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sellModerate cluster of 510b5-1 plan

Daniel Janney sold $16M of KRYS

director at Krystal Biotech, Inc.. 60,161 shares at an average of $268.44, traded Feb 24, 2026, filed Feb 26, 2026.

Warning score
40
Value
$16M
60,161 shares
Holdings after
85,096
-159% from before
From 52-week low
+116%
low $123.36, close $266.90
From 52-week high
-9%
high $291.93, as of Feb 24, 2026

Score components

  • Role
    Director
    +15
  • Trade size
    $16.1M at market
    +25
  • Share of holdings sold
    Sold 100% of holdings
    +20
  • Cluster
    5 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -11.2%, 3m +12.3%, 6m +29.3%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

KRYSOct 12, 2026 · close 332.07
Since filing Feb 26, 2026: +20.2%SPY +13.8% · excess +6.4%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001711279-26-000021, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Feb 24, 2026MOption exercise
Common Stock10b5-1
+37,895$2.46$93k37,895Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-569$262.91$150k37,326Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-1,733$264.12$458k35,593Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-3,557$265.08$943k32,036Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-8,986$266.18$2.4M23,050Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-11,673$266.97$3.1M11,377Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-6,671$268.04$1.8M4,706Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-3,963$268.97$1.1M743Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-370$269.83$100k373Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stock10b5-1
-373$271.09$101k0Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-62$263.05$16k107,300Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-900$264.60$238k106,400Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-1,604$265.54$426k104,796Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-4,339$266.62$1.2M100,457Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-1,891$267.37$506k98,566Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-1,674$268.67$450k96,892Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-930$269.50$251k95,962Feb 26, 2026
Feb 24, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-2,425$274.90$667k93,537Feb 26, 2026
Feb 25, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-700$275.00$193k92,837Feb 26, 2026
Feb 26, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-5,103$275.28$1.4M87,734Feb 26, 2026
Feb 26, 2026SOpen-market sale
Common Stockindirect: Directly beneficially owned by Alta Bioequities, L.P.10b5-1
-2,638$276.32$729k85,096Feb 26, 2026
Feb 24, 2026MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-37,895$0.00$00Feb 26, 2026

Related signals

Other insiders at Krystal Biotech, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
38Weak
KRYSsell 210b5-1
Krystal Biotech, Inc.
Krish S Krishnan
President and CEO
$9.0M
25,000 shares
-2%
33Weak
KRYSsell 210b5-1
Krystal Biotech, Inc.
Suma Krishnan
President, R&D
$9.0M
25,000 shares
-2%
50Moderate
KRYSsell
Krystal Biotech, Inc.
Dino A Rossi
director
$8.2M
25,000 shares
-33%
15Weak
KRYSsell10b5-1
Krystal Biotech, Inc.
John Charles Thomas
EVP, General Counsel
$347k
1,000 shares
-100%
45Moderate
KRYSsell 310b5-1
Krystal Biotech, Inc.
Krish S Krishnan
President and CEO
$7.7M
25,000 shares
-2%
40Moderate
KRYSsell 310b5-1
Krystal Biotech, Inc.
Suma Krishnan
President, R&D
$7.7M
25,000 shares
-2%
42Moderate
KRYSsell 310b5-1
Krystal Biotech, Inc.
John Charles Thomas
EVP, General Counsel
$194k
642 shares
-100%
45Moderate
KRYSsell 510b5-1
Krystal Biotech, Inc.
Krish S Krishnan
President and CEO
$6.6M
25,000 shares
-2%
40Moderate
KRYSsell 510b5-1
Krystal Biotech, Inc.
Suma Krishnan
President, R&D
$6.6M
25,000 shares
-2%
40Moderate
KRYSsell 510b5-1
Krystal Biotech, Inc.
Daniel Janney
director
$3.3M
11,803 shares
-14%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Daniel Janney sold $16M of KRYS | InsiderTell