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buyModerate cluster of 2

Alan Ezekowitz bought $516k of SEPN

director at Septerna, Inc.. 86,681 shares at an average of $5.95, traded Mar 4, 2025, filed Mar 6, 2025.

Conviction score
51
Value
$516k
86,681 shares
Holdings after
104,101
+498% from before
From 52-week low
-
no price yet
From 52-week high
-
no price yet

Score components

  • Role
    Director
    +15
  • Trade size
    $516k at market
    +18
  • Relative to holdings
    Holdings up 498%
    +10
  • Price context
    No price history yet
    0
  • Cluster
    2 insiders buying within 14 days
    +8
  • Repeat buying
    First buy in 90 days
    0
  • Track record
    Too few past buys to judge (0 with prices)
    0

What happened after comparable buys

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -13.8%, 3m +65.4%, 6m +122.0%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

SEPNOct 12, 2026 · close 37.56
Since filing Mar 6, 2025: +490.6%SPY +38.5% · excess +452.0%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000950170-25-035064, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Mar 4, 2025POpen-market purchase
Common Stock
+7,491$6.35$48k24,911Mar 6, 2025
Mar 5, 2025POpen-market purchase
Common Stock
+37,835$5.82$220k62,746Mar 6, 2025
Mar 6, 2025POpen-market purchase
Common Stock
+41,355$6.00$248k104,101Mar 6, 2025

Related signals

Other insiders at Septerna, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
0Weak
SEPNsell10b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$126k
3,333 shares
-3%
65Notable
SEPNsell 4
Septerna, Inc.
Ra Capital Management, L.p.
director, owner
$63M
1,493,000 shares
-27%
32Weak
SEPNsell 410b5-1
Septerna, Inc.
Third Rock Ventures V, L.P.
owner
$7.4M
147,200 shares
-2%
30Weak
SEPNsell 410b5-1
Septerna, Inc.
Elizabeth Bhatt
President and COO
$1.1M
25,000 shares
-13%
5Weak
SEPNsell 410b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$115k
3,334 shares
-3%
4Weak
SEPNsell 210b5-1
Septerna, Inc.
Elizabeth Bhatt
President and COO
$136k
4,000 shares
-2%
5Weak
SEPNsell 310b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$115k
3,333 shares
-3%
16Weak
SEPNsell 210b5-1
Septerna, Inc.
Samira Shaikhly
Chief People Officer
$77k
2,178 shares
-73%
11Weak
SEPNsell 210b5-1
Septerna, Inc.
Daniel D. Long
SVP, Drug Discovery
$533k
15,000 shares
-13%
20Weak
SEPNsell 210b5-1
Septerna, Inc.
Samira Shaikhly
Chief People Officer
$219k
6,250 shares
-89%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Alan Ezekowitz bought $516k of SEPN | InsiderTell