Nasdaq · CIK 0001636282
SYRE Spyre Therapeutics, Inc.
Insider trading from SEC Form 4. Last filing 10 d ago. Close $85.69 on Oct 9, 2026, +353% from the 52-week low and -21% from the high.
Last 90 days
Net insider value
-$12M
more sold than bought
Buys
0
$0 by 0 insiders
Sells
6
$12M by 3 insiders
Insiders on file
9
with a Form 4 at this company
Price and insider trades, last year
SYREOct 9, 2026 · close 85.69
Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™
Signals
Open-market buys and sells at Spyre Therapeutics, Inc., scored.
| Score | Insider | Value | Holdings | Price context | Filed |
|---|---|---|---|---|---|
| 37Weak | Scott L Burrows Chief Financial Officer sell | $2.3M 25,000 shares | -26% | +460% from low-18% from high | |
| 40Moderate | Heidy King-Jones See Remarks sell | $2.6M 28,933 shares | -91% | +466% from low-17% from high | |
| 45Moderate | Cameron Turtle Chief Executive Officer sell | $1.4M 15,000 shares | -3% | +466% from low-17% from high | |
| 32Weak | Scott L Burrows Chief Financial Officer sell | $2.3M 25,732 shares | -24% | +497% from low-19% from high | |
| 40Moderate | Heidy King-Jones See Remarks sell | $2.5M 28,399 shares | -92% | +497% from low-19% from high | |
| 45Moderate | Cameron Turtle Chief Executive Officer sell | $1.3M 15,000 shares | -3% | +497% from low-19% from high | |
| 41Moderate | Scott L Burrows Chief Financial Officer sell | $300k 18,428 shares | -16% | +41% from low-58% from high | |
| 13Weak | Jeffrey W. Albers director sell | $246k 6,700 shares | -20% | - | |
| 0Weak | Jeffrey W. Albers director sell | $11k 300 shares | -1% | - |
Transactions
The last 56 rows filed, every code.
| Date | Insider | Transaction | Shares | Price | Value | Holdings after | Filed |
|---|---|---|---|---|---|---|---|
| Sep 30, 2026 | Scott L Burrows Chief Financial Officer | MOption exercise Common Stock10b5-1 | +17,500 | $14.50 | $254k | 97,262 | 10 d ago |
| Oct 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -600 | $89.14 | $53k | 551,940 | 10 d ago |
| Oct 1, 2026 | Heidy King-Jones See Remarks | MOption exercise Common Stock10b5-1 | +28,933 | $14.50 | $420k | 31,778 | 10 d ago |
| Sep 30, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -17,500 | $89.89 | $1.6M | 79,762 | 10 d ago |
| Oct 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -2,683 | $90.10 | $242k | 549,257 | 10 d ago |
| Oct 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -400 | $89.24 | $36k | 31,378 | 10 d ago |
| Oct 1, 2026 | Scott L Burrows Chief Financial Officer | MOption exercise Common Stock10b5-1 | +7,500 | $14.50 | $109k | 87,262 | 10 d ago |
| Oct 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -2,638 | $91.49 | $241k | 546,619 | 10 d ago |
| Oct 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -16,605 | $90.35 | $1.5M | 14,773 | 10 d ago |
| Oct 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -7,228 | $91.35 | $660k | 7,545 | 10 d ago |
| Oct 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -600 | $89.07 | $53k | 86,662 | 10 d ago |
| Oct 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -3,989 | $92.31 | $368k | 542,630 | 10 d ago |
| Oct 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -2,100 | $92.70 | $195k | 5,445 | 10 d ago |
| Oct 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -1,500 | $90.27 | $135k | 85,162 | 10 d ago |
| Oct 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -4,990 | $93.37 | $466k | 537,640 | 10 d ago |
| Oct 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -100 | $93.91 | $9,391 | 537,540 | 10 d ago |
| Oct 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -2,100 | $91.92 | $193k | 83,062 | 10 d ago |
| Oct 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -2,600 | $93.46 | $243k | 2,845 | 10 d ago |
| Oct 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -3,071 | $92.95 | $285k | 79,991 | 10 d ago |
| Oct 1, 2026 | Heidy King-Jones See Remarks | MOption exercise Stock Option (Right to Buy)derivative10b5-1 | -28,933 | $0.00 | $0 | 482,478 | 10 d ago |
| Oct 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -229 | $93.57 | $21k | 79,762 | 10 d ago |
| Sep 30, 2026 | Scott L Burrows Chief Financial Officer | MOption exercise Stock Option (Right to Buy)derivative10b5-1 | -17,500 | $0.00 | $0 | 319,857 | 10 d ago |
| Oct 1, 2026 | Scott L Burrows Chief Financial Officer | MOption exercise Stock Option (Right to Buy)derivative10b5-1 | -7,500 | $0.00 | $0 | 312,357 | 10 d ago |
| Sep 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -2,500 | $86.36 | $216k | 565,040 | 39 d ago |
| Sep 1, 2026 | Heidy King-Jones See Remarks | MOption exercise Common Stock10b5-1 | +27,999 | $14.50 | $406k | 30,844 | 39 d ago |
