value
$3.9M
10,000 shares
Holdings after
115,968
+9% from before
From 52-week low
+3%
low $374.98, close $385.65
From 52-week high
-25%
high $516.74, as of Aug 6, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $3.9M at market
    +25
  • Relative to holdings
    Holdings up 9%
    +3
  • Price context
    3% above the 52-week low; 25% below the 52-week high
    +14
  • Cluster
    2 insiders buying within 14 days
    +8
  • Repeat buying
    First buy in 90 days
    0
  • Track record
    Too few past buys to judge (0 with prices)
    0

What happened after comparable buys

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m +5.5%, 3m +10.8%, 6m +22.1%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

VRTXOct 13, 2026 · close 485.22
Since filing Aug 7, 2025: +29.2%SPY +24.7% · excess +4.4%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000875320-25-000220, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Aug 6, 2025POpen-market purchase
Common Stock
+4,290$389.08$1.7M110,258Aug 7, 2025
Aug 6, 2025POpen-market purchase
Common Stock
+5,710$389.95$2.2M115,968Aug 7, 2025

Related signals

Other insiders at VERTEX PHARMACEUTICALS INC / MA and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
37Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Duncan McKechnie
EVP, Chief Commercial Officer
$800k
1,541 shares
-12%
32Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Ourania Tatsis
EVP, Chief Reg. & Quality Off.
$787k
1,500 shares
-3%
26Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Joy Liu
EVP and Chief Legal Officer
$416k
828 shares
-4%
24Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$288k
596 shares
-4%
27Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$471k
1,020 shares
-6%
33Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.8M
4,062 shares
-19%
25Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$785k
1,745 shares
-8%
18Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Joy Liu
EVP and Chief Legal Officer
$364k
828 shares
-4%
33Weak
VRTXsell 310b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$888k
1,974 shares
-8%
30Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$614k
1,354 shares
-5%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.