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sellWeak cluster of 310b5-1 plan

Scott L Burrows sold $2.3M of SYRE

Chief Financial Officer at Spyre Therapeutics, Inc.. 25,000 shares at an average of $90.47, traded Sep 30, 2026, filed Oct 2, 2026.

Warning score
37
Value
$2.3M
25,000 shares
Holdings after
79,762
-26% from before
From 52-week low
+460%
low $15.89, close $89.03
From 52-week high
-18%
high $108.92, as of Sep 30, 2026

Score components

  • Role
    CFO
    +22
  • Trade size
    $2.3M at market
    +25
  • Share of holdings sold
    Sold 26% of holdings
    +10
  • Cluster
    3 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

SYREOct 9, 2026 · close 85.69
Since filing Oct 2, 2026: -8.0%SPY +1.2% · excess -9.2%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001636282-26-000117, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 30, 2026MOption exercise
Common Stock10b5-1
+17,500$14.50$254k97,26210 d ago
Sep 30, 2026SOpen-market sale
Common Stock10b5-1
-17,500$89.89$1.6M79,76210 d ago
Oct 1, 2026MOption exercise
Common Stock10b5-1
+7,500$14.50$109k87,26210 d ago
Oct 1, 2026SOpen-market sale
Common Stock10b5-1
-600$89.07$53k86,66210 d ago
Oct 1, 2026SOpen-market sale
Common Stock10b5-1
-1,500$90.27$135k85,16210 d ago
Oct 1, 2026SOpen-market sale
Common Stock10b5-1
-2,100$91.92$193k83,06210 d ago
Oct 1, 2026SOpen-market sale
Common Stock10b5-1
-3,071$92.95$285k79,99110 d ago
Oct 1, 2026SOpen-market sale
Common Stock10b5-1
-229$93.57$21k79,76210 d ago
Sep 30, 2026MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-17,500$0.00$0319,85710 d ago
Oct 1, 2026MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-7,500$0.00$0312,35710 d ago

Related signals

Other insiders at Spyre Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
40Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Heidy King-Jones
See Remarks
$2.6M
28,933 shares
-91%
45Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Cameron Turtle
Chief Executive Officer
$1.4M
15,000 shares
-3%
32Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$2.3M
25,732 shares
-24%
40Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Heidy King-Jones
See Remarks
$2.5M
28,399 shares
-92%
45Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Cameron Turtle
Chief Executive Officer
$1.3M
15,000 shares
-3%
41Moderate
SYREsell
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$300k
18,428 shares
-16%
13Weak
SYREsell10b5-1
Spyre Therapeutics, Inc.
Jeffrey W. Albers
director
$246k
6,700 shares
-20%
0Weak
SYREsell10b5-1
Spyre Therapeutics, Inc.
Jeffrey W. Albers
director
$11k
300 shares
-1%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.