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Insider · CIK 0001747528

Steven George Hughes

officer

Files at RNA (Avidity Biosciences, Inc.), RNA (Atrium Therapeutics, Inc.). First filing Jan 23, 2025, latest Jan 23, 2026.

In brief

Steven George Hughes files SEC Form 4 as officer at RNA (Avidity Biosciences, Inc.), and also at RNA (Atrium Therapeutics, Inc.). Since Jan 23, 2025, Steven George Hughes has reported 0 open-market buys worth $0 and 10 open-market sells worth $4.9M, the latest filed on Jan 23, 2026.

A track record needs three past buys with six months of prices behind them; Steven George Hughes has 0, so none is measured yet.

The newest scored trade: sold $355k of RNA on Jan 21, 2026, filed Jan 23, 2026, scored 30 (weak), under a 10b5-1 plan. In the last 12 months: 0 buys worth $0 and 3 sells worth $631k.

Track record
Not enough history
Fewer than three past buys with six months of prices.
Median 6-month excess
-
after past buys, n = 0
Hit rate
-
past buys that beat the index over 6 months
Open-market trades
0 / 10
$0 bought, $4.9M sold

Where the trades landed

Last year at the company this insider has traded most, with each buy and sell on the bar it happened.

RNA: Avidity Biosciences, Inc.

RNAOct 9, 2026 · close 8.40

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

Signals

This insider’s open-market buys and sells, scored.

ScoreCompanyValueHoldingsPrice contextFiled
30Weak
RNAsell 810b5-1
Avidity Biosciences, Inc.
$355k
4,895 shares
-13%-
21Weak
RNAsell 810b5-1
Avidity Biosciences, Inc.
$171k
2,373 shares
-6%-
0Weak
RNAsell 210b5-1
Avidity Biosciences, Inc.
$105k
2,209 shares
-5%-
4Weak
RNAsell 410b5-1
Avidity Biosciences, Inc.
$90k
2,208 shares
-5%-
3Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
$70k
1,542 shares
-4%-
5Weak
RNAsell 610b5-1
Avidity Biosciences, Inc.
$102k
2,208 shares
-5%-
3Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
$72k
1,542 shares
-4%-
40Moderate
RNAsell 710b5-1
Avidity Biosciences, Inc.
$3.5M
81,434 shares
-97%-
29Weak
RNAsell 610b5-1
Avidity Biosciences, Inc.
$297k
9,578 shares
-12%-
20Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
$113k
3,947 shares
-5%-

Planned sales

Form 144 notices this insider filed before selling restricted or control stock, newest first.

FiledCompanySharesValueSale datePast 3 months
Aug 13, 2025 RNA
Avidity Biosciences, Inc.
9,709
0.01% of outstanding
$449kAug 13, 2025$3.5M
Aug 6, 2025 RNA
Avidity Biosciences, Inc.
81,434
0.07% of outstanding
$3.1MAug 6, 2025none

Transactions

Every row this insider has filed, 45 in all, newest first.

