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sellWeak cluster of 610b5-1 plan

Kristen Ambrose sold $634k of VRTX

SVP & Chief Accounting Officer at VERTEX PHARMACEUTICALS INC / MA. 1,376 shares at an average of $460.43, traded Feb 11, 2026, filed Feb 12, 2026.

Warning score
35
Value
$634k
1,376 shares
Holdings after
10,127
-12% from before
From 52-week low
+26%
low $366.54, close $461.24
From 52-week high
-10%
high $513.76, as of Feb 11, 2026

Score components

  • Role
    Officer
    +15
  • Trade size
    $634k at market
    +20
  • Share of holdings sold
    Sold 12% of holdings
    +5
  • Cluster
    6 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

VRTXOct 9, 2026 · close 510.08
Since filing Feb 12, 2026: +9.7%SPY +15.2% · excess -5.5%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000875320-26-000036, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Feb 10, 2026FTax withholding
Common Stock10b5-1
-592$468.41$277k11,503Feb 12, 2026
Feb 11, 2026SOpen-market sale
Common Stock10b5-1
-1,376$460.43$634k10,127Feb 12, 2026

Related signals

Other insiders at VERTEX PHARMACEUTICALS INC / MA and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
20Weak
VRTXsell10b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.1M
2,329 shares
-7%
35Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.1M
2,329 shares
-6%
40Moderate
VRTXsell 810b5-1
VERTEX PHARMACEUTICALS INC / MA
Duncan McKechnie
EVP, Chief Commercial Officer
$1.3M
2,633 shares
-17%
40Moderate
VRTXsell 810b5-1
VERTEX PHARMACEUTICALS INC / MA
Duncan McKechnie
EVP, Chief Commercial Officer
$1.2M
2,437 shares
-14%
27Weak
VRTXsell 810b5-1
VERTEX PHARMACEUTICALS INC / MA
Joy Liu
EVP and Chief Legal Officer
$442k
892 shares
-4%
35Weak
VRTXsell 910b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.1M
2,329 shares
-6%
55Moderate
VRTXsell 910b5-1
VERTEX PHARMACEUTICALS INC / MA
Reshma Kewalramani
CEO & President
$20M
40,000 shares
-29%
21Weak
VRTXsell 910b5-1
VERTEX PHARMACEUTICALS INC / MA
Kristen Ambrose
SVP & Chief Accounting Officer
$173k
357 shares
-5%
20Weak
VRTXsell 910b5-1
VERTEX PHARMACEUTICALS INC / MA
Kristen Ambrose
SVP & Chief Accounting Officer
$108k
223 shares
-3%
24Weak
VRTXsell 910b5-1
VERTEX PHARMACEUTICALS INC / MA
Edward Morrow Atkinson III
EVP, Chief Technical Ops. Off.
$325k
668 shares
-3%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Kristen Ambrose sold $634k of VRTX | InsiderTell