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sellWeak cluster of 410b5-1 plan

Orbimed Advisors LLC sold $4.8M of SION

director at Sionna Therapeutics, Inc.. 108,073 shares at an average of $44.55, traded Nov 24, 2025, filed Nov 26, 2025.

Warning score
35
Value
$4.8M
108,073 shares
Holdings after
3,596,886
-3% from before
From 52-week low
+479%
low $7.66, close $44.38
From 52-week high
0%
high $44.38, as of Nov 24, 2025

Score components

  • Role
    Director
    +15
  • Trade size
    $4.8M at market
    +25
  • Share of holdings sold
    Sold 2.9% of holdings
    0
  • Cluster
    4 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

SIONOct 9, 2026 · close 4.90
Since filing Nov 26, 2025: -88.8%SPY +15.8% · excess -104.6%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000947871-25-001045, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Nov 24, 2025SOpen-market sale
Common Stockindirect: See footnotes10b5-1
-94,583$44.54$4.2M3,610,376Nov 26, 2025
Nov 25, 2025SOpen-market sale
Common Stockindirect: See footnotes10b5-1
-11,890$44.60$530k3,598,486Nov 26, 2025
Nov 26, 2025SOpen-market sale
Common Stockindirect: See footnotes10b5-1
-1,600$44.49$71k3,596,886Nov 26, 2025

Related signals

Other insiders at Sionna Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
50Moderate
SIONsell
Sionna Therapeutics, Inc.
Ra Capital Management, L.p.
director, owner
$22M
3,448,811 shares
-50%
15Weak
SIONsell10b5-1
Sionna Therapeutics, Inc.
Jennifer Fitzpatrick
Chief Legal Officer
$347k
10,250 shares
-100%
37Weak
SIONsell
Sionna Therapeutics, Inc.
Tpg Gp A, LLC
owner
$10M
250,000 shares
-4%
28Weak
SIONsell 210b5-1
Sionna Therapeutics, Inc.
Orbimed Advisors LLC
director
$1.5M
33,356 shares
-1%
28Weak
SIONsell 210b5-1
Sionna Therapeutics, Inc.
Peter A. Thompson
director
$1.5M
33,356 shares
-1%
19Weak
SIONsell 310b5-1
Sionna Therapeutics, Inc.
Orbimed Advisors LLC
director
$83k
1,875 shares
-0%
19Weak
SIONsell 310b5-1
Sionna Therapeutics, Inc.
Peter A. Thompson
director
$83k
1,875 shares
-0%
31Weak
SIONsell 310b5-1
Sionna Therapeutics, Inc.
Jennifer Fitzpatrick
Chief Legal Officer
$415k
10,250 shares
-100%
35Weak
SIONsell 410b5-1
Sionna Therapeutics, Inc.
Peter A. Thompson
director
$4.8M
108,073 shares
-3%
55Moderate
SIONsell 3
Sionna Therapeutics, Inc.
Ra Capital Management, L.p.
director, owner
$1.2M
30,316 shares
-0%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Orbimed Advisors LLC sold $4.8M of SION | InsiderTell