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sellWeak cluster of 410b5-1 plan

Third Rock Ventures V, L.P. sold $7.4M of SEPN

owner at Septerna, Inc.. 147,200 shares at an average of $50.27, traded Aug 12, 2026, filed Aug 14, 2026.

Warning score
32
Value
$7.4M
147,200 shares
Holdings after
6,068,391
-2% from before
From 52-week low
+341%
low $10.93, close $48.19
From 52-week high
0%
high $48.19, as of Aug 12, 2026

Score components

  • Role
    10% owner
    +12
  • Trade size
    $7.4M at market
    +25
  • Share of holdings sold
    Sold 2.4% of holdings
    0
  • Cluster
    4 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

SEPNOct 12, 2026 · close 37.56
Since filing Aug 14, 2026: -15.6%SPY +0.5% · excess -16.1%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-26-352692, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Aug 12, 2026SOpen-market sale
Common Stock10b5-1
+147,059$50.27$7.4M6,068,532Aug 14, 2026
Aug 12, 2026SOpen-market sale
Common Stock10b5-1
+141$51.08$7,2026,068,391Aug 14, 2026

Related signals

Other insiders at Septerna, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
0Weak
SEPNsell10b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$126k
3,333 shares
-3%
65Notable
SEPNsell 4
Septerna, Inc.
Ra Capital Management, L.p.
director, owner
$63M
1,493,000 shares
-27%
30Weak
SEPNsell 410b5-1
Septerna, Inc.
Elizabeth Bhatt
President and COO
$1.1M
25,000 shares
-13%
5Weak
SEPNsell 410b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$115k
3,334 shares
-3%
4Weak
SEPNsell 210b5-1
Septerna, Inc.
Elizabeth Bhatt
President and COO
$136k
4,000 shares
-2%
5Weak
SEPNsell 310b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$115k
3,333 shares
-3%
16Weak
SEPNsell 210b5-1
Septerna, Inc.
Samira Shaikhly
Chief People Officer
$77k
2,178 shares
-73%
11Weak
SEPNsell 210b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$533k
15,000 shares
-13%
20Weak
SEPNsell 210b5-1
Septerna, Inc.
Samira Shaikhly
Chief People Officer
$219k
6,250 shares
-89%
11Weak
SEPNsell10b5-1
Septerna, Inc.
Samira Shaikhly
Chief People Officer
$172k
5,935 shares
-88%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Third Rock Ventures V, L.P. sold $7.4M of SEPN | InsiderTell