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sellModerate cluster of 310b5-1 plan

Cameron Turtle sold $1.4M of SYRE

Chief Executive Officer at Spyre Therapeutics, Inc.. 15,000 shares at an average of $95.51, traded Aug 3, 2026, filed Aug 5, 2026.

Warning score
45
Value
$1.4M
15,000 shares
Holdings after
567,540
-3% from before
From 52-week low
+541%
low $14.82, close $94.93
From 52-week high
-8%
high $102.70, as of Aug 3, 2026

Score components

  • Role
    CEO
    +25
  • Trade size
    $1.4M at market
    +25
  • Share of holdings sold
    Sold 2.6% of holdings
    0
  • Cluster
    3 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

SYREOct 13, 2026 · close 80.45
Since filing Aug 5, 2026: -22.9%SPY +1.3% · excess -24.2%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001636282-26-000099, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Aug 3, 2026SOpen-market sale
Common Stock10b5-1
-800$93.97$75k581,740Aug 5, 2026
Aug 3, 2026SOpen-market sale
Common Stock10b5-1
-7,157$95.10$681k574,583Aug 5, 2026
Aug 3, 2026SOpen-market sale
Common Stock10b5-1
-5,635$95.93$541k568,948Aug 5, 2026
Aug 3, 2026SOpen-market sale
Common Stock10b5-1
-1,392$96.82$135k567,556Aug 5, 2026
Aug 3, 2026SOpen-market sale
Common Stock10b5-1
-16$97.46$1,559567,540Aug 5, 2026

Related signals

Other insiders at Spyre Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
37Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$2.3M
25,000 shares
-26%
40Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Heidy King-Jones
See Remarks
$2.6M
28,933 shares
-91%
45Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Cameron Turtle
Chief Executive Officer
$1.4M
15,000 shares
-3%
32Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$2.3M
25,732 shares
-24%
40Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Heidy King-Jones
See Remarks
$2.5M
28,399 shares
-92%
45Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Cameron Turtle
Chief Executive Officer
$1.3M
15,000 shares
-3%
40Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Jeffrey W. Albers
director
$2.4M
23,000 shares
-460%
23Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$717k
7,500 shares
-7%
22Weak
SYREsell 510b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$658k
7,500 shares
-7%
36Weak
SYREsell 510b5-1
Spyre Therapeutics, Inc.
Sheldon Sloan
Chief Medical Officer
$731k
8,334 shares
-100%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Cameron Turtle sold $1.4M of SYRE | InsiderTell