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sellWeak cluster of 210b5-1 plan

Nello Mainolfi sold $2.3M of KYMR

Chief Executive Officer at Kymera Therapeutics, Inc.. 30,000 shares at an average of $78.06, traded Dec 31, 2025, filed Dec 31, 2025.

Warning score
23
Value
$2.3M
30,000 shares
Holdings after
663,077
-4% from before
From 52-week low
+270%
low $21.05, close $77.81
From 52-week high
-17%
high $94.30, as of Dec 31, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $2.3M at market
    +25
  • Share of holdings sold
    Sold 4.3% of holdings
    0
  • Cluster
    2 insiders selling within 14 days
    +8
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -6.6%, 3m +9.2%, 6m +46.8%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

KYMROct 12, 2026 · close 112.08
Since filing Dec 31, 2025: +44.0%SPY +15.0% · excess +29.0%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-338415, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 31, 2025MOption exercise
Common Stock10b5-1
+30,000$2.08$62k693,077Dec 31, 2025
Dec 31, 2025SOpen-market sale
Common Stock10b5-1
-23,986$77.95$1.9M669,091Dec 31, 2025
Dec 31, 2025SOpen-market sale
Common Stock10b5-1
-6,014$78.52$472k663,077Dec 31, 2025
Dec 31, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-30,000$0.00$0275,559Dec 31, 2025

Related signals

Other insiders at Kymera Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
KYMRsell10b5-1
Kymera Therapeutics, Inc.
Nello Mainolfi
Chief Executive Officer
$3.4M
30,000 shares
-4%
41Moderate
KYMRsell
Kymera Therapeutics, Inc.
Brian Adams
Chief Legal Officer
$744k
6,371 shares
-11%
30Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Nello Mainolfi
Chief Executive Officer
$6.0M
50,000 shares
-7%
26Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Noah Goodman
Chief Business Officer
$387k
3,389 shares
-7%
32Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Bruce N. Jacobs
Chief Financial Officer
$8.9M
77,109 shares
-24%
35Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Nello Mainolfi
Chief Executive Officer
$9.2M
80,000 shares
-11%
35Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Bruce Booth
director
$8.3M
76,650 shares
-3%
40Moderate
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Bruce Booth
director
$56M
513,245 shares
-18%
35Weak
KYMRsell 510b5-1
Kymera Therapeutics, Inc.
Bruce Booth
director
$3.4M
31,283 shares
-1%
75Notable
KYMRsell 5
Kymera Therapeutics, Inc.
Bvf Partners L P/il
director, other
$174M
1,630,658 shares
-58%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Nello Mainolfi sold $2.3M of KYMR | InsiderTell