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sellWeak

Perceptive Advisors LLC sold $344k of LYRA

owner at Lyra Therapeutics, Inc.. 70,390 shares at an average of $4.89, traded Nov 6, 2025, filed Nov 10, 2025.

Warning score
37
Value
$344k
70,390 shares
Holdings after
18,659
-31% from before
From 52-week low
-
no price yet
From 52-week high
-
no price yet

Score components

  • Role
    10% owner
    +12
  • Trade size
    $344k at market
    +15
  • Share of holdings sold
    Sold 31% of holdings
    +10
  • Cluster
    No other insider selling within 14 days
    0

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -8.6%, 3m -65.5%, 6m -83.2%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

LYRAOct 12, 2026 · close 0.19
Since filing Nov 10, 2025: -95.7%SPY +15.4% · excess -111.1%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-274540, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Nov 6, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-28,902$5.18$150k200,480Nov 10, 2025
Nov 6, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-3,247$5.18$17k22,521Nov 10, 2025
Nov 7, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-17,746$4.75$84k182,734Nov 10, 2025
Nov 7, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-1,993$4.75$9,46020,528Nov 10, 2025
Nov 10, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-16,633$4.54$76k166,101Nov 10, 2025
Nov 10, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-1,869$4.54$8,48518,659Nov 10, 2025

Related signals

Other insiders at Lyra Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
10Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Jason Cavalier
Chief Financial Officer
$2,587
769 shares
-0%
13Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Maria Palasis
President & CEO
$5,726
1,702 shares
-0%
34Weak
LYRAsell
Lyra Therapeutics, Inc.
Perceptive Advisors LLC
owner
$183k
45,875 shares
-28%
10Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Jason Cavalier
Chief Financial Officer
$6,094
684 shares
-0%
13Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Maria Palasis
President & CEO
$14k
1,565 shares
-0%
39Weak
LYRAbuy
Lyra Therapeutics, Inc.
Harlan Waksal
Executive Chair
$74k
25,000 shares
+11%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Perceptive Advisors LLC sold $344k of LYRA | InsiderTell