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sellModerate cluster of 410b5-1 plan

Joseph H Wender sold $2.3M of IONS

director at IONIS PHARMACEUTICALS INC. 28,000 shares at an average of $80.82, traded Dec 1, 2025, filed Dec 3, 2025.

Warning score
45
Value
$2.3M
28,000 shares
Holdings after
36,035
-44% from before
From 52-week low
+221%
low $25.51, close $81.99
From 52-week high
-1%
high $82.73, as of Dec 1, 2025

Score components

  • Role
    Director
    +15
  • Trade size
    $2.3M at market
    +25
  • Share of holdings sold
    Sold 44% of holdings
    +10
  • Cluster
    4 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

IONSOct 9, 2026 · close 45.28
Since filing Dec 3, 2025: -44.7%SPY +15.1% · excess -59.7%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000874015-25-000288, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 1, 2025SOpen-market sale
Common Stockindirect: by Trust10b5-1
-20,571$80.67$1.7M43,464Dec 3, 2025
Dec 1, 2025SOpen-market sale
Common Stockindirect: by Trust10b5-1
-7,429$81.23$603k36,035Dec 3, 2025

Related signals

Other insiders at IONIS PHARMACEUTICALS INC and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
26Weak
IONSsell 510b5-1
IONIS PHARMACEUTICALS INC
Eugene Schneider
EVP, Chf Clinical Develop Ofcr
$412k
5,812 shares
-8%
47Moderate
IONSsell 1110b5-1
IONIS PHARMACEUTICALS INC
Elizabeth L Hougen
EVP, Finance & CFO
$16M
225,220 shares
-73%
40Moderate
IONSsell 1110b5-1
IONIS PHARMACEUTICALS INC
Kyle Jenne
EVP, Chf GL Pdt Str Ofcr
$2.8M
37,277 shares
-76%
40Moderate
IONSsell 1110b5-1
IONIS PHARMACEUTICALS INC
Brett P Monia
Chief Executive Officer
$12M
160,773 shares
-44%
37Weak
IONSsell 1110b5-1
IONIS PHARMACEUTICALS INC
Patrick R. O'Neil
EVP CLO & General Counsel
$764k
10,148 shares
-14%
40Moderate
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
C Frank Bennett
EVP, Chief Scientific Officer
$6.7M
85,089 shares
-51%
18Weak
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
Joseph Baroldi
EVP, Chief Business Officer
$531k
6,659 shares
-15%
30Weak
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
Shannon L. Devers
EVP, Chief Human Resources Ofc
$1.6M
20,106 shares
-47%
40Moderate
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
Allene M. Diaz
director
$4.4M
54,878 shares
-94%
40Moderate
IONSsell 1010b5-1
IONIS PHARMACEUTICALS INC
Joseph Klein III
director
$1.7M
21,332 shares
-66%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Joseph H Wender sold $2.3M of IONS | InsiderTell