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sellNotable cluster of 5

Yvonne Greenstreet sold $4.0M of ALNY

Chief Executive Officer at ALNYLAM PHARMACEUTICALS, INC.. 8,924 shares at an average of $452.05, traded Oct 2, 2025, filed Oct 3, 2025.

Warning score
70
Value
$4.0M
8,924 shares
Holdings after
65,409
-12% from before
From 52-week low
+106%
low $224.32, close $460.99
From 52-week high
-4%
high $482.13, as of Oct 2, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $4.0M at market
    +25
  • Share of holdings sold
    Sold 12% of holdings
    +5
  • Cluster
    5 insiders selling within 14 days
    +15

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ALNYOct 9, 2026 · close 232.68
Since filing Oct 3, 2025: -49.0%SPY +17.6% · excess -66.6%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001735276-25-000116, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Oct 1, 2025AGrant or award
Common Stock
+3,860$0.00$060,081Oct 3, 2025
Oct 1, 2025AGrant or award
Common Stock
+14,252$0.00$074,333Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-350$446.53$156k73,983Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-171$447.92$77k73,812Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-548$448.77$246k73,264Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-758$449.79$341k72,506Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-1,642$450.81$740k70,864Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-1,010$451.86$456k69,854Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-2,029$452.69$919k67,825Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-999$453.77$453k66,826Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-741$454.84$337k66,085Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-221$455.82$101k65,864Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-446$457.43$204k65,418Oct 3, 2025
Oct 2, 2025SOpen-market sale
Common Stock
-9$457.64$4,11965,409Oct 3, 2025

Related signals

Other insiders at ALNYLAM PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
36Weak
ALNYsell
ALNYLAM PHARMACEUTICALS, INC.
Bryan Supran
EVP, CLO and Secretary
$399k
1,758 shares
-12%
25Weak
ALNYsell10b5-1
ALNYLAM PHARMACEUTICALS, INC.
David E I Pyott
director
$1.1M
3,830 shares
-71%
30Weak
ALNYsell10b5-1
ALNYLAM PHARMACEUTICALS, INC.
Melissa McLaughlin
Chief Human Resources Officer
$1.3M
3,910 shares
-29%
26Weak
ALNYsell 510b5-1
ALNYLAM PHARMACEUTICALS, INC.
Kevin Joseph Fitzgerald
CSO & EVP, Head of Research
$418k
1,291 shares
-6%
51Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Tolga Tanguler
EVP, Chief Commercial Officer
$746k
2,309 shares
-6%
59Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Jeffrey V. Poulton
EVP, Chief Financial Officer
$797k
2,468 shares
-4%
64Notable
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Yvonne Greenstreet
Chief Executive Officer
$948k
2,933 shares
-3%
40Moderate
ALNYsell 510b5-1
ALNYLAM PHARMACEUTICALS, INC.
Pushkal Garg
EVP Chief R&D
$1.5M
4,713 shares
-20%
65Notable
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Yvonne Greenstreet
Chief Executive Officer
$2.2M
6,799 shares
-6%
48Moderate
ALNYsell 5
ALNYLAM PHARMACEUTICALS, INC.
Tolga Tanguler
EVP, Chief Commercial Officer
$524k
1,598 shares
-4%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Yvonne Greenstreet sold $4.0M of ALNY | InsiderTell