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sellModerate cluster of 2

Ryan J. Watts sold $581k of DNLI

President and CEO at Denali Therapeutics Inc.. 35,198 shares at an average of $16.50, traded Jan 6, 2026, filed Jan 8, 2026.

Warning score
57
Value
$581k
35,198 shares
Holdings after
296,833
-11% from before
From 52-week low
+50%
low $11.47, close $17.21
From 52-week high
-27%
high $23.59, as of Jan 6, 2026

Score components

  • Role
    CEO
    +25
  • Trade size
    $581k at market
    +19
  • Share of holdings sold
    Sold 11% of holdings
    +5
  • Cluster
    2 insiders selling within 14 days
    +8

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

DNLIOct 9, 2026 · close 19.45
Since filing Jan 8, 2026: +13.9%SPY +13.8% · excess +0.1%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001724310-26-000004, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Jan 6, 2026SOpen-market sale
Common Stock
-35,198$16.50$581k296,833Jan 8, 2026

Related signals

Other insiders at Denali Therapeutics Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
36Weak
DNLIsell 3
Denali Therapeutics Inc.
Peter Scott Chin
Chief Medical Officer
$37k
1,654 shares
-1%
33Weak
DNLIsell 310b5-1
Denali Therapeutics Inc.
Nancy Thornberry
director
$262k
11,439 shares
-37%
18Weak
DNLIsell 310b5-1
Denali Therapeutics Inc.
Alexander O. Schuth
COFO and Secretary
$65k
2,768 shares
-1%
37Weak
DNLIsell 2
Denali Therapeutics Inc.
Alexander O. Schuth
COFO and Secretary
$284k
17,218 shares
-6%
10Weak
DNLIsell 210b5-1
Denali Therapeutics Inc.
Carole Ho
Chief Medical Officer
$52k
3,743 shares
-2%
29Weak
DNLIsell 2
Denali Therapeutics Inc.
Alexander O. Schuth
COFO and Secretary
$40k
2,937 shares
-1%
35Weak
DNLIsell10b5-1
Denali Therapeutics Inc.
Ryan J. Watts
President and CEO
$7.4M
495,282 shares
-66%
43Moderate
DNLIsell 5
Denali Therapeutics Inc.
Steve E. Krognes
director
$69k
3,339 shares
-11%
67Notable
DNLIsell 5
Denali Therapeutics Inc.
Ryan J. Watts
President and CEO
$751k
36,916 shares
-13%
44Moderate
DNLIsell 5
Denali Therapeutics Inc.
Alexander O. Schuth
COFO and Secretary
$308k
15,162 shares
-6%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Ryan J. Watts sold $581k of DNLI | InsiderTell