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Insider · CIK 0001853327

Scott L Burrows

cfoofficer

Files at SYRE (Spyre Therapeutics, Inc.). First filing Sep 3, 2025, latest Oct 2, 2026.

Track record
Not enough history
Fewer than three past buys with six months of prices.
Median 6-month excess
-
after past buys, n = 0
Hit rate
-
past buys that beat the index over 6 months
Open-market trades
0 / 3
$0 bought, $4.8M sold

Where the trades landed

Last year at the company this insider has traded most, with each buy and sell on the bar it happened.

SYRE: Spyre Therapeutics, Inc.

SYREOct 9, 2026 · close 85.69

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value. Click a marked bar to open the signal.Charts by TradingView Lightweight Charts™

Signals

This insider’s open-market buys and sells, scored.

ScoreCompanyValueHoldingsPrice contextFiled
37Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
$2.3M
25,000 shares
-26%+460% from low-18% from high
32Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
$2.3M
25,732 shares
-24%+497% from low-19% from high
41Moderate
SYREsell
Spyre Therapeutics, Inc.
$300k
18,428 shares
-16%+41% from low-58% from high

Transactions

Every row this insider has filed, newest first.

DateCompanyTransactionSharesPriceValueHoldings afterFiled
Sep 30, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Common Stock10b5-1
+17,500$14.50$254k97,26210 d ago
Sep 30, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-17,500$89.89$1.6M79,76210 d ago
Oct 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Common Stock10b5-1
+7,500$14.50$109k87,26210 d ago
Oct 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-600$89.07$53k86,66210 d ago
Oct 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-1,500$90.27$135k85,16210 d ago
Oct 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-2,100$91.92$193k83,06210 d ago
Oct 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-3,071$92.95$285k79,99110 d ago
Oct 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-229$93.57$21k79,76210 d ago
Sep 30, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-17,500$0.00$0319,85710 d ago
Oct 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-7,500$0.00$0312,35710 d ago
Sep 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Common Stock10b5-1
+7,500$14.50$109k105,49439 d ago
Sep 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-900$86.25$78k104,59439 d ago
Sep 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-4,384$87.11$382k100,21039 d ago
Sep 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-2,016$88.03$177k98,19439 d ago
Sep 1, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-200$89.04$18k97,99439 d ago
Sep 2, 2026SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock10b5-1
-18,232$89.35$1.6M79,76239 d ago
Sep 1, 2026SYRE
Spyre Therapeutics, Inc.
MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-7,500$0.00$0337,35739 d ago
Sep 2, 2025SYRE
Spyre Therapeutics, Inc.
SOpen-market sale
Common Stock
-18,428$16.26$300k97,994Sep 3, 2025
Jan 15, 2025SYRE
Spyre Therapeutics, Inc.
AGrant or award
Stock Option (Right to Buy)derivative
+95,500$0.00$095,500Jan 17, 2025

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.