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sellWeak cluster of 410b5-1 plan

Steven George Hughes sold $90k of RNA

Chief Medical Officer at Avidity Biosciences, Inc.. 2,208 shares at an average of $40.58, traded Sep 22, 2025, filed Sep 23, 2025.

Warning score
4
Value
$90k
2,208 shares
Holdings after
38,867
-5% from before
From 52-week low
-
no price yet
From 52-week high
-
no price yet

Score components

  • Role
    Officer
    +15
  • Trade size
    $90k at market
    +9
  • Share of holdings sold
    Sold 5.4% of holdings
    0
  • Cluster
    4 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

RNAOct 9, 2026 · close 8.40
Since filing Feb 27, 2026: -43.1%SPY +18.7% · excess -61.7%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001599901-25-000190, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 22, 2025MOption exercise
Common Stock10b5-1
+2,208$10.16$22k41,075Sep 23, 2025
Sep 22, 2025SOpen-market sale
Common Stock10b5-1
-2,208$40.58$90k38,867Sep 23, 2025
Sep 22, 2025MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-2,208$0.00$070,667Sep 23, 2025

Related signals

Other insiders at Avidity Biosciences, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
0Weak
RNAsell 210b5-1
Avidity Biosciences, Inc.
Steven George Hughes
Chief Medical Officer
$105k
2,209 shares
-5%
25Weak
RNAsell 310b5-1
Avidity Biosciences, Inc.
Teresa McCarthy
Chief Human Resources Officer
$1.0M
20,000 shares
-17%
14Weak
RNAsell 310b5-1
Avidity Biosciences, Inc.
Eric Mosbrooker
Chief Commercial Officer
$298k
6,562 shares
-11%
3Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
Steven George Hughes
Chief Medical Officer
$70k
1,542 shares
-4%
20Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
Teresa McCarthy
Chief Human Resources Officer
$621k
15,000 shares
-13%
22Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
W. Michael Flanagan
Chief Scientific Officer
$779k
20,000 shares
-20%
30Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
Troy Edward Wilson
director
$1.5M
29,500 shares
-35%
14Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
Eric Mosbrooker
Chief Commercial Officer
$309k
6,563 shares
-11%
35Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
Sarah Boyce
President and CEO
$2.5M
50,000 shares
-14%
10Weak
RNAsell 710b5-1
Avidity Biosciences, Inc.
Kathleen P. Gallagher
Chief Program Officer
$8,915
188 shares
-0%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Steven George Hughes sold $90k of RNA | InsiderTell