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sellModerate cluster of 1110b5-1 plan

Reshma Kewalramani sold $20M of VRTX

CEO & President at VERTEX PHARMACEUTICALS INC / MA. 40,000 shares at an average of $493.47, traded Feb 27, 2026, filed Mar 3, 2026.

Warning score
55
Value
$20M
40,000 shares
Holdings after
98,278
-29% from before
From 52-week low
+36%
low $366.54, close $496.83
From 52-week high
-3%
high $513.76, as of Feb 27, 2026

Score components

  • Role
    CEO
    +25
  • Trade size
    $19.7M at market
    +25
  • Share of holdings sold
    Sold 29% of holdings
    +10
  • Cluster
    11 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -7.5%, 3m -10.4%, 6m +15.5%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

VRTXOct 9, 2026 · close 510.08
Since filing Mar 3, 2026: +7.6%SPY +15.3% · excess -7.7%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000875320-26-000129, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-400$479.75$192k137,878Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-120$481.50$58k137,758Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-240$482.84$116k137,518Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-2,510$487.13$1.2M135,008Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-3,278$488.27$1.6M131,730Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-460$489.32$225k131,270Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-2,725$490.54$1.3M128,545Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-949$491.30$466k127,596Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-2,520$493.29$1.2M125,076Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-3,498$494.33$1.7M121,578Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-15,580$495.38$7.7M105,998Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-5,995$496.16$3.0M100,003Mar 3, 2026
Feb 27, 2026SOpen-market sale
Common Stock10b5-1
-1,725$496.95$857k98,278Mar 3, 2026

Related signals

Other insiders at VERTEX PHARMACEUTICALS INC / MA and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
37Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Duncan McKechnie
EVP, Chief Commercial Officer
$800k
1,541 shares
-12%
32Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Ourania Tatsis
EVP, Chief Reg. & Quality Off.
$787k
1,500 shares
-3%
26Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Joy Liu
EVP and Chief Legal Officer
$416k
828 shares
-4%
24Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$288k
596 shares
-4%
27Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$471k
1,020 shares
-6%
33Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$1.8M
4,062 shares
-19%
25Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$785k
1,745 shares
-8%
18Weak
VRTXsell 210b5-1
VERTEX PHARMACEUTICALS INC / MA
Joy Liu
EVP and Chief Legal Officer
$364k
828 shares
-4%
33Weak
VRTXsell 310b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$888k
1,974 shares
-8%
30Weak
VRTXsell 410b5-1
VERTEX PHARMACEUTICALS INC / MA
Carmen Bozic
EVP and CMO
$614k
1,354 shares
-5%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Reshma Kewalramani sold $20M of VRTX | InsiderTell