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sellNotable cluster of 10

AmirAli Talasaz sold $11M of GH

Co-Chief Executive Officer at Guardant Health, Inc.. 100,000 shares at an average of $105.05, traded Dec 8, 2025, filed Dec 10, 2025.

Warning score
75
Value
$11M
100,000 shares
Holdings after
168,223
-46% from before
From 52-week low
+242%
low $30.44, close $104.17
From 52-week high
-6%
high $111.25, as of Dec 8, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $10.5M at market
    +25
  • Share of holdings sold
    Sold 46% of holdings
    +10
  • Cluster
    10 insiders selling within 14 days
    +15

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

GHOct 9, 2026 · close 167.47
Since filing Dec 10, 2025: +63.2%SPY +14.5% · excess +48.7%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001753159-25-000006, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 8, 2025JOther
Common Stockindirect: Shares held by Talasaz Investments, L.P.
-387,946$0.00$082,854Dec 10, 2025
Dec 8, 2025JOther
Common Stockindirect: Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018
+193,973$0.00$0218,223Dec 10, 2025
Dec 8, 2025JOther
Common Stockindirect: Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018
+193,973$0.00$0218,223Dec 10, 2025
Dec 8, 2025SOpen-market sale
Common Stockindirect: Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018
-15,000$104.21$1.6M203,223Dec 10, 2025
Dec 8, 2025SOpen-market sale
Common Stockindirect: Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018
-30,760$105.34$3.2M172,463Dec 10, 2025
Dec 8, 2025SOpen-market sale
Common Stockindirect: Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018
-4,240$106.00$449k168,223Dec 10, 2025
Dec 8, 2025SOpen-market sale
Common Stockindirect: Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018
-15,000$104.21$1.6M203,223Dec 10, 2025
Dec 8, 2025SOpen-market sale
Common Stockindirect: Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018
-30,760$105.34$3.2M172,463Dec 10, 2025
Dec 8, 2025SOpen-market sale
Common Stockindirect: Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018
-4,240$106.00$449k168,223Dec 10, 2025

Related signals

Other insiders at Guardant Health, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
41Moderate
GHsell 510b5-1
Guardant Health, Inc.
Alex M Azar II
director
$145k
826 shares
-50%
55Moderate
GHsell 5
Guardant Health, Inc.
Darya Chudova
Chief Technology Officer
$1.4M
7,738 shares
-10%
65Notable
GHsell 5
Guardant Health, Inc.
Steve E. Krognes
director
$1.2M
6,674 shares
-46%
0Weak
GHsell 510b5-1
Guardant Health, Inc.
Musa Tariq
director
$20k
116 shares
-1%
50Moderate
GHsell 5
Guardant Health, Inc.
Kumud Kalia
Chief Information Officer
$632k
4,000 shares
-9%
10Weak
GHsell 910b5-1
Guardant Health, Inc.
Musa Tariq
director
$12k
116 shares
-1%
59Moderate
GHsell 10
Guardant Health, Inc.
Darya Chudova
Chief Technology Officer
$567k
5,451 shares
-44%
65Notable
GHsell 10
Guardant Health, Inc.
Helmy Eltoukhy
Co-Chief Executive Officer
$9.4M
90,565 shares
-4%
75Notable
GHsell 10
Guardant Health, Inc.
Darya Chudova
Chief Technology Officer
$2.4M
22,935 shares
-106%
46Moderate
GHsell 10
Guardant Health, Inc.
Medina Manuel Hidalgo
director
$131k
1,250 shares
-61%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

AmirAli Talasaz sold $11M of GH | InsiderTell