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buyModerate

Baker Bros. Advisors LP bought $172M of KYMR

director, owner at Kymera Therapeutics, Inc.. 2,005,813 shares at an average of $86.00, traded Dec 11, 2025, filed Dec 11, 2025.

Conviction score
50
Value
$172M
2,005,813 shares
Holdings after
7,955,916
+376% from before
From 52-week low
+317%
low $21.05, close $87.81
From 52-week high
-7%
high $94.30, as of Dec 11, 2025

Score components

  • Role
    Director
    +15
  • Trade size
    $172.5M at market
    +25
  • Relative to holdings
    Holdings up 376%
    +10
  • Price context
    Near the top of the 52-week range
    0
  • Cluster
    No other insider buying within 14 days
    0
  • Repeat buying
    First buy in 90 days
    0
  • Track record
    Too few past buys to judge (0 with prices)
    0

What happened after comparable buys

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

KYMROct 9, 2026 · close 112.40
Since filing Dec 11, 2025: +28.0%SPY +14.2% · excess +13.8%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-315999, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 11, 2025POpen-market purchase
Common Stockindirect: See Footnotes
+167,192$86.00$14M701,326Dec 11, 2025
Dec 11, 2025POpen-market purchase
Common Stockindirect: See Footnotes
+1,838,621$86.00$158M7,955,916Dec 11, 2025

Related signals

Other insiders at Kymera Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
KYMRsell10b5-1
Kymera Therapeutics, Inc.
Nello Mainolfi
Chief Executive Officer
$3.4M
30,000 shares
-4%
41Moderate
KYMRsell
Kymera Therapeutics, Inc.
Brian Adams
Chief Legal Officer
$744k
6,371 shares
-11%
38Weak
KYMRsell 210b5-1
Kymera Therapeutics, Inc.
Jeremy G Chadwick
Chief Operating Officer
$9.0M
115,977 shares
-76%
20Weak
KYMRsell 210b5-1
Kymera Therapeutics, Inc.
Pamela Esposito
director
$198k
2,500 shares
-100%
35Weak
KYMRsell 410b5-1
Kymera Therapeutics, Inc.
Jeremy G Chadwick
Chief Operating Officer
$2.1M
25,758 shares
-27%
35Weak
KYMRsell 410b5-1
Kymera Therapeutics, Inc.
Bruce Booth
director
$7.4M
81,866 shares
-2%
53Moderate
KYMRsell 4
Kymera Therapeutics, Inc.
Jeremy G Chadwick
Chief Operating Officer
$516k
5,958 shares
-7%
54Moderate
KYMRsell 4
Kymera Therapeutics, Inc.
Jared Gollob
Chief Medical Officer
$917k
10,508 shares
-8%
27Weak
KYMRsell 410b5-1
Kymera Therapeutics, Inc.
Pamela Esposito
director
$218k
2,500 shares
-100%
15Weak
KYMRsell10b5-1
Kymera Therapeutics, Inc.
Pamela Esposito
director
$374k
5,500 shares
-100%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Baker Bros. Advisors LP bought $172M of KYMR | InsiderTell