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sellWeak cluster of 610b5-1 plan

Kristen Ambrose sold $108k of VRTX

SVP & Chief Accounting Officer at VERTEX PHARMACEUTICALS INC / MA. 223 shares at an average of $486.35, traded Feb 25, 2026, filed Feb 26, 2026.

Warning score
20
Value
$108k
223 shares
Holdings after
6,981
-3% from before
From 52-week low
+32%
low $366.54, close $483.05
From 52-week high
-6%
high $513.76, as of Feb 25, 2026

Score components

  • Role
    Officer
    +15
  • Trade size
    $108k at market
    +10
  • Share of holdings sold
    Sold 3.1% of holdings
    0
  • Cluster
    6 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

VRTXOct 9, 2026 · close 510.08
Since filing Feb 26, 2026: +6.2%SPY +13.8% · excess -7.6%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000875320-26-000104, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Feb 24, 2026FTax withholding
Common Stock10b5-1
-546$485.11$265k7,204Feb 26, 2026
Feb 25, 2026SOpen-market sale
Common Stock10b5-1
-223$486.35$108k6,981Feb 26, 2026

Related signals

Other insiders at VERTEX PHARMACEUTICALS INC / MA and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
20Weak
VRTXsell10b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.1M
2,329 shares
-7%
20Weak
VRTXsell10b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.1M
2,329 shares
-6%
35Weak
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.1M
2,329 shares
-6%
21Weak
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Kristen Ambrose
SVP & Chief Accounting Officer
$173k
357 shares
-5%
24Weak
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Edward Morrow Atkinson III
EVP, Chief Technical Ops. Off.
$325k
668 shares
-3%
27Weak
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Jonathan Biller
EVP and Chief Legal Officer
$460k
945 shares
-6%
24Weak
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Mark E. Bunnage
EVP, Chief Scientific Officer
$302k
620 shares
-8%
40Moderate
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Kristen Ambrose
SVP & Chief Accounting Officer
$1.1M
2,195 shares
-22%
40Moderate
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Edward Morrow Atkinson III
EVP, Chief Technical Ops. Off.
$1.4M
2,848 shares
-12%
40Moderate
VRTXsell 610b5-1
VERTEX PHARMACEUTICALS INC / MA
Jonathan Biller
EVP and Chief Legal Officer
$1.8M
3,720 shares
-19%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Kristen Ambrose sold $108k of VRTX | InsiderTell