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sellWeak cluster of 310b5-1 plan

Scott L Burrows sold $2.3M of SYRE

Chief Financial Officer at Spyre Therapeutics, Inc.. 25,732 shares at an average of $88.75, traded Sep 1, 2026, filed Sep 3, 2026.

Warning score
32
Value
$2.3M
25,732 shares
Holdings after
79,762
-24% from before
From 52-week low
+497%
low $14.82, close $88.50
From 52-week high
-19%
high $108.92, as of Sep 1, 2026

Score components

  • Role
    CFO
    +22
  • Trade size
    $2.3M at market
    +25
  • Share of holdings sold
    Sold 24% of holdings
    +5
  • Cluster
    3 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

SYREOct 9, 2026 · close 85.69
Since filing Sep 3, 2026: -1.8%SPY +0.9% · excess -2.7%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001636282-26-000109, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 1, 2026MOption exercise
Common Stock10b5-1
+7,500$14.50$109k105,49440 d ago
Sep 1, 2026SOpen-market sale
Common Stock10b5-1
-900$86.25$78k104,59440 d ago
Sep 1, 2026SOpen-market sale
Common Stock10b5-1
-4,384$87.11$382k100,21040 d ago
Sep 1, 2026SOpen-market sale
Common Stock10b5-1
-2,016$88.03$177k98,19440 d ago
Sep 1, 2026SOpen-market sale
Common Stock10b5-1
-200$89.04$18k97,99440 d ago
Sep 2, 2026SOpen-market sale
Common Stock10b5-1
-18,232$89.35$1.6M79,76240 d ago
Sep 1, 2026MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-7,500$0.00$0337,35740 d ago

Related signals

Other insiders at Spyre Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
37Weak
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$2.3M
25,000 shares
-26%
40Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Heidy King-Jones
See Remarks
$2.6M
28,933 shares
-91%
45Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Cameron Turtle
Chief Executive Officer
$1.4M
15,000 shares
-3%
40Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Heidy King-Jones
See Remarks
$2.5M
28,399 shares
-92%
45Moderate
SYREsell 310b5-1
Spyre Therapeutics, Inc.
Cameron Turtle
Chief Executive Officer
$1.3M
15,000 shares
-3%
45Moderate
SYREsell 2
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$1.3M
15,000 shares
-13%
68Notable
SYREsell 2
Spyre Therapeutics, Inc.
Fairmount Funds Management LLC
director
$400M
4,684,781 shares
-100%
5Weak
SYREsell10b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$533k
7,500 shares
-7%
15Weak
SYREsell10b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$892k
12,500 shares
-11%
2Weak
SYREsell10b5-1
Spyre Therapeutics, Inc.
Scott L Burrows
Chief Financial Officer
$370k
7,500 shares
-7%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Scott L Burrows sold $2.3M of SYRE | InsiderTell