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Insider · CIK 0002038798

Sheldon Sloan

officer

Files at SYRE (Spyre Therapeutics, Inc.). First filing Apr 3, 2026, latest Jul 2, 2026.

In brief

Sheldon Sloan files SEC Form 4 as officer at SYRE (Spyre Therapeutics, Inc.). Since Apr 3, 2026, Sheldon Sloan has reported 0 open-market buys worth $0 and 4 open-market sells worth $7.4M, the latest filed on Jul 2, 2026.

A track record needs three past buys with six months of prices behind them; Sheldon Sloan has 0, so none is measured yet.

The newest scored trade: sold $731k of SYRE on Jul 1, 2026, filed Jul 2, 2026, scored 36 (weak), under a 10b5-1 plan. In the last 12 months: 0 buys worth $0 and 4 sells worth $7.4M.

Track record
Not enough history
Fewer than three past buys with six months of prices.
Median 6-month excess
-
after past buys, n = 0
Hit rate
-
past buys that beat the index over 6 months
Open-market trades
0 / 4
$0 bought, $7.4M sold

Where the trades landed

Last year at the company this insider has traded most, with each buy and sell on the bar it happened.

SYRE: Spyre Therapeutics, Inc.

SYREOct 9, 2026 · close 85.69

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

Signals

This insider’s open-market buys and sells, scored.

ScoreCompanyValueHoldingsPrice contextFiled
36Weak
SYREsell 510b5-1
Spyre Therapeutics, Inc.
$731k
8,334 shares
-100%+500% from low-11% from high
35Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
$625k
8,333 shares
-100%+401% from low-4% from high
40Moderate
SYREsell 410b5-1
Spyre Therapeutics, Inc.
$5.6M
78,333 shares
-100%+455% from low-7% from high
31Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
$398k
7,958 shares
-100%+314% from low-3% from high

Planned sales

Form 144 notices this insider filed before selling restricted or control stock, newest first.

FiledCompanySharesValueSale datePast 3 months
Jun 3, 2026 SYRE
SPYRE THERAPEUTICS INC
16,667
0.02% of outstanding
$1.2MJun 3, 2026$6.0M
May 1, 2026 SYRE
SPYRE THERAPEUTICS, INC.
78,333
0.10% of outstanding
$5.8MMay 1, 2026$398k
Apr 1, 2026 SYRE
SPYRE THERAPEUTICS INC
7,958
0.01% of outstanding
$401kApr 1, 2026none

Transactions

Every row this insider has filed, 20 in all, newest first.

DateCompanyTransactionSharesPriceValueHoldings afterFiled
Jul 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Common Stock10b5-1
+8,334$27.46$229k8,334Jul 2, 2026
Jul 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-6,500$87.52$569k1,834Jul 2, 2026
Jul 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-1,834$88.34$162k0Jul 2, 2026
Jul 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-8,334$0.00$0305,000Jul 2, 2026
Jun 3, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Common Stock10b5-1
+8,333$27.46$229k8,333Jun 3, 2026
Jun 3, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-8,333$75.00$625k0Jun 3, 2026
Jun 3, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-8,333$0.00$0313,334Jun 3, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Common Stock10b5-1
+78,333$27.46$2.2M78,333May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-21,306$69.53$1.5M57,027May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-19,656$70.61$1.4M37,371May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-8,777$71.56$628k28,594May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-12,777$72.94$932k15,817May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-10,358$73.74$764k5,459May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-5,059$74.60$377k400May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-400$75.37$30k0May 1, 2026
May 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-78,333$0.00$0321,667May 1, 2026
Apr 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Common Stock10b5-1
+7,958$21.66$172k7,958Apr 3, 2026
Apr 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-7,958$50.00$398k0Apr 3, 2026
Apr 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-7,958$0.00$087,542Apr 3, 2026
Jan 9, 2026SYRE
Spyre Therapeutics, Inc.
AGrant or award
Stock Option (Right to Buy)derivative
+140,000$0.00$0140,000Jan 13, 2026

Questions about Sheldon Sloan

Answered from the filings on this page, as of the latest one.

Is Sheldon Sloan buying or selling?

In the last 12 months Sheldon Sloan reported 0 open-market buys worth $0 and 4 open-market sells worth $7.4M on SEC Form 4; the latest was sold $731k of SYRE on Jul 1, 2026. Grants, option exercises and tax withholding are not counted.

How did Sheldon Sloan's past buys perform?

Not measured yet. InsiderTell needs three past buys with six months of prices to publish a track record, and Sheldon Sloan has 0.

Where does Sheldon Sloan file Form 4?

Sheldon Sloan has filed Form 4 at SYRE (Spyre Therapeutics, Inc.) as Chief Medical Officer. A Form 4 is required of officers, directors and holders of more than 10% of a share class within two business days of a trade.

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Sheldon Sloan: insider trades and track record | InsiderTell