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sellModerate cluster of 210b5-1 plan

Herriot Tabuteau sold $5.4M of AXSM

Chief Executive Officer at Axsome Therapeutics, Inc.. 45,384 shares at an average of $119.38, traded Oct 6, 2025, filed Oct 8, 2025.

Warning score
43
Value
$5.4M
45,384 shares
Holdings after
7,229
-172% from before
From 52-week low
+50%
low $80.05, close $119.94
From 52-week high
-13%
high $137.75, as of Oct 6, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $5.4M at market
    +25
  • Share of holdings sold
    Sold 100% of holdings
    +20
  • Cluster
    2 insiders selling within 14 days
    +8
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

AXSMOct 9, 2026 · close 168.35
Since filing Oct 8, 2025: +41.8%SPY +16.9% · excess +24.9%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-234881, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Oct 6, 2025MOption exercise
Common Stock10b5-1
+19,220$8.02$154k26,449Oct 8, 2025
Oct 6, 2025SOpen-market sale
Common Stock10b5-1
-19,220$120.17$2.3M7,229Oct 8, 2025
Oct 7, 2025MOption exercise
Common Stock10b5-1
+13,390$8.02$107k20,619Oct 8, 2025
Oct 7, 2025SOpen-market sale
Common Stock10b5-1
-13,390$118.77$1.6M7,229Oct 8, 2025
Oct 8, 2025MOption exercise
Common Stock10b5-1
+12,774$8.02$102k20,003Oct 8, 2025
Oct 8, 2025SOpen-market sale
Common Stock10b5-1
-12,774$118.84$1.5M7,229Oct 8, 2025
Oct 6, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-19,220$0.00$0441,900Oct 8, 2025
Oct 7, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-13,390$0.00$0428,510Oct 8, 2025
Oct 8, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-12,774$0.00$0415,736Oct 8, 2025

Related signals

Other insiders at Axsome Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
30Weak
AXSMsell10b5-1
Axsome Therapeutics, Inc.
Mark L. Jacobson
Chief Operating Officer
$2.1M
10,000 shares
-100%
38Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Mark L. Jacobson
Chief Operating Officer
$5.7M
35,378 shares
-100%
38Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Mark Coleman
director
$4.0M
25,000 shares
-35%
50Moderate
AXSMsell 310b5-1
Axsome Therapeutics, Inc.
Herriot Tabuteau
Chief Executive Officer
$6.0M
32,410 shares
-82%
40Moderate
AXSMsell 310b5-1
Axsome Therapeutics, Inc.
Ari Maizel
Chief Commercial Officer
$1.4M
7,500 shares
-100%
32Weak
AXSMsell 310b5-1
Axsome Therapeutics, Inc.
Nick Pizzie
Chief Financial Officer
$2.3M
12,000 shares
-22%
43Moderate
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Herriot Tabuteau
Chief Executive Officer
$24M
139,414 shares
-162%
33Weak
AXSMsell 210b5-1
Axsome Therapeutics, Inc.
Mark E Saad
director
$6.2M
37,577 shares
-231%
35Weak
AXSMsell10b5-1
Axsome Therapeutics, Inc.
Herriot Tabuteau
Chief Executive Officer
$12M
79,973 shares
-142%
35Weak
AXSMsell10b5-1
Axsome Therapeutics, Inc.
Herriot Tabuteau
Chief Executive Officer
$22M
163,939 shares
-166%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Herriot Tabuteau sold $5.4M of AXSM | InsiderTell