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sellModerate cluster of 11

Brian Birchler sold $637k of IONS

EVP, Corp and Development Ops at IONIS PHARMACEUTICALS INC. 8,480 shares at an average of $75.11, traded Jan 16, 2026, filed Jan 20, 2026.

Warning score
40
Value
$637k
8,480 shares
Holdings after
60,435
-12% from before
From 52-week low
+199%
low $25.51, close $76.33
From 52-week high
-8%
high $83.17, as of Jan 16, 2026

Score components

  • Role
    Officer
    +15
  • Trade size
    $637k at market
    +20
  • Share of holdings sold
    Sold 12% of holdings
    +5
  • Cluster
    11 insiders selling within 14 days
    +15
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m +7.2%, 3m -3.5%, 6m -31.1%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

IONSOct 9, 2026 · close 45.28
Since filing Jan 20, 2026: -41.6%SPY +15.8% · excess -57.4%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0000874015-26-000063, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Jan 15, 2026MOption exercise
Common Stock
+20,089$0.00$068,915Jan 20, 2026
Jan 16, 2026SOpen-market sale
Common Stock
-8,480$75.11$637k60,435Jan 20, 2026
Jan 15, 2026AGrant or award
Performance Restricted Stock Unitsderivative
+25,800$0.00$079,138Jan 20, 2026
Jan 15, 2026MOption exercise
Restricted Stock Unitderivative
-20,089$0.00$041,126Jan 20, 2026
Jan 15, 2026AGrant or award
Restricted Stock Unitderivative
+9,675$0.00$050,801Jan 20, 2026

Related signals

Other insiders at IONIS PHARMACEUTICALS INC and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
45Moderate
IONSsell 610b5-1
IONIS PHARMACEUTICALS INC
C Frank Bennett
EVP, Chief Scientific Officer
$1.7M
20,536 shares
-25%
32Weak
IONSsell 810b5-1
IONIS PHARMACEUTICALS INC
Joseph Baroldi
EVP, Chief Business Officer
$452k
5,635 shares
-55%
30Weak
IONSsell 810b5-1
IONIS PHARMACEUTICALS INC
Eugene Schneider
EVP, Chf Clinical Develop Ofcr
$2.1M
26,000 shares
-25%
23Weak
IONSsell 810b5-1
IONIS PHARMACEUTICALS INC
Patrick R. O'Neil
EVP CLO & General Counsel
$246k
3,069 shares
-5%
43Moderate
IONSsell 810b5-1
IONIS PHARMACEUTICALS INC
Eric Swayze
EVP Research
$839k
10,602 shares
-33%
40Moderate
IONSsell 810b5-1
IONIS PHARMACEUTICALS INC
Brett P Monia
Chief Executive Officer
$6.8M
85,637 shares
-33%
14Weak
IONSsell 710b5-1
IONIS PHARMACEUTICALS INC
Spencer R Berthelsen
director
$588k
8,000 shares
-5%
40Moderate
IONSsell 710b5-1
IONIS PHARMACEUTICALS INC
Holly B. Kordasiewicz
EVP, Chief Development Officer
$4.5M
60,846 shares
-73%
7Weak
IONSsell 210b5-1
IONIS PHARMACEUTICALS INC
Spencer R Berthelsen
director
$605k
8,000 shares
-5%
20Weak
IONSsell 310b5-1
IONIS PHARMACEUTICALS INC
Brett P Monia
Chief Executive Officer
$356k
4,536 shares
-2%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Brian Birchler sold $637k of IONS | InsiderTell