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sellModerate cluster of 410b5-1 plan

Charles F Wagner Jr sold $6.4M of VRTX

EVP, CO & FO at VERTEX PHARMACEUTICALS INC / MA. 14,000 shares at an average of $456.00, traded Dec 3, 2025, filed Dec 5, 2025.

Warning score
45
Value
$6.4M
14,000 shares
Holdings after
37,725
-27% from before
From 52-week low
+26%
low $366.54, close $463.13
From 52-week high
-10%
high $513.76, as of Dec 3, 2025

Score components

  • Role
    Officer
    +15
  • Trade size
    $6.4M at market
    +25
  • Share of holdings sold
    Sold 27% of holdings
    +10
  • Cluster
    4 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -0.7%, 3m +0.3%, 6m -1.9%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

VRTXOct 9, 2026 · close 510.08
Since filing Dec 5, 2025: +12.0%SPY +14.8% · excess -2.8%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000875320-25-000247, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 3, 2025SOpen-market sale
Common Stock10b5-1
-7,000$451.00$3.2M44,725Dec 5, 2025
Dec 3, 2025SOpen-market sale
Common Stock10b5-1
-7,000$461.00$3.2M37,725Dec 5, 2025

Related signals

Other insiders at VERTEX PHARMACEUTICALS INC / MA and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
37Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Duncan McKechnie
EVP, Chief Commercial Officer
$800k
1,541 shares
-12%
32Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Ourania Tatsis
EVP, Chief Reg. & Quality Off.
$787k
1,500 shares
-3%
26Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Joy Liu
EVP and Chief Legal Officer
$416k
828 shares
-4%
24Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$288k
596 shares
-4%
27Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$471k
1,020 shares
-6%
33Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.8M
4,062 shares
-19%
25Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$785k
1,745 shares
-8%
18Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Joy Liu
EVP and Chief Legal Officer
$364k
828 shares
-4%
33Weak
VRTXsell 310b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$888k
1,974 shares
-8%
30Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$614k
1,354 shares
-5%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.