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sellModerate cluster of 410b5-1 plan

James C Hamilton sold $2.5M of ARWR

Chief Medical Officer at ARROWHEAD PHARMACEUTICALS, INC.. 40,164 shares at an average of $63.11, traded Jan 5, 2026, filed Jan 5, 2026.

Warning score
40
Value
$2.5M
40,164 shares
Holdings after
171,958
-19% from before
From 52-week low
+539%
low $9.99, close $63.88
From 52-week high
-10%
high $70.82, as of Jan 5, 2026

Score components

  • Role
    Officer
    +15
  • Trade size
    $2.5M at market
    +25
  • Share of holdings sold
    Sold 19% of holdings
    +5
  • Cluster
    4 insiders selling within 14 days
    +15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ARWROct 9, 2026 · close 62.75
Since filing Jan 5, 2026: -1.8%SPY +14.1% · excess -15.9%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001830755-26-000002, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-4,625$61.24$283k207,497Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-6,090$62.28$379k201,407Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-14,792$63.01$932k186,615Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-12,711$63.95$813k173,904Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-1,200$64.49$77k172,704Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-437$65.97$29k172,267Jan 5, 2026
Jan 5, 2026SOpen-market sale
Common Stock10b5-1
-309$68.00$21k171,958Jan 5, 2026

Related signals

Other insiders at ARROWHEAD PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
8Weak
ARWRsell10b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Hongbo Lu
director
$228k
2,970 shares
-5%
34Weak
ARWRsell 210b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Daniel Joseph Apel
Chief Financial Officer
$934k
13,095 shares
-7%
25Weak
ARWRsell 210b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$750k
10,000 shares
-4%
15Weak
ARWRsell10b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$642k
10,000 shares
-4%
43Moderate
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$872k
13,187 shares
-0%
40Moderate
ARWRsell 410b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Patrick O'Brien
COO
$3.1M
49,493 shares
-9%
30Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$3.6M
51,726 shares
-1%
28Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Mauro Ferrari
director
$527k
7,530 shares
-10%
35Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Adeoye Y Olukotun
director
$677k
10,000 shares
-23%
45Moderate
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$1.8M
26,031 shares
-1%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

James C Hamilton sold $2.5M of ARWR | InsiderTell