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sellModerate cluster of 410b5-1 plan

Patrick O'Brien sold $3.1M of ARWR

COO at ARROWHEAD PHARMACEUTICALS, INC.. 49,493 shares at an average of $63.11, traded Jan 5, 2026, filed Jan 5, 2026.

Warning score
40
Value
$3.1M
49,493 shares
Holdings after
474,908
-9% from before
From 52-week low
+539%
low $9.99, close $63.88
From 52-week high
-10%
high $70.82, as of Jan 5, 2026

Score components

  • Role
    COO
    +20
  • Trade size
    $3.1M at market
    +25
  • Share of holdings sold
    Sold 9.4% of holdings
    0
  • Cluster
    4 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ARWROct 9, 2026 · close 62.75
Since filing Jan 5, 2026: -1.8%SPY +14.1% · excess -15.9%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001627183-26-000001, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 31, 2025GGift
Common Stock10b5-1
-560$0.00$0526,641Jan 5, 2026
Dec 31, 2025GGift
Common Stock10b5-1
-560$0.00$0526,081Jan 5, 2026
Dec 31, 2025GGift
Common Stock10b5-1
-560$0.00$0525,521Jan 5, 2026
Dec 31, 2025GGift
Common Stock10b5-1
-560$0.00$0524,961Jan 5, 2026
Dec 31, 2025GGift
Common Stock10b5-1
-560$0.00$0524,401Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-4,368$61.20$267k520,033Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-6,164$62.23$384k513,869Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-13,451$62.96$847k500,418Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-11,842$63.84$756k488,576Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-2,700$64.44$174k485,876Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-900$66.01$59k484,976Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-313$68.00$21k484,663Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-600$61.12$37k484,063Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-900$62.25$56k483,163Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-5,873$62.91$369k477,290Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-2,336$64.04$150k474,954Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-46$68.00$3,128474,908Jan 5, 2026

Related signals

Other insiders at ARROWHEAD PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
ARWRsell10b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$642k
10,000 shares
-4%
43Moderate
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$872k
13,187 shares
-0%
40Moderate
ARWRsell 410b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$2.5M
40,164 shares
-19%
30Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$3.6M
51,726 shares
-1%
28Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Mauro Ferrari
director
$527k
7,530 shares
-10%
35Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Adeoye Y Olukotun
director
$677k
10,000 shares
-23%
45Moderate
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$1.8M
26,031 shares
-1%
34Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
William D. Waddill
director
$566k
8,367 shares
-13%
36Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Victoria Vakiener
director
$679k
10,040 shares
-22%
65Notable
ARWRsell 6
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$5.4M
85,000 shares
-2%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.