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buyWeak

Opaleye Management Inc. bought $228k of CDXS

owner at CODEXIS, INC.. 85,000 shares at an average of $2.68, traded Jul 31, 2025, filed Aug 4, 2025.

Conviction score
38
Value
$228k
85,000 shares
Holdings after
12,545,000
+1% from before
From 52-week low
+36%
low $1.97, close $2.68
From 52-week high
-54%
high $5.81, as of Jul 31, 2025

Score components

  • Role
    10% owner
    +12
  • Trade size
    $228k at market
    +13
  • Relative to holdings
    Under 1% of holdings (0.7%)
    -5
  • Price context
    54% below the 52-week high
    +8
  • Cluster
    No other insider buying within 14 days
    0
  • Repeat buying
    6 buys in 90 days
    +5
  • Track record
    Median 6-month excess return +95% over 3 past buys
    +10
  • Outside holder
    A 10% owner who is not an officer or director
    -5

What happened after comparable buys

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -15.1%, 3m -20.4%, 6m -49.3%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

CDXSOct 9, 2026 · close 1.41
Since filing Aug 4, 2025: -50.4%SPY +25.0% · excess -75.3%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001641172-25-022060, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Jul 31, 2025POpen-market purchase
Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P.
+84,220$2.68$226k12,544,220Aug 4, 2025
Aug 4, 2025POpen-market purchase
Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P.
+780$2.84$2,21112,545,000Aug 4, 2025

Related signals

Other insiders at CODEXIS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
CDXSsell
CODEXIS, INC.
Raymond De Vre
director
$6,174
2,605 shares
-3%
15Weak
CDXSsell
CODEXIS, INC.
Stefan Lutz
Chief Scientific Officer
$6,641
5,862 shares
-4%
40Moderate
CDXSsell 3
CODEXIS, INC.
Alison Moore
President and CEO
$5,001
3,826 shares
-2%
30Weak
CDXSsell 3
CODEXIS, INC.
Georgia Erbez
See Remarks
$5,001
3,826 shares
-5%
30Weak
CDXSsell 3
CODEXIS, INC.
Stefan Lutz
Chief Scientific Officer
$3,257
2,492 shares
-2%
15Weak
CDXSsell
CODEXIS, INC.
Stefan Lutz
CSO
$7,950
4,685 shares
-3%
52Moderate
CDXSsell 3
CODEXIS, INC.
Opaleye Management Inc.
owner
$1.9M
1,063,211 shares
-8%
43Moderate
CDXSsell 2
CODEXIS, INC.
Opaleye Management Inc.
owner
$878k
514,341 shares
-5%
43Moderate
CDXSsell 2
CODEXIS, INC.
Opaleye Management Inc.
owner
$878k
514,341 shares
-5%
30Weak
CDXSsell 3
CODEXIS, INC.
Dennis P Wolf
director
$14k
8,952 shares
-6%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Opaleye Management Inc. bought $228k of CDXS | InsiderTell