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buyModerate cluster of 2

Maria-Luisa Maccecchini bought $200k of ANVS

President & CEO at Annovis Bio, Inc.. 97,561 shares at an average of $2.05, traded Oct 28, 2025, filed Nov 12, 2025.

Conviction score
48
Value
$200k
97,561 shares
Holdings after
1,212,020
+9% from before
From 52-week low
-
no price yet
From 52-week high
-
no price yet

Score components

  • Role
    CEO
    +25
  • Trade size
    $200k at market
    +12
  • Relative to holdings
    Holdings up 9%
    +3
  • Price context
    No price history yet
    0
  • Cluster
    2 insiders buying within 14 days
    +8
  • Repeat buying
    First buy in 90 days
    0
  • Track record
    Too few past buys to judge (0 with prices)
    0

What happened after comparable buys

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m +70.0%, 3m -2.5%, 6m -8.6%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ANVSOct 13, 2026 · close 1.06
Since filing Nov 12, 2025: -56.4%SPY +15.1% · excess -71.5%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001104659-25-109906, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Oct 28, 2025POpen-market purchase
Common Stock
+97,561$2.05$200k1,212,020Nov 12, 2025

Related signals

Other insiders at Annovis Bio, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
39Weak
ANVSbuy
Annovis Bio, Inc.
Michael B Hoffman
director
$143k
76,344 shares
+2%
54Moderate
ANVSbuy
Annovis Bio, Inc.
Michael B Hoffman
director
$1.5M
713,800 shares
+28%
32Weak
ANVSbuy
Annovis Bio, Inc.
Michael B Hoffman
director
$194k
45,000 shares
+2%
31Weak
ANVSbuy
Annovis Bio, Inc.
Michael B Hoffman
director
$160k
39,200 shares
+2%
31Weak
ANVSbuy
Annovis Bio, Inc.
Michael B Hoffman
director
$160k
39,200 shares
+2%
23Weak
ANVSbuy
Annovis Bio, Inc.
Michael B Hoffman
director
$70k
20,000 shares
+1%
20Weak
ANVSbuy
Annovis Bio, Inc.
Michael B Hoffman
director
$32k
15,000 shares
+1%
58Moderate
ANVSbuy 2
Annovis Bio, Inc.
Michael B Hoffman
director
$2.0M
975,610 shares
+66%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Maria-Luisa Maccecchini bought $200k of ANVS | InsiderTell