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sellWeak

Perceptive Advisors LLC sold $183k of LYRA

owner at Lyra Therapeutics, Inc.. 45,875 shares at an average of $3.98, traded Nov 11, 2025, filed Nov 13, 2025.

Warning score
34
Value
$183k
45,875 shares
Holdings after
14,026
-28% from before
From 52-week low
-
no price yet
From 52-week high
-
no price yet

Score components

  • Role
    10% owner
    +12
  • Trade size
    $183k at market
    +12
  • Share of holdings sold
    Sold 28% of holdings
    +10
  • Cluster
    No other insider selling within 14 days
    0

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -4.8%, 3m -65.4%, 6m -80.4%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

LYRAOct 12, 2026 · close 0.19
Since filing Nov 13, 2025: -95.0%SPY +17.0% · excess -112.0%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001193125-25-280481, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Nov 11, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-4,783$4.31$21k161,318Nov 13, 2025
Nov 11, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-537$4.31$2,31718,122Nov 13, 2025
Nov 12, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-7,862$4.06$32k153,456Nov 13, 2025
Nov 12, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-883$4.06$3,58417,239Nov 13, 2025
Nov 13, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-28,597$3.90$112k124,859Nov 13, 2025
Nov 13, 2025SOpen-market sale
Common Stockindirect: See Footnotes
-3,213$3.90$13k14,026Nov 13, 2025

Related signals

Other insiders at Lyra Therapeutics, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
10Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Jason Cavalier
Chief Financial Officer
$2,587
769 shares
-0%
13Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Maria Palasis
President & CEO
$5,726
1,702 shares
-0%
37Weak
LYRAsell
Lyra Therapeutics, Inc.
Perceptive Advisors LLC
owner
$344k
70,390 shares
-31%
10Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Jason Cavalier
Chief Financial Officer
$6,094
684 shares
-0%
13Weak
LYRAsell 210b5-1
Lyra Therapeutics, Inc.
Maria Palasis
President & CEO
$14k
1,565 shares
-0%
39Weak
LYRAbuy
Lyra Therapeutics, Inc.
Harlan Waksal
Executive Chair
$74k
25,000 shares
+11%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Perceptive Advisors LLC sold $183k of LYRA | InsiderTell