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sellModerate cluster of 5

James M Frates sold $155k of AMLX

Chief Financial Officer at Amylyx Pharmaceuticals, Inc.. 10,558 shares at an average of $14.65, traded Sep 30, 2025, filed Oct 2, 2025.

Warning score
48
Value
$155k
10,558 shares
Holdings after
280,430
-4% from before
From 52-week low
+362%
low $2.94, close $13.59
From 52-week high
-9%
high $14.90, as of Sep 30, 2025

Score components

  • Role
    CFO
    +22
  • Trade size
    $155k at market
    +11
  • Share of holdings sold
    Sold 3.6% of holdings
    0
  • Cluster
    5 insiders selling within 14 days
    +15

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m +4.8%, 3m -9.1%, 6m +12.5%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

AMLXOct 13, 2026 · close 26.85
Since filing Oct 2, 2025: +102.0%SPY +17.5% · excess +84.5%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-228341, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Sep 30, 2025SOpen-market sale
Common Stock
-10,558$14.65$155k280,430Oct 2, 2025

Related signals

Other insiders at Amylyx Pharmaceuticals, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
18Weak
AMLXsell10b5-1
Amylyx Pharmaceuticals, Inc.
George M Milne Jr
director
$831k
30,000 shares
-4%
65Notable
AMLXsell 5
Amylyx Pharmaceuticals, Inc.
Justin B. Klee
Co-Chief Executive Officer
$980k
30,464 shares
-1%
65Notable
AMLXsell 5
Amylyx Pharmaceuticals, Inc.
Joshua B Cohen
Co-Chief Executive Officer
$981k
30,464 shares
-1%
44Moderate
AMLXsell 5
Amylyx Pharmaceuticals, Inc.
Gina Mazzariello
Chief Legal Officer
$310k
9,536 shares
-5%
52Moderate
AMLXsell 5
Amylyx Pharmaceuticals, Inc.
James M Frates
Chief Financial Officer
$350k
10,810 shares
-4%
44Moderate
AMLXsell 5
Amylyx Pharmaceuticals, Inc.
Camille L Bedrosian
Chief Medical Officer
$325k
10,028 shares
-3%
19Weak
AMLXsell10b5-1
Amylyx Pharmaceuticals, Inc.
Gina Mazzariello
Chief Legal Officer
$539k
30,000 shares
-14%
29Weak
AMLXbuy
Amylyx Pharmaceuticals, Inc.
Karen Firestone
director
$51k
3,800 shares
+6%
40Moderate
AMLXsell 5
Amylyx Pharmaceuticals, Inc.
Gina Mazzariello
Chief Legal Officer
$99k
6,844 shares
-5%
47Moderate
AMLXsell 5
Amylyx Pharmaceuticals, Inc.
James M Frates
Chief Financial Officer
$115k
7,909 shares
-5%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

James M Frates sold $155k of AMLX | InsiderTell