Skip to content
sellWeak cluster of 510b5-1 plan

Nello Mainolfi sold $8.9M of KYMR

Chief Executive Officer at Kymera Therapeutics, Inc.. 100,000 shares at an average of $89.17, traded Dec 8, 2025, filed Dec 8, 2025.

Warning score
35
Value
$8.9M
100,000 shares
Holdings after
660,482
-13% from before
From 52-week low
+348%
low $21.05, close $94.30
From 52-week high
0%
high $94.30, as of Dec 8, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $8.9M at market
    +25
  • Share of holdings sold
    Sold 13% of holdings
    +5
  • Cluster
    5 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

KYMROct 9, 2026 · close 112.40
Since filing Dec 8, 2025: +19.2%SPY +15.1% · excess +4.1%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-311504, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 8, 2025MOption exercise
Common Stock10b5-1
+100,000$2.08$208k760,482Dec 8, 2025
Dec 8, 2025SOpen-market sale
Common Stock10b5-1
-100,000$89.17$8.9M660,482Dec 8, 2025
Dec 8, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-100,000$0.00$0305,559Dec 8, 2025

Related signals

Other insiders at Kymera Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
KYMRsell10b5-1
Kymera Therapeutics, Inc.
Nello Mainolfi
Chief Executive Officer
$3.4M
30,000 shares
-4%
41Moderate
KYMRsell
Kymera Therapeutics, Inc.
Brian Adams
Chief Legal Officer
$744k
6,371 shares
-11%
23Weak
KYMRsell 210b5-1
Kymera Therapeutics, Inc.
Nello Mainolfi
Chief Executive Officer
$2.3M
30,000 shares
-4%
40Moderate
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Pamela Esposito
director
$2.3M
27,563 shares
-100%
55Moderate
KYMRsell 5
Kymera Therapeutics, Inc.
Bruce Booth
director
$22M
236,588 shares
-6%
50Moderate
KYMRbuy
Kymera Therapeutics, Inc.
Baker Bros. Advisors LP
director, owner
$172M
2,005,813 shares
+376%
32Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Jeffrey W. Albers
director
$449k
5,000 shares
-100%
30Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Jared Gollob
Chief Medical Officer
$4.4M
49,307 shares
-31%
23Weak
KYMRsell 210b5-1
Kymera Therapeutics, Inc.
Nello Mainolfi
Chief Executive Officer
$1.8M
30,000 shares
-4%
30Weak
KYMRsell 310b5-1
Kymera Therapeutics, Inc.
Jared Gollob
Chief Medical Officer
$3.7M
59,576 shares
-35%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Nello Mainolfi sold $8.9M of KYMR | InsiderTell