DateCompanyTransactionSharesPriceValueHoldings afterFiled
Sep 18, 2026RNA
Atrium Therapeutics, Inc.
FTax withholding
Common Stock
-21,459$8.95$192k51,63821 d ago
Apr 20, 2026RNA
Atrium Therapeutics, Inc.
AGrant or award
Common Stock
+30,000$0.00$073,097Apr 22, 2026
Apr 20, 2026RNA
Atrium Therapeutics, Inc.
AGrant or award
Stock Option (Right to Buy)derivative
+60,000$0.00$060,000Apr 22, 2026
Feb 27, 2026RNA
Avidity Biosciences, Inc.
DDisposition to issuer
Common Stock
-115,857--0Feb 27, 2026
Feb 27, 2026RNA
Avidity Biosciences, Inc.
DDisposition to issuer
Stock Option (Right to Buy)derivative
-73,342--0Feb 27, 2026
Feb 27, 2026RNA
Avidity Biosciences, Inc.
DDisposition to issuer
Stock Option (Right to Buy)derivative
-74,000--0Feb 27, 2026
Feb 27, 2026RNA
Avidity Biosciences, Inc.
DDisposition to issuer
Stock Option (Right to Buy)derivative
-49,333--0Feb 27, 2026
Feb 27, 2026RNA
Avidity Biosciences, Inc.
DDisposition to issuer
Stock Option (Right to Buy)derivative
-68,458--0Feb 27, 2026
Feb 27, 2026RNA
Avidity Biosciences, Inc.
DDisposition to issuer
Stock Option (Right to Buy)derivative
-50,000--0Feb 27, 2026
Jan 21, 2026RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-2,017$72.45$146k34,477Jan 23, 2026
Jan 21, 2026RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-2,878$72.45$209k31,599Jan 23, 2026
Jan 7, 2026RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-2,373$72.23$171k36,494Jan 9, 2026
Oct 22, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+2,209$10.16$22k41,076Oct 24, 2025
Oct 22, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-2,209$47.54$105k38,867Oct 24, 2025
Oct 22, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-2,209$0.00$068,458Oct 24, 2025
Sep 22, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+2,208$10.16$22k41,075Sep 23, 2025
Sep 22, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-2,208$40.58$90k38,867Sep 23, 2025
Sep 22, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-2,208$0.00$070,667Sep 23, 2025
Sep 15, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+1,542$6.57$10k40,409Sep 17, 2025
Sep 15, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-1,542$45.41$70k38,867Sep 17, 2025
Sep 15, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-1,542$0.00$049,333Sep 17, 2025
Aug 22, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+2,208$10.16$22k41,075Aug 22, 2025
Aug 22, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-2,208$46.40$102k38,867Aug 22, 2025
Aug 22, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-2,208$0.00$072,875Aug 22, 2025
Aug 13, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+1,542$6.57$10k40,409Aug 15, 2025
Aug 13, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-1,542$46.66$72k38,867Aug 15, 2025
Aug 13, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-1,542$0.00$050,875Aug 15, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+11,283$15.96$180k84,133Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-11,283$42.74$482k72,850Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+12,334$6.57$81k85,184Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-12,334$42.74$527k72,850Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+6,167$22.47$139k79,017Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-6,167$42.74$264k72,850Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Common Stock10b5-1
+17,667$10.16$179k90,517Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-17,667$42.74$755k72,850Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-33,983$42.74$1.5M38,867Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-11,283$0.00$073,342Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-12,334$0.00$052,417Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-6,167$0.00$074,000Aug 8, 2025
Aug 6, 2025RNA
Avidity Biosciences, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-17,667$0.00$075,083Aug 8, 2025
Mar 20, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-9,578$31.06$297k72,850Mar 21, 2025
Jan 21, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-1,915$28.60$55k84,460Jan 23, 2025
Jan 21, 2025RNA
Avidity Biosciences, Inc.
SOpen-market sale
Common Stock10b5-1
-2,032$28.59$58k82,428Jan 23, 2025
Jan 6, 2025RNA
Avidity Biosciences, Inc.
AGrant or award
Common Stock
+25,000$0.00$086,375Jan 8, 2025
Jan 6, 2025RNA
Avidity Biosciences, Inc.
AGrant or award
Stock Option (Right to Buy)derivative
+50,000$0.00$050,000Jan 8, 2025

Questions about Steven George Hughes

Answered from the filings on this page, as of the latest one.

Is Steven George Hughes buying or selling?

In the last 12 months Steven George Hughes reported 0 open-market buys worth $0 and 3 open-market sells worth $631k on SEC Form 4; the latest was sold $355k of RNA on Jan 21, 2026. Grants, option exercises and tax withholding are not counted.

How did Steven George Hughes's past buys perform?

Not measured yet. InsiderTell needs three past buys with six months of prices to publish a track record, and Steven George Hughes has 0.

Where does Steven George Hughes file Form 4?

Steven George Hughes has filed Form 4 at RNA (Avidity Biosciences, Inc.) as Chief Medical Officer; RNA (Atrium Therapeutics, Inc.) as Chief Medical Officer. A Form 4 is required of officers, directors and holders of more than 10% of a share class within two business days of a trade.

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Steven George Hughes: insider trades and track record | InsiderTell