| Sep 1, 2026 | Scott L Burrows Chief Financial Officer | MOption exercise Common Stock10b5-1 | +7,500 | $14.50 | $109k | 105,494 | 39 d ago |
| Sep 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -8,400 | $87.15 | $732k | 556,640 | 39 d ago |
| Sep 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -4,845 | $86.40 | $419k | 25,999 | 39 d ago |
| Sep 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -900 | $86.25 | $78k | 104,594 | 39 d ago |
| Sep 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -4,384 | $87.11 | $382k | 100,210 | 39 d ago |
| Sep 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -3,700 | $88.06 | $326k | 552,940 | 39 d ago |
| Sep 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -16,548 | $87.20 | $1.4M | 9,451 | 39 d ago |
| Sep 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -2,016 | $88.03 | $177k | 98,194 | 39 d ago |
| Sep 1, 2026 | Cameron Turtle Chief Executive Officer | SOpen-market sale Common Stock10b5-1 | -400 | $89.07 | $36k | 552,540 | 39 d ago |
| Sep 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -6,206 | $88.17 | $547k | 3,245 | 39 d ago |
| Sep 1, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -400 | $89.38 | $36k | 2,845 | 39 d ago |
| Sep 1, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -200 | $89.04 | $18k | 97,994 | 39 d ago |
| Sep 2, 2026 | Heidy King-Jones See Remarks | MOption exercise Common Stock10b5-1 | +400 | $14.50 | $5,800 | 3,245 | 39 d ago |
| Sep 2, 2026 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock10b5-1 | -18,232 | $89.35 | $1.6M | 79,762 | 39 d ago |
| Sep 1, 2026 | Scott L Burrows Chief Financial Officer | MOption exercise Stock Option (Right to Buy)derivative10b5-1 | -7,500 | $0.00 | $0 | 337,357 | 39 d ago |
| Sep 2, 2026 | Heidy King-Jones See Remarks | SOpen-market sale Common Stock10b5-1 | -400 | $90.00 | $36k | 2,845 | 39 d ago |
| Sep 1, 2026 | Heidy King-Jones See Remarks | MOption exercise Stock Option (Right to Buy)derivative10b5-1 | -27,999 | $0.00 | $0 | 511,811 | 39 d ago |
| Sep 2, 2026 | Heidy King-Jones See Remarks | MOption exercise Stock Option (Right to Buy)derivative10b5-1 | -400 | $0.00 | $0 | 511,411 | 39 d ago |
| Sep 2, 2025 | Scott L Burrows Chief Financial Officer | SOpen-market sale Common Stock | -18,428 | $16.26 | $300k | 97,994 | Sep 3, 2025 |
| May 29, 2025 | Fairmount Funds Management LLC director | AGrant or award Stock Option (Right to Buy)derivativeindirect: By Peter Harwin | +25,000 | $0.00 | $0 | 25,000 | Jun 2, 2025 |
| May 29, 2025 | Laurie Stelzer director | AGrant or award Stock Option (Right to Buy)derivative | +25,000 | $0.00 | $0 | 25,000 | Jun 2, 2025 |
| May 29, 2025 | Sandra Milligan director | AGrant or award Stock Option (Right to Buy)derivative | +25,000 | $0.00 | $0 | 25,000 | Jun 2, 2025 |
| May 29, 2025 | Mark C. McKenna director | AGrant or award Stock Option (Right to Buy)derivative | +25,000 | $0.00 | $0 | 25,000 | Jun 2, 2025 |
| May 29, 2025 | Michael Thomas Henderson director | AGrant or award Stock Option (Right to Buy)derivative | +25,000 | $0.00 | $0 | 25,000 | Jun 2, 2025 |
| May 29, 2025 | Jeffrey W. Albers director | AGrant or award Stock Option (Right to Buy)derivative | +25,000 | $0.00 | $0 | 25,000 | Jun 2, 2025 |
| May 29, 2025 | Fairmount Funds Management LLC director | AGrant or award Stock Option (Right to Buy)derivativeindirect: By Tomas Kiselak | +25,000 | $0.00 | $0 | 25,000 | Jun 2, 2025 |
| Jan 15, 2025 | Scott L Burrows Chief Financial Officer | AGrant or award Stock Option (Right to Buy)derivative | +95,500 | $0.00 | $0 | 95,500 | Jan 17, 2025 |
| Jan 15, 2025 | Heidy King-Jones See Remarks | AGrant or award Stock Option (Right to Buy)derivative | +95,500 | $0.00 | $0 | 95,500 | Jan 17, 2025 |
| Jan 10, 2025 | Michael Thomas Henderson director | JOther Common Stock | +105,379 | $0.00 | $0 | 105,379 | Jan 14, 2025 |
| Nov 6, 2024 | Jeffrey W. Albers director | SOpen-market sale Common Stockindirect: By Sessions LLC10b5-1 | -6,700 | $36.76 | $246k | 27,360 | Nov 8, 2024 |
| Oct 25, 2024 | Jeffrey W. Albers director | SOpen-market sale Common Stockindirect: By Sessions LLC10b5-1 | -300 | $36.43 | $11k | 34,060 | Oct 28, 2024 |
Insiders
Everyone who has filed a Form 4 here.
- Jeffrey W. Albersdirector
- Scott L BurrowsChief Financial Officer
- Fairmount Funds Management LLCdirector, owner
- Michael Thomas Hendersonceo, officer, director
- Heidy King-JonesSee Remarks
- Mark C. McKennadirector, other
- Sandra Milliganpresident, officer, ceo, director
- Laurie Stelzerdirector
- Cameron TurtleChief Executive Officer
Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.